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What happens when five teacher candidates and their professor bring a wordless picturebook into Italian classrooms? This article presents a grounded discussion of our immersive experiences from the United States and the minilessons they taught stemming from a piece of children's literature through our study abroad program in Italy. The opening of Italian classroom doors provided reflective observations of the critical and creative thinking processes of more than 200 Italian students (ages 7-16). We (one professor and five early childhood and special education teacher candidates) taught minilessons in five Italian schools during a monthlong study abroad program offered by our university (further described in Author 1, 2017). Although this project was conducted in Italy, we have since used this minilesson successfully in our own classes, and we invite you to adapt our use to fit your teaching.

The aim of this article is to share the results of a research on personal characteristics and work behavior of innovators in Italy. The study was conducted following two phases, through the integrated use of quantitative and qualitative techniques. The results showed distinctive motivations, personality characteristics, and abilities of innovators: from risk-taking propensity to rejection of authority, to self-esteem. Moreover, the research analyzed innovators' work behaviors and described them through three main action patterns, from idea generation to idea promotion and implementation. By emphasizing the presence of certain contextual variables, such as gender and economic sector, the research aims to undermine the social representation that describes the innovator as a 'genius', in place of a vision in which innovation is a widespread quality of social action. [ABSTRACT FROM AUTHOR]

Objective: To identify children with postnatal hearing loss, a structured monitoring system is needed. The goal of this study was to describe a targeted surveillance program in Italy to identify children with postnatal hearing loss. Methods: Between January, 2013, and December, 2016, all children who received bilateral 'pass' result at the newborn hearing screening, and who were identified as having at least one risk factor, were referred for targeted surveillance. The hospital records of these children were retrieved. Results: Among children enrolled, 66 were identified with permanent hearing loss. The most frequent risk factors were family history (35%), prematurity (25.5%), low birthweight (19.2%), severe hyperbilirubinemia (19%), prolonged ventilation (15%) and congenital infection (12.5%). Conclusions: An audiological surveillance program in newborns who 'pass' in neonatal screening, but have risk factors, is effective in identifying permanent postnatal hearing disorders. [ABSTRACT FROM AUTHOR]

The aim of the article is to analyse the social transformations produced and observed in the field of waste management. In particular, the focus is on the «Zero Waste» strategy, which has been proposing for at least two decades at a global level an alternative model of waste governance to the one centred on incinerators and landfills. The article proposes a theoretical framework to describe the genesis of «Zero Waste» as a discursive practice, proposing to observe jointly its characteristic symbolic, technological and organisational elements. In reporting the results of an ethnographic research conducted on the case of «Zero Waste» in Italy, the article also focuses on the processes of knowledge exchange between social movements, local administrations, universities and municipalised companies, the conjunctions between ecological movements and movements for the commons, the start of processes of remunicipalisation of local public services starting from a new strategy of legitimation of the public vs. the private, and the progressive institutionalisation of political ecology in the European and local policy arena. [ABSTRACT FROM AUTHOR]

Since the outbreak of COVID-19 pandemic, the number of cases registered worldwide has risen to over 3 million. While COVID-19 per se does not seem to represent a significant threat to the pediatric population, which generally presents a benign course and a low lethality, the current emergency might negatively affect the care of pediatric patients and overall children welfare. In particular, the fear of contracting COVID-19 may determine a delayed access to pediatric emergency facilities. Present report focuses on the experience of The Children Hospital in Alessandria (northern Italy). The authors document a drop in the number of admissions to the emergency department (A&E) during the lock-down. They will also focus on four emblematic cases of pediatric patients who were seen to our A&E in severe conditions. All these cases share a significant diagnostic delay caused by the parents' reluctance to seek medical attention, seen as a potential risk factor for COVID-19 contagion. None was found positive to all COVID-19 swab or immunologic testing. All in all, our data strongly support the importance of promoting a direct and timely interaction between patients and medical staff, to prevent the fear of COVID-19 from causing more harm than the virus itself. [ABSTRACT FROM AUTHOR]

