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The Municipal Museum of Zierikzee (The Netherlands) houses a loose-leafed herbarium containing 354 plant specimens, of which the provenance, age and maker were until recently unknown. By studying the plant specimens, paper, decorations and labels, an image was conveyed of an early 18th century herbarium that matched the description of a herbarium from the legacy of Jacob Ligtvoet (1684-1752), gardener in the Hortus botanicus of Leiden (The Netherlands) from 1703 till his death in 1752. This herbarium is one of the oldest garden herbaria of its kind and contains 306 unique species, of which 201 are currently native to the Netherlands. Exotic species come from the Mediterranean (81 spp.), South Africa (8), the Americas (10) and tropical Asia (7) and for the larger part from Europe and temperate Asia. Based on our comparison of names on the oldest labels, this collection of dried plants was probably started after publication of the first garden catalogue by the prefect of the Leiden hortus and professor of botany Herman Boerhaave (1710), but before the second edition in 1720. This historic herbarium reflects the state-of-the-art of botanical science and the international network of Dutch botanical gardens in the early 18th century. [ABSTRACT FROM AUTHOR]

Over the past 20 years, there has been a significant increase in publication in complex network analysis research, especially in community detection. Many methods were proposed to identify community structure. Each community identification algorithm has strengths and weaknesses due to the complexity of information. Among them, the optimisation methods are widely focused on. This paper focuses on an empirical study of two community detection algorithms based on agglomerative techniques using modularity metric: Louvain and Leiden. In this regard, the Louvain algorithm has been shown to produce a bad connection in the community and disconnected when executed iteratively. Therefore, the Leiden algorithm is designed to successively resolve the weaknesses. Performance comparisons between the two and their concept were summarised in detail, as well as the step-by-step learning process of the state-of-the-art algorithms. This study is important and beneficial to the future study of interdisciplinary data sciences of network analysis. First, it demonstrates that the Leiden method outperformed the Louvain algorithm in terms of modularity metric and running time. Second, the paper displays the use of these two algorithms on synthetic and real networks. The experiment was successful as it identified better performance, and future work is required to confirm and validate these findings. [ABSTRACT FROM AUTHOR]

University Libraries play a crucial role in moving towards Open Science, contributing to more transparent, reproducible and reusable research. The Center for Digital Scholarship (CDS) at Leiden University (LU) library is a scholarly lab that promotes open science literacy among Leiden's scholars by two complementary strategies: existing top-down structures are used to provide training and services, while bottom-up initiatives from the research community are actively supported by offering the CDS's expertise and facilities. An example of how bottom-up initiatives can blossom with the help of library structures such as the CDS is ReproHack. ReproHack -- a reproducibility hackathon -- is a grass-root initiative by young scholars with the goal of improving research reproducibility in three ways. First, hackathon attendees learn about reproducibility tools and challenges by reproducing published results and providing feedback to authors on their attempt. Second, authors can nominate their work and receive feedback on their reproducibility efforts. Third, the collaborative atmosphere helps building a community interested in making their own research reproducible. A first ReproHack in the Netherlands took place on November 30th, 2019, co-organised by the CDS at the LU Library with 44 participants from the fields of psychology, engineering, biomedicine, and computer science. For 19 papers, 24 feedback forms were returned and five papers were reported as successfully reproduced. Besides the researchers' learning experience, the event led to recommendations on how to enhance research reproducibility. The ReproHack format therefore provides an opportunity for libraries to improve scientific reproducibility through community engagement. [ABSTRACT FROM AUTHOR]

Simple Summary: A bibliometric analysis was carried out to know the evolution of research on genes associated with meat tenderness, of interest for the development of selection programs. Since 1993, studies have been limited to a few researchers in high-income countries due to the costs associated with the techniques. The main findings showed that the scientific production had a discontinuous growth because science experienced a significant change since approximately 2010. Marker-assisted selection was widely used, evaluating mainly CAPN (calpain) and CAST (calpastatin) genes for their contribution to meat tenderness, especially in cattle. However, the effects are small; therefore, genomic selection was implemented by genotyping thousands of single nucleotide polymorphisms (SNPs) for further explanation of genetic variation. The results shown are important for scholars to identify emerging methodologies and gaps in the literature and to know who the prolific authors and institutions in the field for possible collaborations, etc., are. Tenderness is one of the main characteristics of meat because it determines its price and acceptability. This is the first bibliometric study on the trend of research on the role of genes in meat tenderness. A total of 175 original and English-language articles published up to 2021 were retrieved from Scopus. The bibliometric analysis was carried out with VOSviewer (version 1.6.18, Eck and Waltman, Leiden, Netherlands) and complemented with the Analyze search results service from Scopus. Erroneous and duplicate data were eliminated, and incomplete information was added to standardize the results. Scientific production was evaluated by means of quantity, quality and structure indicators. As a first glance, 8.816% of authors have published more than 50% of papers mainly related to genes encoding the calpain (CAPN)-calpastatin (CAST) system and single nucleotide polymorphisms (SNPs). Among other findings, a strong link was found between the contribution of the main countries (led by the United States with) and their institutions (led by the USDA Agricultural Research Service with) to their gross domestic product. Most studies on the topic are published in the Journal of Animal Science, and other journals with high impact according to the number of citations and different metrics. Finally, when evaluating the most cited articles, the occurrence and association of the main keywords, it was confirmed that research is focused on the role of CAPN and CAST genes and of SNPs in beef tenderness. The change in science was emphasized; although marker-assisted selection is still used, genes have an infinitesimal effect on complex traits. Therefore, since about 2010, new research groups adopted genomic selection to evaluate dense panels of SNPs and better explain genetic variation in meat tenderness. [ABSTRACT FROM AUTHOR]

