1. Biomonitoring of polybrominated diphenyl ether (PBDE) pollution: a field study.
- Author
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Mariottini M, Corsi I, Della Torre C, Caruso T, Bianchini A, Nesi I, and Focardi S
- Subjects
- Animals, Benzopyrene Hydroxylase metabolism, Biomarkers metabolism, Cytochrome P-450 CYP1A1 metabolism, Halogenated Diphenyl Ethers, Italy, Liver drug effects, Microsomes, Liver drug effects, Microsomes, Liver enzymology, Phenyl Ethers toxicity, Pilot Projects, Polybrominated Biphenyls toxicity, Principal Component Analysis, Reproducibility of Results, Water Pollutants, Chemical toxicity, Anguilla metabolism, Environmental Monitoring methods, Liver enzymology, Muscles metabolism, Phenyl Ethers metabolism, Polybrominated Biphenyls metabolism, Water Pollutants, Chemical metabolism
- Abstract
Polybrominated diphenyl ethers (PBDEs) and cytochrome P450 enzyme activities were investigated in European eels (Anguilla anguilla) collected from seven sites in a coastal lagoon in the north-western Mediterranean Sea, Orbetello lagoon (Italy). Twelve PBDE congeners were measured in muscle and two CYP1A enzyme activities, 7-ethoxyresorufin-O-deethylase (EROD) and benzo(a)pyrene monooxygenase (BP(a)PMO), were investigated in liver microsomal fraction in order to obtain insights into the health of the lagoon environment. PBDE muscle levels were low and the most abundant congeners were 2,2',4,4'-tetrabromodiphenylether (BDE-47), 2,2',4,4',5,5'-hexaBDE (BDE-153) and 2,2',4,5'-tetraBDE (BDE-49). EROD and B(a)PMO activities were also low and no differences were observed between eels from different sites. Multivariate analysis (PCA) did not indicate correlations between PBDEs and either P450 activities.
- Published
- 2008
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