35 results on '"Conti, C."'
Search Results
2. The last cave lion of the late Upper Palaeolithic: The engraved feline of Grotta Romanelli (southern Italy).
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Sigari, D., Bourdier, C., Conti, C., Conti, J., Forti, L., García-Diez, M., Lai, G., Mazzini, I., Pieruccini, P., and Sardella, R.
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PALEOLITHIC Period , *ART objects , *LIONS , *RAW materials , *INTERDISCIPLINARY education , *FELIDAE , *STONE - Abstract
On the occasion of the review of the portable art of Grotta Romanelli, a decorated stone with a feline figure was object of an interdisciplinary study. The analysis considered different approaches so to: characterise the stratigraphic setting of the finding, the rock support, look into the techniques used to decorate the stone, elaborate a graphic documentation (photographs, 3D models and tracings), relate the symbolic production with the environmental context, and consider the motifs into the wider late Upper Palaeolithic (LUP) art production. The work allows confirming that the represented subject corresponds to a Panthera spelaea , and fixing some issues concerning the variability of the decorating activity, which is in line with the graphic tradition of the European LUP. Style and formal variable features of the figure might have responded to specific social conventions or to single author's skills, tracing new investigation lines about the cultural behaviour and the decorating activity: from the collection of the raw material and the preliminary modelling of the support, to the different artistic techniques (engraving and painting), from the use of the object to the definition of possible local artistic variations and/or inspiration at large scale. Moreover, it questions the thematic aspect in relation to the local fauna and its influence in the symbolic production, highlighting the importance of this stone in the wider debate about the extinction of the cave lions. Indeed, the Romanelli lion may represent the last evidence of this animal in Europe. • One of the richest records of Palaeolithic portable art of Italy. • Interdisciplinary approach to the study of a portable art object. • The engraved lion of Grotta Romanelli and the extinction of P. spelaea in Europe. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Clostridium difficile 027 increasing detection in a teaching hospital in Rome, Italy.
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Orsi, G., Conti, C., Mancini, C., and Giordano, A.
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FECAL analysis ,ACADEMIC medical centers ,CLOSTRIDIOIDES difficile ,CLOSTRIDIUM diseases ,CROSS infection ,POLYMERASE chain reaction ,RETROSPECTIVE studies ,DESCRIPTIVE statistics - Abstract
A letter to the editor is presented in response to the article related to lethal fulminant healthcare-associated Clostridium difficile colitis, published in the previous issue.
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- 2014
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4. Off-Label Use of Intravenous Immunoglogulins (IVIGS): Funding Mechanisms in France, Germany, Italy, Spain and the United Kingdom (EU5).
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Charafi, N, Gauthier Darnis, M, Conti, CC, and Conti, C C
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OFF-label use (Drugs) , *INTRAVENOUS immunoglobulins , *PUBLIC health - Published
- 2015
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5. PainRE-Life: A FHIR Based Telemonitoring Ecosystem for the Management of Patients with Chronic Pain.
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Marceglia S, Manzelli V, Caruso A, Prenassi M, Prandin R, Savino C, Tacconi D, Ferrucci R, Conti C, Candiani G, Toraldo C, Judica E, Corbo M, Masiero M, and Pravettoni G
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- Humans, Data Management, Italy, Chronic Pain diagnosis, Chronic Pain therapy, Electronic Health Records
- Abstract
Chronic pain is a condition in which the use of digital health technologies, ecological momentary assessments, and digital communication tools may boost patient's engagement and coping. Here we present the results of the PainRE-Life a project, financed by the Lombardy Region (Italy), aimed to develop a dynamic and integrated technology ecosystem based on big data management and analysis to allow care continuity in patients with pain, and able to act as a decision aid for patients and caregivers.
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- 2023
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6. Integrating conventional and complementary treatments in cancer care: The process within the public healthcare system of the region of Tuscany, Italy.
