Search

This paper presents an optimization procedure using tile stochastic model function, aiming at the application to the optimization of the circuit constant in the integrated circuit. The optimization of the circuit constant is formulated as a minimization problem for the objective function derived from the circuit response under the specified condition. In the method presented in this paper, the model function is constructed which approximates well the objective function, and the objective function is minimized by minimizing the model function. The features of the method are that the algorithm is simple, the number of evaluations of the objective function is small, the result depends less on the initial value, and the minimum of the objective function can be determined with a high accuracy. The method is evaluated using the standard test function, and it is verified that all minimum values of the objective function can be determined with n high accuracy with fewer number of calculations of the objective function. The optimization procedure is applied to two circuit examples: the analog control circuit and the inverter chain. The result is satisfactory and the usefulness of the presented optimization procedure in the circuit design is demonstrated. [ABSTRACT FROM AUTHOR]

Rubus chingii Hu, a member of the rosaceae family, is extensively distributed in China and Japan. Its unripe fruits (Fupenzi in Chinese) have a long history of use as an herbal tonic in traditional Chinese medicine for treating various diseases commonly associated with kidney deficiency, and they are still in use today. Phytochemical investigations on the fruits and leaves of R. chingii indicate the presence of terpenoids, flavonoids, steroids, alkaloids, phenylpropanoids, phenolics, and organic acids. Extracts or active substances from this plant are reported to have various pharmacological properties, including antioxidant, anti-inflammatory, antitumor, antifungal, antithrombotic, antiosteoporotic, hypoglycemic, and central nervous system-regulating effects. This review provides up-to-date information on the botanical characterizations, traditional usages, chemical constituents, pharmacological activities, toxicity, and quality control of R. chingii. Possible directions for future research are also briefly proposed. This review aims to supply fundamental data for the further study of R. chingii and contribute to the development of its clinical use., (Copyright © 2020 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.)