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1. Impact of Prior Infection and Age on Antibody Persistence After Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine.

Author

Fraley, Elizabeth, LeMaster, Cas, Khanal, Santosh, Banerjee, Dithi, Pastinen, Tomi, Grundberg, Elin, Selvarangan, Rangaraj, and Bradley, Todd

Subjects
*IMMUNOGLOBULINS, *COVID-19, *IMMUNIZATION, *GENETICS, *AGE distribution, *COVID-19 vaccines, *INFECTION, *MESSENGER RNA, *DESCRIPTIVE statistics, *DATA analysis software
Abstract

Determining the duration of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines is critical for informing the timing of booster immunization. Many genetic and environmental factors could influence both the magnitude and persistence of the antibody response. Here, we showed that SARS-CoV-2 infection before vaccination and age affected the decay of antibody responses to the SARS-CoV-2 messenger RNA vaccine. [ABSTRACT FROM AUTHOR]

Published
2022
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