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Giovanni RE, Francesca B, Anna N, Cristina N, Marco P, Linda N, Pasquale GC, Fabio F, Rosaria F, Franco C, Mariella DS, Tommaso C, Chiara M, Irene S, Sonia B, Luigi S, Filippo B, Francesca M, Cristina P, Alessandra S, Enrico T, and Gianni A
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- Humans, Italy, Delivery of Health Care, Neoplasms therapy
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Competing Interests: Declaration of competing interest The Authors declare that they have no competing interests. All the costs for this study were supported by the Region of Tuscany.
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- 2023
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7. [The influence of COVID-19 pandemic on migratory flows towards Italy and on integration paths of immigrants].
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Prati S and Conti C
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- Adolescent, Child, Demography, Developed Countries, Europe, Humans, Italy epidemiology, Pandemics, Population Dynamics, COVID-19 epidemiology, Emigrants and Immigrants, Transients and Migrants
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The text describes the effects of the pandemic on the dynamics of migration flows from abroad to Italy in 2020. The composition and demographic structure of the population of foreign origin are described in order to understand which areas of immigration and integration are most affected by the pandemic.It has been observed that, although the downward trend in migration flows predates the spread of COVID-19, the pandemic has led to a drastic decrease in migration flows towards our country, where a stable foreign presence has settled over the years. The transformation of Italy into a country of stable integration is also witnessed by the growing number of foreigners who become Italian through the acquisition of citizenship, a process that not even the pandemic has slowed down. Instead, the possible effects of the pandemic on economic and labour integration and inclusion, particularly of the many children and young people of foreign origin living in our country, are worrying.
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- 2022
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8. Incidence and spatial distribution of adult-onset primary malignant and other central nervous system tumors in Southern Sardinia, Italy.
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Pierri V, Dagostino S, Vasta R, Ercoli T, Piga G, Melas V, Bruder F, Conti C, Cappai PF, Manieli C, Melis M, Floris G, Melis M, Muroni A, Maleci A, and Defazio G
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- Adolescent, Adult, Humans, Incidence, Italy epidemiology, Male, Brain Neoplasms, Central Nervous System Neoplasms epidemiology, Meningeal Neoplasms
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Purpose: To study for the first time the incidence of adult-onset CNS tumors in Southern Sardinia, Italy., Methods: Clinical records of patients > 18 years old who were diagnosed with primary CNS tumors during 2016-2019 in the study area were reviewed. Meningiomas, cranial/paraspinal nerve tumors, lymphomas, and pituitary tumors were excluded. Cases were classified according to the 2016 WHO classification of CNS tumors and to the morphology codes from the International Classification of Diseases-Oncology, third edition. Age-adjusted incidence rates were calculated by the direct method to the 2011-2020 European standard population. Kulldorff's spatial scan statistic was used to identify geographic clusters of patients who shared increased/decreased tendency to develop CNS tumors., Results: CNS tumors were diagnosed in 234 incident patients, but histological diagnosis was available in 222/234 patients (95%) aged 64.3 ± 13.5 years at diagnosis. Crude incidence rate was 7.1 per 100,000 persons-year (95% CI, 6.2-8.1), 6.2 per 100,000 persons-year (95% CI, 5.4-7.0) when age-adjusted. CNS tumors were more frequent in men and after age 40. Glioblastoma accounted for 76% of the total (adjusted rate, 4.7 per 100,000 persons-year; 95% CI, 4.0-5.4). Spatial analysis revealed geographic variations of glioblastoma incidence within the study area., Conclusion: Although the distribution of tumor diagnoses in Sardinia reflects expected age and gender-related patterns in western populations, our findings would indicate a slightly higher incidence of glial tumors, glioblastoma in particular, in Sardinia than in other European countries. The identification of spatial clusters of high/low risk will serve as a resource for etiological research., (© 2021. Fondazione Società Italiana di Neurologia.)
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- 2022
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9. Evaluation of the Psychometric Properties of the Scale A-ONE: An Italian Cross-Sectional Study.
