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2 results on '"damage control"'

1. How does damage control strategy influence organ's suitability for donation after major trauma? A multi-institutional study.

Author

Altomare, Michele, Bekhor, Shir Sara, Sacchi, Marco, Ambrogi, Federico, Infante, Gabriele, Chieregato, Arturo, Pozzi, Federico, Feo, Tullia Maria De, Nava, Lorenza, Masturzo, Elisabetta, Prete, Luca Del, Perali, Carolina, Manzo, Elena, Bertoli, Paolo, Virdis, Francesco, Spota, Andrea, Cioffi, Stefano Piero Bernardo, Benuzzi, Laura, Santolamazza, Giuliano, and Podda, Mauro

Subjects
WOUNDS & injuries, STATISTICAL correlation, TRANSPLANTATION of organs, tissues, etc., CLUSTER analysis (Statistics), DATABASE management, SCIENTIFIC observation, KRUSKAL-Wallis Test, LOGISTIC regression analysis, ORGAN donation, PRESERVATION of organs, tissues, etc., SYMPTOMS, TREATMENT effectiveness, HOSPITALS, HOSPITAL emergency services, GLASGOW Coma Scale, CHI-squared test, DESCRIPTIVE statistics, LONGITUDINAL method, TRAUMA centers, ODDS ratio, TISSUE viability, RESEARCH, ELECTRONIC health records, MEDICAL records, ACQUISITION of data, ANALYSIS of variance, MACHINE learning, DATA analysis software, CONFIDENCE intervals
Abstract

The article focuses on the impact of damage control strategies on the suitability of organs for donation after major trauma. Topics include the role of trauma patients in organ donation, the effects of damage control surgery on organ viability, and the ongoing efforts to address organ shortages through improved donor selection and surgical techniques.

Published
2024
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2. Organ Donation after Damage Control Strategy in Trauma Patients: Experience from First Level Trauma Center in Italy.

Author

Altomare, Michele, Bekhor, Shir Sara, Cioffi, Stefano Piero Bernardo, Sacchi, Marco, Renzi, Federica, Spota, Andrea, Bini, Roberto, Ambrogi, Federico, Pozzi, Federico, Chieregato, Arturo, Chiara, Osvaldo, and Cimbanassi, Stefania

Subjects
*ORGAN donation, *PATIENTS' attitudes, *TRAUMA centers, *BRAIN death, *ORGAN donors, *LUNGS, *HEART transplantation, *PANCREAS
Abstract

Background: Organ donation (OD) remains the only therapeutic option for end-stage disease in some cases. Unfortunately, the gap between donors and recipients is still substantial. Trauma patients represent a potential yet underestimated pool of organ donors. In this article, we present our data on OD after damage control strategy (DCS). Materials and Methods: A retrospective, observational cohort study was conducted through a complete revision of data of consecutive adult trauma patients (>18 years old) who underwent OD after DCS between January 2018 and May 2021. Four subgroups were created [Liver (Li), Lungs (Lu), Heart (H), Kidneys (K)] to compare variables between those who donated the organ of interest and those who did not. Results: Thirty-six patients underwent OD after DCS. Six patients (16.7%) were excluded: 2(5.6%) for missing data about admission; 4(11.1%) didn't receive DCS. Mean ISS was 47.2 (SD ± 17.4). Number of donated organs was 113 with an organs/patient ratio of 3.8. The functional response rate was 91.2%. Ten organs (8.8%) had primary nonfunction after transplantation: 2/15 hearts (13.3%), 1/28 livers (3.6%), 4/53 kidneys (7.5%) and 3/5 pancreases (60%). No lung primary nonfunction were registered. Complete results of subgroup analysis are reported in supplementary materials. Conclusion: Organ donation should be considered a possible outcome in any trauma patient. Aggressive damage control strategy doesn't affect the functional response rate of transplanted organs. [ABSTRACT FROM AUTHOR]

Published
2022
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