1. A retrospective study on the efficacy of short-term perioperative prophylaxis in abdominal surgery for hernia repair in 1,254 patients.
- Author
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Gervino L, Cangioni G, and Renzi F
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Antibiotic Prophylaxis economics, Ceftriaxone administration & dosage, Drug Administration Schedule, Female, Humans, Incidence, Infusions, Intravenous, Italy epidemiology, Male, Middle Aged, Retrospective Studies, Antibiotic Prophylaxis statistics & numerical data, Ceftriaxone therapeutic use, Herniorrhaphy, Surgical Wound Infection epidemiology, Surgical Wound Infection prevention & control
- Abstract
Between 1992 and 1999 1,254 patients requiring hernioplasty came to our Department of Surgery, at San Giovanni Valdarno Hospital, Arezzo. In 94% of cases a prosthetic device was inserted. All patients received a preoperative antibiotic prophylaxis with ceftriaxone, administered intravenously in a single 2 g dose, before surgery. We have retrospectively evaluated the incidence of postoperative infections in these patients: no surgical wound infection occurred, while we observed 10 cases of systemic infections, 5 respiratory tract infections and 5 urinary tract infections, all of which were successfully treated with antibiotics. Tolerability was good: no adverse reaction to ceftriaxone was observed. In this retrospective study ceftriaxone was shown to be effective in preventing the onset of postoperative infections.
- Published
- 2000
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