The sensitivity of focus to context has often been analyzed in terms of focus-based anaphoric relations between sentences and surrounding discourse. The literature, however, has also noted empirical difficulties for the anaphoric approach, and my goal in the present paper is to investigate what happens if we abandon the anaphoric view altogether. Instead of anaphoric felicity conditions, I propose that focus leads to infelicity only indirectly, when the semantic processes that it feeds—in particular, exhaustification and question formation—make an inappropriate contribution to discourse. I outline such an account, in line with Roberts (In Papers in semantics, Vol. 49 of Working papers in linguistics, 91–136, The Ohio State University, 1996) and incorporating recent insights from Büring (In Questions in discourse, Vol. 36 of Current research in the semantics/pragmatics interface, 6–44, Leiden: Brill, 2019) and Fox (In Proceedings of Sinn und Bedeutung 22, 403–434, 2019). This account, which I motivate on conceptual grounds, has no anaphoric conditions on focus placement and has only an economy condition as a potential felicity condition on focus. However, there are cases where the fine control offered by anaphoricity seems needed, either to block deaccenting that would be licensed by a question or to allow local deaccenting that is not warranted by a question. Such cases challenge non-anaphoric accounts such as the present one and appear to support recent anaphoric proposals such as Schwarzschild (In Making worlds accessible. Essays in honor of Angelika Kratzer, 167–192, 2020), Wagner (In The Wiley Blackwell companion to semantics, Oxford: Wiley-Blackwell, 2020), and Goodhue (Journal of Semantics 39: 117–158, 2022). I argue that this potential motivation for anaphoricity is only apparent and that to the extent that anaphoric conditions on focus from the literature are not inert, they are in fact harmful. [ABSTRACT FROM AUTHOR]

Mapping Travel: The Origins and Conventions of Western Journey Maps: By Jordana Dym. Journey maps are distinct from road maps, Dym argues, because they attend primarily to 'the personal and individual rather than the permanent and collective'. She highlights William Wey as a crucial figure here, not because he made maps - although he did annotate a map of Palestine with his list of places - but rather because he began to imagine the relationship between personal travel and the map. [Extracted from the article]

The article presents abstracts of papers presented at the 9th Annual Meeting of the Society for Cutaneous Ultrastructure Research, held at Leiden, the Netherlands, in April 1982. Fetal manifestation of bullous ichthyosiform erythroderma and prenatal diagnosis of the disease by means of electron microscopy of fetal skin biopsies was discussed. A female patient with a generalized congenital ichthyosis was presented. The clinical picture was characterized by a reticulate hyperkeratosis with a remarkable skin pattern. Immuno-electronmicroscopic study of Langerhans' cells was also presented.

Nowadays, the rapid growth of operational costs and human resource shortages increase the importance of the leakage reduction, and the pressure management. This paper presents an optimisation procedure placing pressure-reducing valves (PRVs) to minimise the water losses of real-life water distribution networks (WDNs). The number and placement of the valves are optimised from clustering perspective with the Leiden algorithm. The optimal settings of the valves are determined with a differential evolution algorithm, where a compound fitness function is applied. On the one hand, it minimises the leakages, on the other hand, evades the pressure-dependent consumer outages, i.e. it keeps the pressure above the desired. Seven real-life water distribution networks were analysed from the region of Western Hungary using the techniques. Moreover, three of them are analysed in details. The robustness of the achieved leakage reduction with the optimised PRV placement is analysed to the uncertainty of the leakage exponent. [ABSTRACT FROM AUTHOR]