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Cerone M, Tofani M, Fabbrini G, Marcellini G, Berardi A, Conti C, De Santis R, Valente D, and Galeoto G
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- Aged, Aged, 80 and over, Cross-Sectional Studies, Disability Evaluation, Female, Humans, Italy, Male, Middle Aged, Reproducibility of Results, Task Performance and Analysis, Activities of Daily Living, Cerebrovascular Disorders rehabilitation, Neuropsychological Tests standards, Psychometrics statistics & numerical data, Surveys and Questionnaires standards
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Purpose: This study is aimed at validating the A-ONE scale in an Italian population with Central Nervous System (CNS) dysfunction. Material and Methods . Between May and November 2018, people aged between 60 and 90 with CNS dysfunction were recruited in a hospital in Rome, Italy. Patients were observed and evaluated during the activities of daily living. Internal consistency and reliability were evaluated with Cronbach's coefficient alpha and intraclass correlation coefficient, respectively. As measured with Pearson's correlation coefficient, the validity was examined comparing results of the A-ONE with the Barthel index. Responsiveness was evaluated 30 days after the first administration., Results: A total of 70 people having a diagnosis of neurological disorders were evaluated. The internal consistency showed Cronbach's coefficient alpha ranging from 0.634 to 0.959. The measurement of reliability varied from 0.984 to 0.997 for intrarater and from 0.979 to 0.998 for interrater. Pearson's correlation coefficient between the A-ONE and the Barthel index and the responsiveness showed statistically significant values ( p < 0.01)., Conclusions: The present study provides preliminary evidence of reliability, validity, and responsiveness of the A-ONE when using elderly people with CNS dysfunction., Competing Interests: All authors declare no conflict of interest., (Copyright © 2021 Margherita Cerone et al.)
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- 2021
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10. At the peak of COVID-19 age and disease severity but not comorbidities are predictors of mortality: COVID-19 burden in Bergamo, Italy.
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Novelli L, Raimondi F, Ghirardi A, Pellegrini D, Capodanno D, Sotgiu G, Guagliumi G, Senni M, Russo FM, Lorini FL, Rizzi M, Barbui T, Rambaldi A, Cosentini R, Grazioli LS, Marchesi G, Sferrazza Papa GF, Cesa S, Colledan M, Civiletti R, Conti C, Casati M, Ferri F, Camagni S, Sessa M, Masciulli A, Gavazzi A, Falanga A, DA Pozzo LF, Buoro S, Remuzzi G, Ruggenenti P, Callegaro A, D'Antiga L, Pasulo L, Pezzoli F, Gianatti A, Parigi P, Farina C, Bellasi A, Solidoro P, Sironi S, DI Marco F, and Fagiuoli S
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- Adult, Aged, Aged, 80 and over, COVID-19 complications, COVID-19 mortality, Female, Humans, Italy epidemiology, Male, Middle Aged, Retrospective Studies, SARS-CoV-2 isolation & purification, Severity of Illness Index, Age Factors, COVID-19 epidemiology, COVID-19 pathology
- Abstract
Background: Findings from February 2020, indicate that the clinical spectrum of COVID-19 can be heterogeneous, probably due to the infectious dose and viral load of SARS-CoV-2 within the first weeks of the outbreak. The aim of this study was to investigate predictors of overall 28-day mortality at the peak of the Italian outbreak., Methods: Retrospective observational study of all COVID-19 patients admitted to the main hospital of Bergamo, from February 23 to March 14, 2020., Results: Five hundred and eight patients were hospitalized, predominantly male (72.4%), mean age of 66±15 years; 49.2% were older than 70 years. Most of patients presented with severe respiratory failure (median value [IQR] of PaO
2 /FiO2 : 233 [149-281]). Mortality rate at 28 days resulted of 33.7% (N.=171). Thirty-nine percent of patients were treated with continuous positive airway pressure (CPAP), 9.5% with noninvasive ventilation (NIV) and 13.6% with endotracheal intubation. 9.5% were admitted to Semi-Intensive Respiratory Care Unit, and 18.9% to Intensive Care Unit. Risk factors independently associated with 28-day mortality were advanced age (≥78 years: odds ratio [OR], 95% confidence interval [CI]: 38.91 [10.67-141.93], P<0.001; 70-77 years: 17.30 [5.40-55.38], P<0.001; 60-69 years: 3.20 [1.00-10.20], P=0.049), PaO2 /FiO2 <200 at presentation (3.50 [1.70-7.20], P=0.001), need for CPAP/NIV in the first 24 hours (8.38 [3.63-19.35], P<0.001), and blood urea value at admission (1.01 [1.00-1.02], P=0.015)., Conclusions: At the peak of the outbreak, with a probable high infectious dose and viral load, older age, the severity of respiratory failure and renal impairment at presentation, but not comorbidities, are predictors of 28-day mortality in COVID-19.- Published
- 2021
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11. Surviving COVID-19 in Bergamo province: a post-acute outpatient re-evaluation.
