Costantino, Giorgio, Furlan, Ludovico, Bracco, Christian, Cappellini, Maria Domenica, Casazza, Giovanni, Nunziata, Vanessa, Cogliati, Chiara Beatrice, Fracanzani, Anna, Furlan, Raffaello, Gambassi, Giovanni, Manetti, Roberto, Manna, Raffaele, Piccoli, Alfonso, Pignone, Alberto Moggi, Podda, GianMarco, Salvatore, Teresa, Sella, Stefania, Squizzato, Alessandro, Tresoldi, Moreno, and Perticone, Francesco
• Less is More and Choosing Wisely (CW) campaigns have raised awareness about inappropriate diagnostic procedures and therapeutic approaches among both physicians and patients. • Little is currently known about the effects of Choosing Wisely recommendation-driven educational programs on clinical practice. • The CW-SIMI study evaluated the impact of a simple educational program, based on the Italian Society of Internal Medicine (SIMI) Choosing Wisely recommendations, on clinical practice in internal medicine units. • The proposed online educational intervention effectively reduced the proton pump inhibitor (PPI) prescription rate and the mean duration of central venous catheter (CVC) usage. To evaluate the impact of an educational intervention based on the Italian Society of Internal Medicine Choosing Wisely (CW-SIMI) recommendations. Multicenter, interventional, controlled study. Twenty-three acute-care hospital wards in Italy. 303 Physicians working in internal medicine wards. An online educational course. The rate of proton pump inhibitor (PPI) prescriptions, the number of days of central venous catheter (CVC) usage, and the duration of intravenous (IV) antibiotic prescriptions evaluated at one month (T1) and at six months (T2) after course completion. Patients admitted and discharged during a 30-day period before the educational intervention (T0, one year before T2) were considered the comparison group. A total of 232 physicians completed the course, while 71 did not attend the course. Data from 608, 662, and 555 patients were analyzed at T0, T1, and T2, respectively. The rate of PPI prescriptions declined at one month (RR: 0.67, 95% CI: 0.52–0.87, p = 0.0005) and at six months (RR: 0.62, 95% CI: 0.46–0.84, p = 0.003), and the number of days of CVC usage was reduced at six months (9.13 days at T0 vs. 5.52 days at T2, p = 0.007). The duration of IV antibiotic prescriptions displayed a decreasing trend (7.94 days at T0 vs. 7.42 days at T2, p = 0.081). A simple online educational intervention based on the CW-SIMI recommendations was associated with a clinically relevant reduction in the usage of PPIs and CVCs. Further studies are needed to confirm these findings and a possible benefit on patients' outcomes. [ABSTRACT FROM AUTHOR]