Cardiovascular diseases, among which includes coronary artery disease, represent one of the most important causes of mortality and morbidity worldwide. Research aimed at determining the risk factors involved recognizes a group of "traditional" risk factors, but also more recent studies identified over 100 "novel" ones which may have a role in the disease. Among the latter is the thrombophilia profile of a patient, a pathology well-established for its involvement in venous thromboembolism, but with less studied implications in arterial thrombosis. This paper reviews the literature, explaining the pathophysiology of the thrombophilia causes associated most with coronary thrombosis events. Results of several studies on the subject, including a meta-analysis with over 60,000 subjects, determined the significant involvement of factor V Leiden, prothrombin G20210A mutation, plasminogen activator inhibitor–1 and antiphospholipid syndrome in the development of coronary artery disease. The mechanisms involved are currently at different stages of research, with some already established and used as therapeutic targets. [ABSTRACT FROM AUTHOR]

By 2030, the European Commission intends to halve chemical pesticide use and its consequent risks. Among pesticides, nematicides are chemical agents used to control parasitic roundworms in agriculture. In recent decades, researchers have been looking for more sustainable alternatives with the same effectiveness but a limited impact on the environment and ecosystems. Essential oils (EOs) are similar bioactive compounds and potential substitutes. Different studies on the use of EOs as nematicides are available in the Scopus database in the scientific literature. These works show a wider exploration of EO effects in vitro than in vivo on different nematode populations. Nevertheless, a review of which EOs have been used on different target nematodes, and how, is still not available. The aim of this paper is to explore the extent of EO testing on nematodes and which of them have nematicidal effects (e.g., mortality, effects on motility, inhibition of egg production). Particularly, the review aims to identify which EOs have been used the most, on which nematodes, and which formulations have been applied. This study provides an overview of the available reports and data to date, downloaded from Scopus, through (a) network maps created by VOSviewer software (version 1.6.8, Nees Jan van Eck and Ludo Waltman, Leiden, The Netherlands) and (b) a systematic analysis of all scientific papers. VOSviewer created maps with keywords derived from co-occurrence analysis to understand the main keywords used and the countries and journals which have published most on the topic, while the systematic analysis investigated all the documents downloaded. The main goal is to offer a comprehensive understanding of the potential use of EOs in agriculture as well as which directions future research should move toward. [ABSTRACT FROM AUTHOR]

In 1643, a manuscript was sent from Batavia to Amsterdam. It described in vivid detail a world virtually unknown to the West, that of South-Indian Hinduism, taken from the words of local Brahmins and drawn up by VOC minister Abraham Rogerius. It was not until 1651 that De Open-Deure tot het Verborgen Heydendom appeared from the presses of the Leiden printing house of François Hackius. By then, its author had died, and circumstances regarding the actual publication are shrouded in mystery. This is also true about the life of Abraham Rogerius and the identity of the Open-Deure's anonymous editor, A.W. JCtus. Traditionally associated with the Polish Socinian theologian Andreas Wissowatius, A.W's annotations added a wealth of scholarly detail to Rogerius plain narrative. In this paper, I greatly expand upon the existing biographies of Rogerius and draw lines between the various actors involved with the eventual publication of his writings. I provide a fresh insight into the editorial history and afterlife of the Open-Deure, showing that there are in fact two different editions that diverge at key points. Moreover, I demonstrate that the elusive A.W. JCtus is most certainly not Wissowatius, but instead the Leiden lawyer and politician Arnoldus Wittens. [ABSTRACT FROM AUTHOR]

One of the objects of the Municipal Museum Zierikzee (Province of Zealand, The Netherlands) is a historical herbarium referred to by the name the 'Zierikzee Herbarium'. The characteristics of the specimens in the Zierikzee Herbarium are so similar to those in a herbarium at Naturalis Biodiversity Center, Leiden (L), that both must originate from the same place and time. About the latter herbarium little is known, except that it was once owned by the army-surgeon Simon(e) d'Oignies (1740-1782). The Zierikzee Herbarium was recently described and analysed in detail by Offerhaus et al. (2021). It is hypothesised that the Zierikzee Herbarium is part of a herbarium made by Professor Martinus Wilhelmus Schwencke (1707-1785) and was used during his lectures for future pharmacists in his botanical garden in The Hague in the 1750s, and auctioned in Leiden in 1785. The presence in the Zierikzee Herbarium of a virtually complete set of medicinal plants mentioned in the 'Pharmacopoea Hagana' (Anonymous 1738) eventually led to the conclusion that these could not have been assembled before 1730. Based on the printed ornaments that are used to mount the plants in these, and the major Dutch herbaria of the 18th century, I argue that the plants in the Zierikzee Herbarium and the herbarium of D'Oignies were remounted at a later date. The hypothesis by Offerhaus et al. (2021: 12) that the Zierikzee Herbarium was started between 1710 and 1720 is rejected. Arguments are given why it is unlikely that the Zierikzee Herbarium, as is suggested by Offerhaus et al. (2021: 12), is the herbarium of the head gardener of the Leiden botanic garden, Jacob Ligtvoet (1684-1752) and was auctioned in 1752. [ABSTRACT FROM AUTHOR]

