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This paper aims to examine the characteristics of steady burning of inclined polymethyl methacrylate (PMMA) slabs under different ambient pressures. A sequence of experiments concerning steady burning intensity and combustion efficiency of the sample were conducted under both normal pressure (Hefei: altitude 30 m, 100 kPa) and reduced pressure (Lhasa: altitude 3650 m, 64 kPa). An in situ calorimeter based on oxygen consumption method was employed to measure the heat release rate of materials. A semi-theoretical model based on convective heat feedback from the flame was proposed and fitted well with laminar-dominated flame over the inclined PMMA surface. The critical maximum side length of sample for laminar-dominated flame in Hefei is lower than Lhasa. The trend of combustion efficiency with increasing inclination angle shows a great difference under different pressure environments. [ABSTRACT FROM AUTHOR]