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Venturelli S, Benatti SV, Casati M, Binda F, Zuglian G, Imeri G, Conti C, Biffi AM, Spada MS, Bondi E, Camera G, Severgnini R, Giammarresi A, Marinaro C, Rossini A, Bonaffini PA, Guerra G, Bellasi A, Cesa S, and Rizzi M
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- Adult, Aftercare, Aged, Aged, 80 and over, COVID-19 complications, Female, Hospitalization, Humans, Italy epidemiology, Male, Middle Aged, Patient Discharge, Polymerase Chain Reaction, RNA, Viral blood, Severity of Illness Index, Young Adult, COVID-19 mortality, COVID-19 pathology, SARS-CoV-2
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Bergamo province was badly hit by the coronavirus disease 2019 (COVID-19) epidemic. We organised a public-funded, multidisciplinary follow-up programme for COVID-19 patients discharged from the emergency department or from the inpatient wards of 'Papa Giovanni XXIII' Hospital, the largest public hospital in the area. As of 31 July, the first 767 patients had completed the first post-discharge multidisciplinary assessment. Patients entered our programme at a median time of 81 days after discharge. Among them, 51.4% still complained of symptoms, most commonly fatigue and exertional dyspnoea, and 30.5% were still experiencing post-traumatic psychological consequences. Impaired lung diffusion was found in 19%. Seventeen per cent had D-dimer values two times above the threshold for diagnosis of pulmonary embolism (two unexpected and clinically silent pulmonary thrombosis were discovered by investigating striking D-dimer elevation). Survivors of COVID-19 exhibit a complex array of symptoms, whose common underlying pathology, if any, has still to be elucidated: a multidisciplinary approach is fundamental, to address the different problems and to look for effective solutions.
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- 2021
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12. Describing the trend of ammonia, particulate matter and nitrogen oxides: The role of livestock activities in northern Italy during Covid-19 quarantine.
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Lovarelli D, Conti C, Finzi A, Bacenetti J, and Guarino M
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- Ammonia analysis, Animals, Betacoronavirus, COVID-19, Cities, Environmental Monitoring, Humans, Italy, Livestock, Nitrogen Oxides analysis, Particulate Matter analysis, Quarantine, SARS-CoV-2, Air Pollutants analysis, Air Pollution analysis, Coronavirus Infections, Pandemics, Pneumonia, Viral
- Abstract
Nitrogen oxides (NOx), sulphur oxides (SOx) and ammonia (NH
3 ) are among the main contributors to the formation of secondary particulate matter (PM2.5 ), which represent a severe risk to human health. Even if important improvements have been achieved worldwide, traffic, industrial activities, and the energy sector are mostly responsible for NOx and SOx release; instead, the agricultural sector is mainly responsible for NH3 emissions. Due to the emergency of coronavirus disease, in Italy schools and universities have been locked down from late February 2020, followed in March by almost all production and industrial activities as well as road transport, except for the agricultural ones. This study aims to analyze NH3 , PM2.5 and NOx emissions in principal livestock provinces in the Lombardy region (Brescia, Cremona, Lodi, and Mantua) to evaluate if and how air emissions have changed during this quarantine period respect to 2016-2019. For each province, meteorological and air quality data were collected from the database of the Regional Agency for the Protection of the Environment, considering both data stations located in the city and the countryside. In the 2020 selected period, PM2.5 reduction was higher compared to the previous years, especially in February and March. Respect to February, PM2.5 released in March in the city stations reduced by 19%-32% in 2016-2019 and by 21%-41% in 2020. Similarly, NOx data of 2020 were lower than in the 2016-2019 period (reduction in March respect to February of 22-42% for 2016-2019 and of 43-62% for 2020); in particular, this can be observed in city stations, because of the current reduction in anthropogenic emissions related to traffic and industrial activities. A different trend with no reductions was observed for NH3 emissions, as agricultural activities have not stopped during the lockdown. Air quality is affected by many variables, for which making conclusions requires a holistic perspective. Therefore, all sectors must play a role to contribute to the reduction of harmful pollutants., (Copyright © 2020 Elsevier Inc. All rights reserved.)- Published
- 2020
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13. Fragile heroes. The psychological impact of the COVID-19 pandemic on health-care workers in Italy.