Background: Since the initial publication of clusterMaker, the need for tools to analyze large biological datasets has only increased. New datasets are significantly larger than a decade ago, and new experimental techniques such as single-cell transcriptomics continue to drive the need for clustering or classification techniques to focus on portions of datasets of interest. While many libraries and packages exist that implement various algorithms, there remains the need for clustering packages that are easy to use, integrated with visualization of the results, and integrated with other commonly used tools for biological data analysis. clusterMaker2 has added several new algorithms, including two entirely new categories of analyses: node ranking and dimensionality reduction. Furthermore, many of the new algorithms have been implemented using the Cytoscape jobs API, which provides a mechanism for executing remote jobs from within Cytoscape. Together, these advances facilitate meaningful analyses of modern biological datasets despite their ever-increasing size and complexity. Results: The use of clusterMaker2 is exemplified by reanalyzing the yeast heat shock expression experiment that was included in our original paper; however, here we explored this dataset in significantly more detail. Combining this dataset with the yeast protein–protein interaction network from STRING, we were able to perform a variety of analyses and visualizations from within clusterMaker2, including Leiden clustering to break the entire network into smaller clusters, hierarchical clustering to look at the overall expression dataset, dimensionality reduction using UMAP to find correlations between our hierarchical visualization and the UMAP plot, fuzzy clustering, and cluster ranking. Using these techniques, we were able to explore the highest-ranking cluster and determine that it represents a strong contender for proteins working together in response to heat shock. We found a series of clusters that, when re-explored as fuzzy clusters, provide a better presentation of mitochondrial processes. Conclusions: clusterMaker2 represents a significant advance over the previously published version, and most importantly, provides an easy-to-use tool to perform clustering and to visualize clusters within the Cytoscape network context. The new algorithms should be welcome to the large population of Cytoscape users, particularly the new dimensionality reduction and fuzzy clustering techniques. [ABSTRACT FROM AUTHOR]

"Cooking with Plants in Ancient Europe and Beyond: Interdisciplinary Approaches to the Archaeology of Plant Foods" is a compilation of 30 papers edited by Soultana Maria Valamoti, Anastasia Dimoula, and Maria Ntinou. The book explores the role of plants in the dietary habits of early humans and their contribution to human evolution. The authors examine various aspects of ancient plant food production in Europe and beyond, using a range of archaeological artifacts. The book highlights the cultural, social, and economic aspects of food preparation and consumption throughout history. It also discusses the use of interdisciplinary methods, such as laboratory research, ethnography, and experimental archaeology, to study culinary transformation. While the book primarily focuses on the Mediterranean region, it includes one article on the foodscape of the Indus Valley civilization. The book is a valuable resource for archaeology students, early career researchers, and specialists interested in the relationship between plants, food, and humanity. [Extracted from the article]

We propose a novel approach to retirement risk and its measurement. We define retirement risk as a shortfall of financial resources to meet the needs of a retiree's household, which is different from the inability to maintain a standard of living in retirement. Taking a subjective approach to risk, we operationalise it using the Leyden approach to estimate the minimum satisfactory income for a retiree household and compare it to the pension value. Using a logistic regression model, we estimate the effect of pension value and household and reference person characteristics. The retirement risk level strongly depends on the pension value, household composition, and the reference person's education attainment level, which also moderates the impact of the pension. This paper contributes to the literature by proposing a subjective retirement risk measurement method and offering a methodological tool that can be used with similar data from other countries. [ABSTRACT FROM AUTHOR]

Brain cell structure and function reflect neurodevelopment, plasticity, and aging; and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to noninvasively disentangle cellular structural features are needed and are a substantial focus of brain research. Diffusion‐weighted MRS (dMRS) gives access to diffusion properties of endogenous intracellular brain metabolites that are preferentially located inside specific brain cell populations. Despite its great potential, dMRS remains a challenging technique on all levels: from the data acquisition to the analysis, quantification, modeling, and interpretation of results. These challenges were the motivation behind the organization of the Lorentz Center workshop on "Best Practices & Tools for Diffusion MR Spectroscopy" held in Leiden, the Netherlands, in September 2021. During the workshop, the dMRS community established a set of recommendations to execute robust dMRS studies. This paper provides a description of the steps needed for acquiring, processing, fitting, and modeling dMRS data, and provides links to useful resources. [ABSTRACT FROM AUTHOR]

