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A retrospective study was conducted with patients involuntarily admitted to psychiatric hospitals. Patients were divided into the following two groups based on whether they had a history of legal proceedings before committing the act that subjected them to their current sentence: those who repeatedly harmed others (RHO) and those who did not (NRHO). We compared their characteristics and performed a two-variable logistic regression analysis. The total number of patients was 210. The RHO and NRHO groups included 51(24.3%) and 159(75.7%) patients. A comparison between the two groups revealed that patients in the RHO group were overwhelming male, with substance use and intellectual problems. The two-variable logistic regression analysis results indicated that the variables associated with RHO were "F1" and "a history of involuntary admission" in order of high odds ratios. The essential points regarding support for the RHO group were as follows: (1) intervention at the stages of initial criminal proceedings and involuntary admission, and (2) collaborative support between penal codes and the public health, medical, and welfare systems. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate real-world evidence for intraocular pressure (IOP) elevation after subtenon triamcinolone acetonide injection (STTA) in 1252 Japanese patients (1406 eyes) in the Japan Clinical REtina STudy group (J-CREST). Methods: This was a multicentre retrospective study of the medical records of 1252 patients (676 men (758 eyes); mean age: 63.8 ± 12.9 years) who received STTA in participating centres between April 2013 and July 2017. Results: IOP elevation was observed in 206 eyes (14.7%) and IOP increase ≥ 6 mmHg was found in 328 eyes (23.3%). In total, 106 eyes (7.5%) needed medication and two eyes (0.14%) needed surgical procedures. Younger age, higher baseline IOP, and steroid dose were risk factors associated with IOP elevation. Risk factors associated with IOP increase ≥ 6 mmHg were younger age, lower baseline IOP, steroid dose, and higher incidences of diabetic macular oedema (DME) and uveitis. In contrast, with steroid dose fixed at 20 mg, a lower incidence of DME was a risk factor for increased IOP, suggesting that STTA had dose-dependent effects on IOP increase, especially in patients with DME. Conclusion: Our real-world evidence from a large sample of Japanese patients who received STTA showed that the incidence of IOP elevation after STTA was 14.7%, and was associated with younger age, higher baseline IOP, and steroid dose. Thus, IOP should be monitored, especially in patients with younger age, higher baseline IOP, and higher incidences of DME and uveitis. [ABSTRACT FROM AUTHOR]

Details the fundus and fluorescein documentation of a Japanese boy with hypomelanosis. Presence of marked depigmentation in the retinal pigment epithelium.

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