Several surveys and clinical studies report high prevalence of work-related musculoskeletal disorders (WMSDs) among sonographers and sonologists. Better performing ultrasound devices can increase the number and quality of examinations, but also reduce the user comfort and increase the risk of WMSDs. This should lead the choice of the device to buy and use. To support hospitals or diagnostic centres in selecting the best ultrasound device, this study provides a structured methodology based on a multi-criteria approach, the Analytic Hierarchy Process. It has a Goal (to optimise workers' well-being and satisfy company production objectives) and 45 evaluation elements. It was applied in an Italian hospital comparing 3 alternatives: wireless, portable, and cart-based. The latter proved to be the best in satisfying the Goal, whereas a previous study obtained that the wireless device was preferable considering only the ergonomic point of view. The case study validated the applicability of the methodology. Practitioner summary: This paper provides the decision-makers of hospitals or diagnostic centres with a multi-criteria methodology to select the best ultrasound device capable of optimising workers' well-being and satisfying company production objectives. The methodology can also support manufacturers of ultrasound devices in improving their products. Abbreviations: AHP: analytic hierarchy process; AIUM: American Institute of Ultrasound in Medicine; BSI: British Standards Institution; CEN: European Committee for Standardisation; EU-OSHA: EU Agency for Occupational Safety and Health; ISO: International Organisation for Standardisation; MCMD: multiple criteria decision-making; NIOSH: US National Institute for Occupational Safety and Health; SDMS: society of diagnostic medical sonography; WHO: World Health OrganizationWMSD: work-related musculoskeletal disorder [ABSTRACT FROM AUTHOR]

Background: From 2011 to 2014, a total of 71% of the 3834 patients with hematologic malignancies successfully identified a matched unrelated donor (MUD) through the Italian Bone Marrow Donor Registry (IBMDR), corresponding to a transplant efficiency of 62%.Study Design and Methods: From 2006, the Rome Transplant Network (RTN) followed a hierarchical selection strategy for the alternative donor search: first MUD, second cord blood, and third haploidentical donor. Using a low-resolution HLA, a preliminary query (PQ) was performed in all cases with assignment of good or poor score if more or less than 10 MUDs were identified in Bone Marrow Donors Worldwide. Herein we assessed the utility of PQ and of high-resolution (HR) HLA from the start of the search. Moreover, we compared the donor identification and the transplant efficiency between IBMDR and RTN.Results: At RTN 79% of 417 patients met a good PQ with a 50% MUD identification versus 12.5% with poor PQ. Our policy led to 78 and 74% of alternative donor identification and transplant efficiency, respectively, higher than IBMDR data equal to 71% (p = 0.007) and 62% (p < 0.0001). The timing for donor identification was significantly reduced using HR HLA at the start of the search from 88 to 66 days at IBMDR (p < 0.001) and from 61 to 41 days at RTN (p < 0.001).Conclusions: Both PQ and HR HLA at the start of the process represents a useful tool to address the search towards the best and timely donor choice. Moreover, establishing a specific donor policy significantly improves the transplant efficiency. [ABSTRACT FROM AUTHOR]

The article discusses the analysis of the SLC26A4 gene of 30 Italian children with severe-to-profound congenital sensorineural hearing loss (SNHL). It states the identification of 10 independent mutated alleles and another variant p.I655V that is indicated as pathogenic only in gene-specific mutation/SNP databases. It mentions that mutation of SLC26A4 is relevant cause of deafness.