This paper presents a network science approach to investigate a health information dataset, the Sexual Acquisition and Transmission of HIV Cooperative Agreement Program (SATHCAP), to uncover hidden relationships that can be used to suggest targeted health interventions. From the data, four key target variables are chosen: HIV status, injecting drug use, homelessness, and insurance status. These target variables are converted to a graph format using four separate graph inference techniques: graphical lasso, Meinshausen Bühlmann (MB), k-Nearest Neighbors (kNN), and correlation thresholding (CT). The graphs are then clustered using four clustering methods: Louvain, Leiden, and NBR-Clust with VAT and integrity. Promising clusters are chosen using internal evaluation measures and are visualized and analyzed to identify marker attributes and key relationships. The kNN and CT inference methods are shown to give useful results when combined with NBR-Clust clustering. Examples of cluster analysis indicate that the methodology produces results that will be relevant to the public health community. [ABSTRACT FROM AUTHOR]

Numerous books and papers have been written about the life and work of the famous Leiden physician and botanist professor Herman Boerhaave (1668–1738). However, none of these publications mentions what has happened to his botanical collections. A set of loose herbarium sheets with labels written by Boerhaave is known to be present at Naturalis Biodiversity Center, Leiden. Furthermore, two bound herbaria attributed to Boerhaave are known to exist. The first, a four‐volume herbarium makes part of the Sloane Herbarium (Natural History Museum, London). The second is a voluminous one‐volume herbal at Copenhagen (Natural History Museum Denmark). Another single‐volume herbarium, traditionally referred to as the "Herbarium of Boerhaave", at Leiden (Naturalis) is discussed here as well. Are these true Boerhaave herbaria made by Boerhaave personally, or have these herbaria at least formed part of his private collection? Where could other herbaria of his be found, and what has happened to the herbaria that were auctioned together with his library after his death? These are the questions this paper will try to answer. [ABSTRACT FROM AUTHOR]

Performing network-based analysis on medical and biological data makes a wide variety of machine learning tools available. Clustering, which can be used for classification, presents opportunities for identifying hard-to-reach groups for the development of customized health interventions. Due to a desire to convert abundant DNA gene co-expression data into networks, many graph inference methods have been developed. Likewise there are many clustering and classification tools. This paper presents a comparison of techniques for graph inference and clustering, using different numbers of features, in order to select the best tuple of graph inference method, clustering method, and number of features according to a particular phenotype. An extensive machine learning based analysis of the REGARDS dataset is conducted, evaluating the CoNet and K-Nearest Neighbors (KNN) network inference methods, along with the Louvain, Leiden and NBR-Clust clustering techniques. Results from analysis involving five internal cluster evaluation indices show the traditional KNN inference method and NBR-Clust and Louvain clustering produce the most promising clusters with medical phenotype data. It is also shown that visualization can aid in interpreting the clusters, and that the clusters produced can identify meaningful groups indicating customized interventions. [ABSTRACT FROM AUTHOR]

The insight that optical vortex beams carry orbital angular momentum (OAM), which emerged in Leiden about 30 years ago, has since led to an ever expanding range of applications and follow-up studies. This paper starts with a short personal account of how these concepts arose. This is followed by a description of some recent ideas where the coupling of transverse orbital and spin angular momentum (SAM) in tightly focused laser beams produces interesting new effects. The deflection of a focused light beam by an atom in the focus is reminiscent of the Magnus effect known from aerodynamics. Momentum conservation dictates an accompanying light force on the atom, transverse to the optical axis. As a consequence, an atom held in an optical tweezer will be trapped at a small distance of up to λ/2π away from the optical axis, which depends on the spin state of the atom and the magnetic field direction. This opens up new avenues to control the state of motion of atoms in optical tweezers as well as potential applications in quantum gates and interferometry. [ABSTRACT FROM AUTHOR]

In 1643, a manuscript was sent from Batavia to Amsterdam. It described in vivid detail a world virtually unknown to the West, that of South-Indian Hinduism, taken from the words of local Brahmins and drawn up by VOC minister Abraham Rogerius. It was not until 1651 that De Open-Deure tot het Verborgen Heydendom appeared from the presses of the Leiden printing house of François Hackius. By then, its author had died, and circumstances regarding the actual publication are shrouded in mystery. This is also true about the life of Abraham Rogerius and the identity of the Open-Deure's anonymous editor, A.W. JCtus. Traditionally associated with the Polish Socinian theologian Andreas Wissowatius, A.W's annotations added a wealth of scholarly detail to Rogerius plain narrative. In this paper, I greatly expand upon the existing biographies of Rogerius and draw lines between the various actors involved with the eventual publication of his writings. I provide a fresh insight into the editorial history and afterlife of the Open-Deure, showing that there are in fact two different editions that diverge at key points. Moreover, I demonstrate that the elusive A.W. JCtus is most certainly not Wissowatius, but instead the Leiden lawyer and politician Arnoldus Wittens. [ABSTRACT FROM AUTHOR]