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Conti C, Fontanesi L, Lanzara R, Rosa I, and Porcelli P
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- Adult, Anxiety epidemiology, Depression epidemiology, Female, Health Personnel statistics & numerical data, Humans, Italy epidemiology, Male, Stress Disorders, Post-Traumatic epidemiology, Surveys and Questionnaires, Workload, COVID-19 epidemiology, Health Personnel psychology, Pandemics
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This survey-based study aimed to explore the mental health status and psychological care needs of 933 health-care workers in Italy during the COVID-19 outbreak. Sociodemographic data, exposure to COVID-19, perception of psychological care needs, depression, anxiety, somatization, and post-traumatic symptoms were concurrently assessed. The majority of the sample (71%) suffered from somatization and 55% of distress. Female care workers experienced higher levels of anxiety (d = 0.50) and somatization symptoms (d = 0.82) and stated they needed psychological care more than men (p < .001). Younger participants (aged <40 years-old) reported higher levels of somatization, depression, anxiety, and post-traumatic symptoms (effects size range from d = 0.22 to d = 0.31). Working in a high infected area (red-zones) and directly with COVID-19 patients (front-line) affected the psychological health of participants to a smaller degree. Health-care workers who lost one of their patients reported higher levels of depression (d = 0.22), anxiety (d = 0.19), post-traumatic symptoms (d = 0.30), and psychological care needs than those who did not have the same experience (p < .01). Health-care workers who perceived the need for psychological support scored above the clinical alarming level (cut-off scores) in all the psychological scales, ranging from 76% to 88%. Psychological distress (p < .01), anxiety (p < .05), depression (p < .05), and being women (p < .01) contribute to explain the need for psychological care and accounted for 32% of the variance in this sample. These findings point out the importance to consider the psychological impact of COVID-19 on Italian health-care workers and strongly suggest establishing psychological support services for providing adequate professional care., Competing Interests: The authors declare that the research was conducted in the absence of any competing interests (financial and non-financial) that could be construed as a potential conflict of interest.
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- 2020
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14. Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis.
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Alfredo C, Carolin S, Güliz A, Anne K, Antonio P, Alberto C, Stefano P, Antonino G, Harun B, Markus K, Franziska M, Phuong N, Franziska L, Peter V, Volker B, and David K
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- Adult, Aged, Aged, 80 and over, Algorithms, Brain Stem radiation effects, Dose Fractionation, Radiation, Germany, Humans, Italy, Magnetic Resonance Imaging, Middle Aged, Models, Statistical, Optic Chiasm radiation effects, Optic Nerve radiation effects, Radiometry, Reproducibility of Results, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome, Meningeal Neoplasms radiotherapy, Meningioma radiotherapy, Radiation Dose Hypofractionation, Radiosurgery methods, Radiotherapy methods, Skull Base Neoplasms radiotherapy
- Abstract
Background: This retrospective German and Italian multicenter analysis aimed to compare the role of normofractionated stereotactic radiotherapy (nFSRT) to CyberKnife-based hypofractionated stereotactic radiotherapy (CK-hFSRT) for skull base meningiomas., Methods: Overall, 341 patients across three centers were treated with either nFSRT or CK-hFSRT for skull base meningioma. Treatment planning was based on computed tomography (CT) and magnetic resonance imaging (MRI) following institutional guidelines. Most nFSRT patients received 33 × 1.8 Gy, and most CK-hFSRT patients received 5 × 5 Gy. The median follow-up time was 36 months (range: 1-232 months)., Results: In the CK-hFSRT group, the 1-, 3-, and 10-year local control (LC) rates were 99.4, 96.8, and 80.3%, respectively. In the nFSRT group, the 1-, 3-, and 10-year LC rates were 100, 99, and 79.1%, respectively. There were no significant differences in LC rates between the nFSRT and CK-hFSRT groups (p = 0.56, hazard ratio = 0.76, 95% confidence interval, 0.3-1.9). In the CK-hFSRT group, only one case (0.49%) of severe toxicity (CTCAE 4.0 ≥ 3) was observed. In the nFSRT group, three cases (2.1%) of grade III toxicity were observed., Conclusion: This analysis of pooled data from three centers showed excellent LC and low side effect rates for patients treated with CK-hFSRT or nFSRT. The efficacy, safety, and convenience of a shortened treatment period provide a compelling case for the use of CK-hFSRT in patients with moderate size skull base meningioma and provided that OAR constraints are met.