The percentage of forest fires of unknown origin, accounting in Italy for about 40% of the total number, hampers any attempt of efficacious prevention based on modification of causes. This work deals with the implementation of a simple though promising technique of motivation survey aimed at reducing such percentage, the Delphi method, a grouping technique using estimates from a panel of experts and feedback summaries from preceding responses for additional estimates. Sitting between knowledge and speculation, the informed deliberations of the panel of experts may be considered an informed judgment. Delphi surveys were carried out by CFS (National Forestry Service) in 23 of the most affected provinces, involving several panel of experts for a total of 1000 people, all of them on duty in the Forestry Stations of the Service. Results highlighted a remarkable prevalence of involuntary versus voluntary fires (54% and 42%, respectively). The panels of experts provided fairly homogeneous and convergent answers based on few motives, the majority of fire ignitions were attributed to: (i) creation or renewal of pastures; (2) residues elimination, including stubble burning; (iii) increasing the yield of wild plant foods; (iv) poaching probably related to limitation of hunting use and access control. The most recurrent motivations represent traditional uses of fire by rural societies. Other motivations presented less significant and negligible values. Cluster analysis clearly put in evidence that similar motivations characterize small and homogeneous groups of provinces, supporting the evidence that fire motivations are site and culture specific phenomena. [ABSTRACT FROM AUTHOR]

Abstract Objective: To determine the incidence of GJB2 and GJB3 mutations and of two deletions upstream of the GJB6 gene in infants of the Campania region of southern Italy. Design : DNA samples from non-syndromic hearing-impaired infants enrolled in a neonatal screening programme for sensorineural hearing loss were analysed by PCR and by direct sequencing. The audiological features of infants with biallelic GJB2 mutations were also examined to identify genotype-phenotype correlations. Study sample : Molecular analyses were carried out in 129 affected and five unaffected infants. Results: A genetic etiology of hearing loss was identified in 28% of infants, including several at environmental risk of hearing loss. Neither GJB6 nor GJB3 (a gene not previously investigated in the Campania population) mutations were found. Conclusions: This study confirms the importance of universal neonatal hearing screening. The identification of a genetic cause in infants at environmental risk indicates that such infants should be included when investigating etiology. We confirm that also in our geographical area, c.35delG homozygotes tend to have severe symmetrical hearing loss, whereas hearing impairment is milder in compound heterozygotes. Sumario Objetivo: Determinar la incidencia de mutaciones GJB2 y GJB3 y de dos deleciones corriente arriba en el gen GJB6 en niñosde la región de Campania en el sur de Italia. Diseño: Se analizaron por PCR y por secuenciación directa muestras de ADN de niños con trastornos auditivos no sindrómicos incluidos en el programa de tamiz neonatal para hipoacusias sensorineurales. Los rasgos audiológicos de niños con mutaciones bi-alélicas del GJB2 también se examinaron para identificar correlaciones genotípicas y fenotípicas. Muestra del Estudio: Se realizó un análisis molecular en 129 niños afectados y en 5 no afectados. Resultados: Se identificó una etiología genética de la sordera en 28% de los infantes, incluyendo varios con riesgo ambiental de hipoacusia. No se encontraron mutaciones en el gen GJB6 o en el GJB3 (un gene no investigado previamente en la población de Campania). Conclusiones: Este estudio confirma la importancia del tamiz auditivo neonatal universal. La identificación de una causa genética en niños con un riesgo ambiental indica que tales infantes deberían incluirse cuando se investiga la etiología. Confirmamos que también en nuestra área geográfica, los homocigotos c.35delG tienden a tener hipoacusias simétricas severas, mientras que el trastorno auditivo es más leve en heterocigotos compuestos. [ABSTRACT FROM AUTHOR]

Chemical and petrochemical wastewaters contain a host of contaminants that require different treatment strategies. Regulation of macropollutants and micropollutants in the final discharge from industrial wastewater treatment plants (WWTPs) have become increasingly stringent in recent decades, requiring many WWTPs to be upgraded. This article presents an analysis of a WWTP treating petrochemicals in Porto Marghera, Italy, that recently was upgraded following legislative changes. Because of strict legal limits for macropollutants and micropollutants and a lack of space necessary for a full-scale WWTP overhaul, the existing activated sludge tank was converted into a membrane biological reactor. The paper presents experimental data collected during a five-month investigation showing the removal rates achieved by the upgraded plant for macropollutants (particularly nitrogen compounds) and micropollutants (heavy metals and organic and inorganic toxic compounds). Water Environ. Res., 83, 739 (2011). [ABSTRACT FROM AUTHOR]