Objective: Altmetrics are claimed to measure the scientific, societal, educational, technological and economic impacts of science. They have some of these dimensions in common with university ranking and evaluating systems. Their results are, therefore, expected to be partially convergent with the systems'. Given the importance of the scientific and non-scientific impacts of science, this study investigated the correlations of universities' altmetrics with their total and dimensional scores in Nature Index, Leiden, Times Higher Education (THE) and Quacquarelli Symonds (QS). Methodology: Following a correlational design, it explored an available sample of the universities commonly ranked in the systems in 2017. The data were collected from online documents using checklists and analysed by the Spearman correlation. As Altmetric Attention Score (ASS) is efficient in that it integrates several indicators into a single one, it was used as the proxy of the universities' social performance. Findings: The universities showed significant positive correlations between their ASSs and their performance scores on the total and dimensional levels, except for industry income in THE, with an insignificant correlation, and proportion of collaborative publication less than 100 km. in Leiden, with an inverse correlation. The correlations ranged from weak to marginally strong. Conclusion: The positive relationships between the universities' performance and ASSs signified that there existed some similarities in what they measured. However, they were of weak-to-marginally strong powers, implying that the metrics differed in what they measured. The findings contribute to the existing knowledge by providing some evidence of convergence between university-level altmetrics and university performances in various dimensions. [ABSTRACT FROM AUTHOR]

Copyright of Journal of the Institute of Art History is the property of Radovi Instituta za Povijest Umjetnosti and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article presents information on a number of studies that are currently carried out at the Centre for Science and Technology Studies at the Leiden University, Leiden, the Netherlands. A first cluster of studies is related to ranking of world universities and a second to the effects of evaluation processes upon author publication practices and upon journal editorial practices. It is realised by publishers and policy makers that it is important to take into account the effects of evaluation processes, and particularly of the use of bibliometric indicators therein, upon author publication practices and upon journal editorial practices.

The article discusses the highlights of a conference titled "The World of Wang Shizhen: Cultural Politics and Political Culture in Sixteenth Century China" held in Leiden, the Netherlands, from June 13 to 14, 2003. Among the themes of the papers presented for discussion include political life, mysticism and culture, and aesthetic dimensions. An overview of the sessions held during the event is offered.

Drop out is a typical issue in longitudinal studies. When the missingness is non-ignorable, inference based on the observed data only may be biased. This paper is motivated by the Leiden 85+ study, a longitudinal study conducted to analyze the dynamics of cognitive functioning in the elderly. We account for dependence between longitudinal responses from the same subject using time-varying random effects associated with a heterogeneous hidden Markov chain. As several participants in the study drop out prematurely, we introduce a further random effect model to describe the missing data mechanism. The potential dependence between the random effects in the two equations (and, therefore, between the two processes) is introduced through a joint distribution specified via a latent structure approach. The application of the proposal to data from the Leiden 85+ study shows its effectiveness in modeling heterogeneous longitudinal patterns, possibly influenced by the missing data process. Results from a sensitivity analysis show the robustness of the estimates with respect to misspecification of the missing data mechanism. A simulation study provides evidence for the reliability of the inferential conclusions drawn from the analysis of the Leiden 85+ data. [ABSTRACT FROM AUTHOR]

Graph The following abstracts have been provided by the library of the African Studies Centre Leiden (ASCL), Leiden University, Leiden, The Netherlands. G.C. v.d. Bruinhorst I "A confirmation of what went before it": historicising the Shi i Swahili Qur an translation by Ali Jumaa Mayunga i In: Approaches to the Qur an in sub-Saharan Africa / edited by Zulfikar Hirji. ABSTRACT: In Ali Jumaa Mayunga's Qur an translation in Swahili, "Qur an inayobainisha" (The Qur an that Explains; 2003 and 2008) he treats not only purely ritual matters but puts even more emphasis on historical issues, often in the form of extensive annexes and inserted essays. Also the different interpretations of what happened after Muhammad's death and Shi i view on the created Qur an opposed to the Sunni interpretation of Qur an as eternal, are examples of the direct influence of early Islamic history on contemporary translation activities. [Extracted from the article]