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- 2019
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15. The Injury-Psychological Readiness to return to sport (I-PRRS) scale and the Sport Confidence Inventory (SCI): A cross-cultural validation.
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Conti C, di Fronso S, Robazza C, and Bertollo M
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- Adolescent, Adult, Athletes, Cross-Sectional Studies, Factor Analysis, Statistical, Female, Humans, Italy, Language, Male, Psychometrics, Reproducibility of Results, Sports, Young Adult, Athletic Injuries psychology, Cross-Cultural Comparison, Return to Sport psychology, Surveys and Questionnaires
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Objectives: The purpose of this study was to cross-culturally validate in the Italian language the I-PRRS and the SCI., Design: Cross-sectional study., Setting: Injured Italian athletes., Participants: We recruited male (n = 73) and female (n = 27) athletes who returned to practice after having completed the rehabilitation., Main Outcome Measures: The measures comprised the I-PRRS, the SCI, and the Italian Mood Scale (ITAMS). Athletes completed the questionnaires within 1 day before their first official competition following injury. We investigated the construct validity, the internal consistency, and the concurrent validity of the I-PRRS and SCI with the ITAMS., Results: Confirmatory Factor Analysis supported the two-factor structure of the I-PRRS (Confidence in performance capability and Confidence in recovery) and the three-factor structure of the SCI (SC-Physical Skills and Training, SC-Cognitive Efficiency, and SC-Resilience). The reliability scores of both I-PRRS and SCI subscales indicated good internal consistency. Correlation between the I-PRRS and the SCI ranged in magnitude from weak to moderately high. A similar trend of correlations was found between the subscales of the I-PRRS and the ITAMS, as well as between the subscales of the SCI and the ITAMS., Conclusions: Study findings showed satisfactory psychometric properties of the Italian version of the I-PRRS and SCI., (Copyright © 2019 Elsevier Ltd. All rights reserved.)
- Published
- 2019
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16. The institution of a Multi-disciplinary Italian Breast Unit: Reflections of the first psychosocial research study results on distress and quality of life.
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Dionigi F, Milani R, Garcia-Etienne CA, Praticò V, Riboni G, Della Valle A, Ferrari A, Grasso D, Lasagna A, Pedrazzoli P, Klersy C, Politi P, Sgarella A, Manna S, and Conti C
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- Breast Neoplasms surgery, Female, Humans, Italy, Mastectomy, Middle Aged, Surveys and Questionnaires, Breast Neoplasms psychology, Quality of Life, Stress, Psychological
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Breast cancer affects patients both emotionally and physically. It is time to consider distress as the sixth vital sign in breast cancer patients in Europe. Between 2012 and 2015, our EUSOMA-certified multi-disciplinary group conducted a study on emotional distress and quality-of-life in breast cancer patients at diagnosis, and observed their trend over the first 8 months of treatment. One hundred and forty-nine patients concluded the program. The psycho-oncologist and the breast nurses gave out SF36, Hospital Anxiety and Depression Scale and Distress Thermometer. Our Italian data go along with the reported literature on distress and quality-of-life. Despite modern advances, experiencing breast cancer impacts on overall quality-of-life., (© 2019 Wiley Periodicals, Inc.)
