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Associations of sleep duration with human health could differ depending on whether sleep is restorative. Using data from 5804 participants of the Sleep Heart Health Study, we examined the longitudinal association of sleep restfulness combined with polysomnography-measured total sleep time (TST) or time in bed (TIB), representing different sleeping behaviors, with all-cause mortality. Among middle-aged adults, compared with restful intermediate TST quartile, the lowest TST quartile with feeling unrested was associated with higher mortality (hazard ratio [HR], 1.54; 95% confidence interval [CI] 1.01-2.33); the highest TST quartile with feeling rested was associated with lower mortality (HR, 0.55; 95% CI 0.32-0.97). Among older adults, the highest TIB quartile with feeling unrested was associated with higher mortality, compared with restful intermediate TIB quartile (HR, 1.57; 95% CI 1.23-2.01). Results suggest a role of restorative sleep in differentiating the effects of sleep duration on health outcomes in midlife and beyond., (© 2022. The Author(s).)

Objective: To clarify the prevalence of restless legs syndrome (RLS) in the chronic kidney disease (CKD) population and determine the relationship between severity of renal dysfunction and risk of RLS as well as the impact of the disorder on mood and sleep disturbance, we conducted a questionnaire survey followed by face-to-face interviews with Japanese CKD patients., Methods: We sent a questionnaire battery including demographics items, the National Institutes of Health/International RLS Study Group (IRLSSG) consensus questionnaire, the Center for Epidemiological Studies Depression Scale, and the Pittsburgh Sleep Quality Index to eligible CKD patients (n=514) and age- and sex-matched controls (n=535). Structured interviews were performed for the diagnosis of RLS., Results: The prevalence of positive RLS in the CKD subjects was significantly higher than that in the controls (3.5% vs. 1.5%, p=0.029). The proportion of renal failure (RF) in CKD subjects with RLS was significantly higher than in those without RLS, and multiple logistic regression analysis revealed that the presence of RLS symptoms was associated only with the existence of RF. In addition, the presence of both RLS and CKD was significantly associated with the presence of depression and sleep disturbance., Conclusions: The risk of RLS in the CKD population was higher than that in the general population and increased with the progression of renal dysfunction. Additionally, the existence of RLS might play a role in an increased risk for developing depression and sleep disturbance in the CKD population., (Copyright © 2011 Elsevier B.V. All rights reserved.)

Study Objectives: The present study was conducted to clarify the prevalence of non-pharmacological self-management (nPSM) practices for obtaining good sleep and to identify favorable nPSM practices that could be applied for reducing excessive daytime sleepiness (EDS). We analyzed epidemiological data for an authentic representative sample of the Japanese population., Methods: Data obtained from 24,686 adults via a self-administered questionnaire completed in the Active Survey of Health and Welfare 2000 were used for analyses. The prevalence of individual nPSM practices was calculated by gender. Subsequently, the associations between such practices and EDS were examined using logistic regression analyses., Results: "Having a bath" was the most prevalent nPSM practice for both men (59.0%) and women (64.4%), followed by "maintaining a regular schedule" (men: 49.0%, women: 58.6%), "reading or listening to music" (men: 43.4%, women: 49.4%), "snacking on food and/or beverages" (men: 36.1%, women: 27.9%), and "exercising" (men: 26.2%, women: 29.4%). The prevalence of "maintaining a regular schedule" increased with age. Multiple logistic regression analyses revealed that having a bath and maintaining a regular schedule had negative associations with EDS, whereas snacking on food and/or beverages had a positive association., Conclusions: Having a bath and maintaining a regular schedule were identified as favorable nPSM practices for reducing EDS, whereas snacking on food and/or beverages was considered to be an unfavorable nPSM practice.