Objective. The aim of the research is to point out the differences in the scientific discourse that prevail in the domains of information literacy and graduate employability. The previous research results of the two authors of this paper have shown a very weak overlap between the domains of information literacy and employability. In this research, through the analysis of the notions of skill and competence, the authors have tried to determine why these two very important notions from the context of employability do not contribute to the stronger connection between information literacy and the issue of youth employability. Methodology. The mapping and visualization of the domain of research was done by performing a bibliometric co-word analysis over the sets of documents extracted from the Scopus citation base. The analysis was carried out using the VOSviewer software developed at the Center for Science and Technology Studies in Leiden. Results. By constructing the model of the domains of information literacy and employability, the visual mapping of the key concepts has shown the differences that prevail in their discourse. The analysis was carried out through the concepts of skills and competences, which are characteristic terms related to graduate employability. From their position in the information literacy domain, it is evident that they are on the edge of the cluster of 'information literacy', in the environment and context of 'acquiring skills and competencies' that are very generally related to acquiring information literacy, regardless of work and/or employability. However, in the domain of employability, it is evident that they are at the center of the cluster of 'graduate employability', which embraces 'work and employability' on the one hand, and 'students and higher education' on the other hand. It is especially indicative that in the information literacy model constructed with minimal restrictions, there are no concepts related to work, employability or employment, which indicates that the entire discourse of the domain of information literacy is not oriented in that direction. Originality. So far, no comprehensive analysis of the employability domain and its discourse in the graduate employability segment has been carried out, especially from the information literacy point of view. This paper presents a specific aspect which suggests why the discourse of these two domains is different, although both terms of skills and competences are actively present. By using the methods and tools of visual mapping, the results are presented very intuitively, in a clear and easy manner. [ABSTRACT FROM AUTHOR]

Copyright of Dicenda: Cuadernos de Filologia Hispanica is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article presents the development in the field of psychology as of October 1990. From October 24-26, 1990 the Netherlands Institute of Mental Health will hold a conference in Leiden, Netherlands, to stimulate the international exchange of scientific knowledge, information, and experience and to give a new impetus to the pursuit of mental health as well as to present current research. The National Women's Studies Association awards several scholarships and fellowships to graduate students and other scholars.

2019 marks the 350th anniversary of the death of the famous seventeenth-century painter Rembrandt van Rijn. Rembrandt was born in 1606 in the city of Leiden, located in the Netherlands. Here he grew up, was educated and set up his early practice before moving to Amsterdam at age 31. He is the son of a miller's family, which lived and worked in the city at the dawn of the Dutch Golden Age – a period in which Leiden transformed from a medieval city to an early modern metropolis. Although the historical city fabric of Leiden is well preserved, the birthplace of the famous painter, unfortunately, has been demolished. Also, the surroundings are unrecognizable today. For this reason, the tourism and marketing department of the city asked Erfgoed Leiden, the regional heritage department, to make a 3D virtual reconstruction of Rembrandt's birthplace and its surrounding. It resulted in a multi-disciplinary collaboration between archivists, building archaeologist, and a 3D artist. This paper reflects this cooperation from historical research over aspects of the 3D modeling pipeline to the final products of the reconstruction. Following a reliability matrix, the data were categorized for their reliability after careful evaluation of their accuracy depending on the source. [ABSTRACT FROM AUTHOR]

The following abstracts have been provided by the African Studies Centre Leiden (ASCL) in Leiden, The Netherlands, and are taken from the ASCL library's online catalogue. On the library page http://www.ascleiden.nl/library/ you will also find the abstracts journal "African Studies Abstracts Online", which offers a quarterly overview of journal articles and edited works on Africa in the field of the social sciences and the humanities that are available in the ASCL library. ABSTRACT: Although scholarly research on African Pentecostalism's appropriation of the media is expanding, little has been done to analyse the faith's exuberant media self-branding by English-speaking West African Pentecostal actors in Catholic Flanders. [Extracted from the article]

However, just as Danto pointed out in connection to the appreciation of artworks, Morgan emphasises that "there is more to sport than meets the eye" (73): the intrinsic properties making up the formal structure of a particular sport determine what properties will be relevant in aesthetically engaging a sporting body. Somaesthetics and Sport: edited by Andrew Edgar, Leiden/Boston, Brill, 2022, x+260 pp., €124.02 (hardback), ISBN 978-90-04-51064-7; €148.59 (Ebook), ISBN 978-90-04-51065-4 The aesthetic force of sport - residing, for instance, in the graceful and purposeful movement of skilful bodies, the intensely absorbing drama of a sporting competition, or the immersion into the autotelic, embodied activity of overcoming obstacles set by the rules - has been fascinating the philosophy of sport since its inception in the 70s. [Extracted from the article]

Deficiency of protein C (PC), protein S (PS), antithrombin III (AT III), and homozygosity or combined heterozygosity for Factor V Leiden (FVL) and Factor II (FII) 20210A mutation represent severe hereditary thrombophilia (SHT) and are associated with a higher risk of early-onset venous thromboembolism (VTE). In literature, few papers have described the efficacy and safety of therapy with direct oral anticoagulants (DOACs) in VTE occurring in patients with SHT. In our setting, we identified 8 patients who have suffered from early-onset VTE and underwent therapy with DOACs (6 rivaroxaban, 2 apixaban). Among them, 2 AT III deficiency, 2 PC deficiency, 3 PS deficiency, 1 combined heterozygosity for FVL, and FII 20210A were detected. During the follow-up, neither recurrences of VTE nor hemorrhagic episodes were observed. This report describes the efficacy and safety of therapy with anti-Xa in the treatment and secondary prophylaxis of VTE in patients with SHT. [ABSTRACT FROM AUTHOR]