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- 2019
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17. Laparoscopic colorectal surgery and Enhanced Recovery After Surgery (ERAS) program: Experience with 200 cases from a single Italian center.
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Pedrazzani C, Conti C, Mantovani G, Fernandes E, Turri G, Lazzarini E, Menestrina N, Ruzzenente A, and Guglielmi A
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- Adolescent, Adult, Aged, Aged, 80 and over, Colonoscopy methods, Colonoscopy rehabilitation, Female, Humans, Italy, Laparoscopy methods, Length of Stay, Male, Middle Aged, Postoperative Period, Prospective Studies, Recovery of Function, Treatment Outcome, Young Adult, Colon surgery, Laparoscopy rehabilitation, Postoperative Care methods, Program Evaluation, Rectum surgery
- Abstract
There is increasing evidence that minimally invasive techniques associated with Enhanced Recovery After Surgery (ERAS) protocols reduce surgery-related stress and promote faster recovery after major colorectal surgery. As a single tertiary referral center for colorectal surgery, our aim was to analyze the effects of our ERAS protocol on a heterogeneous population undergoing laparoscopic colorectal surgery.Prospectively collected data from 283 patients undergoing laparoscopic colorectal resection at the Division of General and Hepatobiliary Surgery, University of Verona Hospital Trust, between March 2014 and March 2018 were retrospectively analyzed. Patients' adherence to pre-, intra-, and postoperative ERAS protocol items together with surgical short-term outcomes such as morbidity, mortality, length of hospital stay, and readmission rate was considered.The study protocol was approved by the Ethics Committee of Azienda Ospedaliera Universitaria Integrata di Verona (CRINF-1034 CESC).During the study period, 200 patients met the inclusion criteria and were enrolled in the ERAS protocol. In this series, 34% of patients were aged 70 years or older. Rectal resections represented 26% of all cases, with stoma formation performed in 14.5% of patients. Despite such procedural heterogeneity, good short-term results were obtained: by postoperative day (POD) 2, 58.5% of patients had full return of bowel function, while 63.5% and 88% achieved regular soft diet intake and autonomous walking, respectively. Median (range) length of hospital stay was 5.5 days (2-40) with 71% of patients being discharged by POD 6. No postoperative mortality was recorded, and the rate of major complications was 3.5%. During the study period, 6 patients required redo surgery (3%) and 5 patients required rehospitalization within 30 days (2.5%).This study analyzing the results of the fast-track program in our first 200 cases confirms the feasibility and safety of ERAS protocol application within a heterogeneous population undergoing laparoscopic colonic and rectal resection for benign and malignant diseases.
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- 2018
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18. Promotion of hand hygiene: the experience of the orthopaedic hospital Gaetano Pini-CTO, Milan, Italy.
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Nobile M, Conti C, Bastianelli A, Piscitelli A, Calori GM, and Navone P
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- Disinfection, Guideline Adherence, Hand Disinfection methods, Health Personnel, Hospitals, Special, Humans, Infection Control methods, Italy, Orthopedics, Program Evaluation, Cross Infection prevention & control, Hand Hygiene standards
- Abstract
Background: Hand hygiene is the primary preventive measure against health care-associated infections in terms of cost-effectiveness. In 2005, the WHO proposed the "Global Patient Safety Challenge" campaign, with the aim of reducing the overall incidence of such infections, through multimodal programs and strategies, interactive training tools and standardised methods for monitoring compliance., Study Design: On the basis of project "Rimani", sponsored by the Health and Social Care Authority of Emilia-Romagna, the Istituto Ortopedico Gaetano Pini has implemented a project which seeks to increase healthcare staff's compliance with hand hygiene., Methods: A multidisciplinary working group was created to prepare the project documents. Starting from 5th April 2015, twenty operational units were asked to produce information and training material. On 5th May, during a conference, a committee selected the three best works. The material was distributed on a monthly basis to the various departments. In addition to the training, the specifically trained operators of the Medical Monitoring Department carried out direct hand washing tests, filling out appropriate checklists. Non-compliance relating to the technique recorded in 2014 and 2015 was compared and a statistical analysis was conducted using Student's t-test for paired data., Results: Three tests were carried out in 2014. Ninety-nine cases were monitored and 5 non-compliance cases were reported, concerning the execution of the procedural steps, the running time and closing the tap with one's hands at the end of the wash. In 2015 two tests, involving 30 operational units, were carried out. 60 observations were performed, and no non-conformities emerged concerning the technique. Statistical analysis showed a significant reduction of non-compliances between the 2014 and 2015 P = 0.000)., Conclusion: The results obtained agree with the main findings in literature. The comparison between the 2014 and 2015 tests shows a trend of improvement in the wash technique. This confirms the effectiveness of a multidisciplinary approach and recognises the active and participatory involvement suggested by the WHO.