Abstract The aim of this study was to screen 349 patients affected by sensorineural hearing loss (SNHL), mostly from the Campania region (southern Italy), for GJB2 gene mutations and for two deletions of the GJB6 gene (del GJB6 -D13S1830 and del GJB6 -D13S1854). We identified pathogenetic GJB2 mutations in 51 cases (15% of patients). No GJB6 mutation was found. We also examined the audiologic features of the patients for whom we had an etiologic diagnosis, in order to identify correlations between the severity of hearing loss and the type of mutation. Sumario El objetivo de este estudio fue evaluar 349 pacientes afecta-dos de una hipoacusia sensorineural (SNHL), sobre todo de la región de Campania (Italia del sur), buscando muta-ciones en el gen GJB2 y dos deleciones en el gen GJB6 (del GJB6-D13S1830 y del GJB6-13S1854). Identifica-mos mutaciones patogénicas en 51 pacientes (15% de los pacientes). No se encontraron mutaciones del gen GJB6. También examinamos los rasgos audiológicos de aquellos pacientes de quienes teníamos diagnóstico etiológico, para identificar correlaciones entre la severidad de la pérdida audi-tiva y el tipo de mutación. [ABSTRACT FROM AUTHOR]

The objective of this study was to estimate the prevalence of hearing impairment in four genetically isolated Italian villages (Carlantino, Campora, Gioi-Cardile, and Stoccareddo), 1682 subjects were recruited from all the individuals participating in a multidisciplinary study. They underwent otoscopy and pure-tone audiometry and completed a questionnaire. The audiological data show that the percentage of impaired people increases with age and in particular becomes relevant aged over 40. For this reason we decided to compare the PTA values of individuals aged 40 or older. The PTA values of Stoccareddo and Carlantino are statistically different from PTAs of the other villages. Campora and Gioi-Cardile, both located within the Cilento National Park, have similar middle-low frequency PTA values while some differences are present at high frequencies. Using pedigrees it was possible to calculate the heritability of the trait. For Carlantino and Gioi-Cardile the percentage of the phenotype variation attributable to genetic variation is not significant, while for Campora the heritability value is 0.49 (p = 0.01) suggesting that genetic factors may have an important role. [ABSTRACT FROM AUTHOR]

Background: A significant proportion of patients with coronavirus disease 2019 (COVID-19) suffer from delirium during hospitalization. This single-center observational study investigates the occurrence of delirium, the associated risk factors and its impact on in-hospital mortality in an Italian cohort of COVID 19 inpatients. Methods: Data were collected in the COVID units of a general medical hospital in the South of Italy. Socio-demographic, clinical and pharmacological features were collected. Diagnosis of delirium was based on a two-step approach according to 4AT criteria and DSM5 criteria. Outcomes were: dates of hospital discharge, Intensive Care Unit (ICU) admission, or death, whichever came first. Univariable and multivariable proportional hazards Cox regression models were estimated, and risks were reported as hazard ratios (HR) along with their 95% confidence intervals (95% CI). Results: A total of 47/214 patients (22%) were diagnosed with delirium (21 hypoactive, 15 hyperactive, and 11 mixed). In the multivariable model, four independent variables were independently associated with the presence of delirium: dementia, followed by age at admission, C-reactive protein (CRP), and Glasgow Coma Scale. In turn, delirium was the strongest independent predictor of death/admission to ICU (composite outcome), followed by Charlson Index (not including dementia), CRP, and neutrophil-to-lymphocyte ratio. The probability of reaching the composite outcome was higher for patients with the hypoactive subtype than for those with the hyperactive subtype. Conclusions: Delirium was the strongest predictor of poor outcome in COVID-19 patients, especially in the hypoactive subtype. Several clinical features and inflammatory markers were associated with the increased risk of its occurrence. The early recognition of these factors may help clinicians to select patients who would benefit from both non-pharmacological and pharmacological interventions in order to prevent delirium, and in turn, reduce the risk of admission to ICU or death. [ABSTRACT FROM AUTHOR]