The subject of this paper is the study of the pre-Linnaean herbarium of Paolo Boccone (1633-1704) which is kept in Leiden (the Netherlands) and its connections with two works of the same author: the imprinted herbarium kept in Paris in the Bibliothèques Interuniversitaires de Médecine and the printed volume “Icones et Descriptiones” of 1674. By means of the comparative analysis of the three works we have verified the existence of numerous similarities (even a complete overlap) between the samples of the Leiden herbarium (some with visible traces of ink), the imprints of the Paris herbarium and the figures of “Icones et Descriptiones”. The drawings to be found in this work, thanks to the realistic fidelity that distinguishes them, have been used by various authors until quite recent times for the description of new taxa. This shows the importance and the usefulness of the herbarium in question for the processes of typification. The taxonomic identification of the specimens (121 angiosperms and 1 alga) allowed us to designate the lectotype and the epitype of Daucus gingidium subsp. polygamus (Gouan) Onno and of Daucus carota subsp. commutatus (Paol.) Thell. [ABSTRACT FROM AUTHOR]

Germinating seedlings emit light in the visible range spontaneously, and these emissions are related to metabolism and reactive-oxygen species (ROS) processes. Several series of germination tests had such biological autoluminescence (BAL) recorded in controlled conditions, fostering applications for the non-invasive, real-time evaluation of a seedling's germinability and vigor when submitted to chemical and/or physical perturbations. However, long-term analysis of the BAL time-series of control samples conducted in different locations around the globe reveals that their BAL signals (and thus their metabolism) appear to follow the local gravimetric tide (g-tide) time profile. This indicates that the small daily and monthly variations in gravity acceleration due to the relative positioning of the Sun and Moon with respect to the Earth's surface influence these signals. The gravimetric tide is a natural phenomenon that affects all things, fluid or solid, and is an uncontrollable variable in normal laboratory settings on Earth's crust. All things on Earth have evolved under these pervasive cycles, with periods ranging from ~12.2 h up to 28 d, which correspond to the Moon cycle. Tide-like cycles occur in living beings of different types, from the simplest bacteria to the most complex human beings, and we speculate that water availability at the molecular level could be a significant physical factor in modulating bio-activity by enabling protein folding and all metabolic pathways that require a synchronized organization to adapt to external environmental conditions. In this study, we summarize published results of a seedling's BAL with cycle patterns resembling the g-tide in Limeira/BR, Prague/CZ, Leiden/NL, and Hamamatsu/JP and discuss the possible implications of this phenomenon for chronobiological studies. [ABSTRACT FROM AUTHOR]

Review of: Pacific Presences: Volume 1: Oceanic Art and European Museums, Lucie Carreau, Alison Clark, Alana Jelinek, Erna Lilje and Nicholas Thomas (eds) (2018) Leiden: Sidestone Press, 253 pp., ISBN 978 9 08890 589 6 (pbk), €45 Pacific Presences: Volume 2: Oceanic Art and European Museums, Lucie Carreau, Alison Clark, Alana Jelinek, Erna Lilje and Nicholas Thomas (eds) (2018) Leiden: Sidestone Press, 511 pp., ISBN 978 9 08890 626 8 (pbk), €85 [ABSTRACT FROM AUTHOR]

Accurate non-invasive biomarkers to diagnose metabolic dysfunction-associated steatotic liver disease (MASLD)-related fibrosis are urgently needed. This study applies a translational approach to develop a blood-based biomarker panel for fibrosis detection in MASLD. A molecular gene expression signature identified from a diet-induced MASLD mouse model (LDLr−/−.Leiden) is translated into human blood-based biomarkers based on liver biopsy transcriptomic profiles and protein levels in MASLD patient serum samples. The resulting biomarker panel consists of IGFBP7, SSc5D and Sema4D. LightGBM modeling using this panel demonstrates high accuracy in predicting MASLD fibrosis stage (F0/F1: AUC = 0.82; F2: AUC = 0.89; F3/F4: AUC = 0.87), which is replicated in an independent validation cohort. The overall accuracy of the model outperforms predictions by the existing markers Fib-4, APRI and FibroScan. In conclusion, here we show a disease mechanism-related blood-based biomarker panel with three biomarkers which is able to identify MASLD patients with mild or advanced hepatic fibrosis with high accuracy. Accurate non-invasive biomarkers to diagnose MASLD-related fibrosis are urgently needed. Here the authors show a disease mechanism-related blood-based biomarker panel consisting of three biomarkers which is able to accurately identify MASLD patients with mild or advanced hepatic fibrosis. [ABSTRACT FROM AUTHOR]