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Background: Depression and anxiety symptoms are two common psychological disturbances in cervical cancer patients. We tested whether sense of coherence (SOC) mediates the association of perceived social support (PSS) with depression and anxiety symptoms among cervical cancer patients in China. Methods: We conducted a survey involving 294 cervical cancer patients aged ≥ 18 years from July to December 2020 at three hospitals in Liaoning Province, China; 269 patients completed the survey. We included a demographic questionnaire, the Multidimensional Scale of Perceived Social Support (MSPSS), Antonovsky's Sense of Coherence Scale, the Hamilton Depression Rating Scale, and the Zung Self-Rating Anxiety Scale (SAS) in this study. We used hierarchical regression analysis to examine the relationship among PSS, SOC, and symptoms of depression and anxiety. We used asymptotic and resampling strategies to explore the mediating effect of SOC. Results: PSS was negatively associated with depressive symptoms (r = − 0.439, P < 0.01) and anxiety symptoms (r = − 0.325, P < 0.01). SOC was negatively related to depressive symptoms (r = − 0.627, P < 0.01) and anxiety symptoms (r = − 0.411, P < 0.01). SOC partially mediated the association between PSS and depressive symptoms (a*b = − 0.23, BCa95% CI: [− 0.31, − 0.14]) and anxiety symptoms (a*b = − 0.15, BCa95% CI: [− 0.23, − 0.08]). The proportions of the mediating effect accounting for SOC were 49.78% and 41.73% for depressive symptoms and anxiety symptoms, respectively. Conclusion: The study showed that SOC could mediate the association between PSS and symptoms of depression and anxiety. This suggests that SOC might serve as a potential target for intervention in symptoms of depression and anxiety that accompany cervical cancer. [ABSTRACT FROM AUTHOR]

Background: Fatigue influences doctors' physical and mental health seriously, additionally, the topic has received wide attention recently. This study aimed to identify the association among resilience, perceived organizational support (POS) and fatigue, and to further explore whether POS could be a moderator in the association between resilience and fatigue in Chinese doctors.Methods: A cross-sectional study was conducted in Liaoning Province in China in 2018. Out of 1000 randomly selected doctors, 866 completed the Chalder Fatigue Scale, the Connor-Davidson Resilience Scale, Survey of Perceived Organizational Support, and the questions about demographic characteristics and job condition variables. The association among resilience, POS and resilience × POS interaction with physical and mental fatigue were examined by hierarchical multiple regression. Simple slope analysis was conducted to visualize the interaction.Results: The association between resilience and physical fatigue was gradually increased in the low (1 standard deviation [SD] below the mean, β = -0.127, P< 0.05), mean (β = -0.292, P < 0.05) and high (1 SD above the mean, β = -0.457, P < 0.05) groups of POS. Additionally, the association was also different in the low (1 SD below the mean, β = -0.240, P < 0.01), mean (β = -0.357, P < 0.01) and high (1 SD above the mean, β = -0.474, P < 0.01) groups of POS.Limitations: Due to the cross-sectional design, the study cannot draw any conclusion of causal relationships among study variables.Conclusions: POS could moderate the association among resilience, physical and mental fatigue. More interventions related to resilience and POS will be helpful to alleviate fatigue among Chinese doctors. [ABSTRACT FROM AUTHOR]