This paper deals with the case of one of the most important industrial application of membrane technology in the world: the upgrading of the main industrial wastewater treatment plant (WWTP) of the petrochemical site of Porto Marghera, Northern Italy, completed on December 2005 and tested on September 2006. It describes the principal interventions of the plant upgrading and it discusses the removal obtained during the test periods for conventional pollutants as well as for micropollutants. The plant upgrading consisted of a series of improvements of the existing industrial WWTP, in order to increase the removal efficiency of the total suspended solids and the associate removal of ten micropollutant compounds, the so called forbidden substances. The most important intervention was the conversion of the existing activated sludge section into a membrane biological reactor, in order to guarantee adherence to the severe limits imposed by the special law issued to protect the Venice Lagoon, with particular reference to the mentioned 10 forbidden compounds. The experimental results and the numerous test-runs conducted confirmed the respect of the legal limits for the pollutants in the final effluent as well of the required removal rates for the different parameters. Therefore, the upgraded treatment plant was declared agreeing with the approved design. [ABSTRACT FROM AUTHOR]

Abstract: The results of stratigraphic and tephrostratigraphic analyses of several pyroclastic levels, collected along the coastal sector of the Cilento region (southern Italy), are presented. Some of these levels are here described for the fist time, others, already known in literature, were reconsidered in order to better understand their stratigraphic position and to point out the possible volcanic sources. The main outcrops are located along the southern coast of the Campania region (Cilento coast). All pyroclastic layers are interbedded within coastal or continental successions younger than the substage 5e of the Last Interglacial (<130 ka) or cover erosional coastal morphologies belonging to the same period. Only in one site the sampled tephra can be considered older. As a consequence, the age range for their emplacement is constrained to the last 200 ka. The results of SEM-EDS analyses on well preserved glass fragments indicate a composition falling between the trachyte and phonolite fields of the TAS plot, as typical of Phlaegrean Fields products. By comparing their composition with those of the main tephra marker layers recorded in southern Italy, the correlation of the Cilento pyroclastic layers with well known eruptive episodes was hypothesised. In summary, four different eruptions were recognised. The first one is testified by a pyroclastic layer, not correlated with a terrestrial counterpart, covered by a Middle Pleistocene alluvial fan, the second one is the eruptive event emplacing the X-6 marker tephra layer, and dates around 107 ka, the third is the Campanian Ignimbrite eruption (39 ka), and the last one is testified by the layers correlated with the Y-3 tephra (about 30 ka). These pyroclastic layers can be useful tools for stratigraphic correlations of Late Quaternary successions in southern Italy. [Copyright &y& Elsevier]

An overview of a lecture presentation on the use of hearing aids in older people at de Senectute: Age and Health Forum in Catanzaro, Italy from December 5 to 7, 2009 is presented. It is said that 20% of people with prebyacusis use hearing aids while 25-40% of them do not use or do not regularly use them. The lecture examined the reasons why such patients are reluctant to wear hearing aids and the technical solutions on fitting hearing-aid to older patients. Rehabilitation issues for patients with multi-sensorineural impairment were also addressed.

Abstract: Aim: To describe the effectiveness of a population-based newborn hearing screening program in an economically deprived region of southern Italy. Methods: A screening protocol was proposed for all newborns of the Campania region, starting on January, 2007. For infants identified with hearing loss, information on degree and type of hearing loss and presence of risk factors was collected. Results: The infants born in the 3-year study period were 182,188. Among them, 146,026 (80%) were tested with OAE. Sensorineural hearing loss ≥40dBnHL was established for 159 infants (1.1×1000). Among the NICU and WIN infants, the rate of hearing loss was respectively 9×1000 and 0.67×1000. Follow-up information was available for 111 children (70%), as 48 (30%) got care in other regions or health facilities. Most infants were fitted hearing aids by 1 month after diagnosis and 15 children (13.5%) received a cochlear implant at a mean age of 25 months (SD 10). Conclusions: Even in a setting of population poverty, a universal newborn screening program can deliver satisfactory outcomes. The coverage and the tracking system of the program need to be improved, as well as the cooperation between public and private health services. [Copyright &y& Elsevier]