- Published
- 2018
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19. Chemically and size-resolved particulate matter dry deposition on stone and surrogate surfaces inside and outside the low emission zone of Milan: application of a newly developed "Deposition Box".
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Ferrero L, Casati M, Nobili L, D'Angelo L, Rovelli G, Sangiorgi G, Rizzi C, Perrone MG, Sansonetti A, Conti C, Bolzacchini E, Bernardi E, and Vassura I
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- Italy, Particle Size, Particulate Matter chemistry, Seasons, Particulate Matter analysis
- Abstract
The collection of atmospheric particles on not-filtering substrates via dry deposition, and the subsequent study of the particle-induced material decay, is trivial due to the high number of variables simultaneously acting on the investigated surface. This work reports seasonally resolved data of chemical composition and size distribution of particulate matter deposed on stone and surrogate surfaces obtained using a new method, especially developed at this purpose. A "Deposition Box" was designed allowing the particulate matter dry deposition to occur selectively removing, at the same time, variables that can mask the effect of airborne particles on material decay. A pitched roof avoided rainfall and wind variability; a standardised gentle air exchange rate ensured a continuous "sampling" of ambient air leaving unchanged the sampled particle size distribution and, at the same time, leaving quite calm condition inside the box, allowing the deposition to occur. Thus, the "Deposition Box" represents an affordable tool that can be used complementary to traditional exposure systems. With this system, several exposure campaigns, involving investigated stone materials (ISMs) (Carrara Marble, Botticino limestone, Noto calcarenite and Granite) and surrogate (Quartz, PTFE, and Aluminium) substrates, have been performed in two different sites placed in Milan (Italy) inside and outside the low emission zone. Deposition rates (30-90 μg cm
-2 month-1 ) showed significant differences between sites and seasons, becoming less evident considering long-period exposures due to a positive feedback on the deposition induced by the deposited particles. Similarly, different stone substrates influenced the deposition rates too. The collected deposits have been observed with optical and scanning electron microscopes and analysed by ion chromatography. Ion deposition rates were similar in the two sites during winter, whereas it was greater outside the low emission zone during summer and considering the long-period exposure. The dimensional distribution of the collected deposits showed a significant presence of fine particles in agreement with deposition rate of the ionic fraction. The obtained results allowed to point out the role of the fine particles fraction and the importance of making seasonal studies.- Published
- 2018
- Full Text
- View/download PDF
20. From the risk analysis to the development of interventions and training for the prevention and control of healthcare associated infections. The experience of G. Pini Orthopedic Institute.
- Author
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Navone P, Conti C, Domeniconi G, and Nobile M
- Subjects
- Arthroplasty mortality, Critical Care statistics & numerical data, Cross Infection mortality, Humans, Incidence, Italy epidemiology, Length of Stay statistics & numerical data, Patient Admission statistics & numerical data, Population Surveillance, Practice Guidelines as Topic, Reoperation statistics & numerical data, Risk Assessment, Risk Factors, Survival Rate, Trauma Centers, Arthroplasty statistics & numerical data, Cross Infection epidemiology, Cross Infection prevention & control, European Union statistics & numerical data, Guideline Adherence, Orthopedics
- Abstract
Background: Health-care associated infections (HAIs) represents a phenomenon of central importance all over Europe. Every year 4,5 millions cases are detected in European Union, with 37.000 related deaths. Surgical-site infections (SSIs) are one of the most common HAIs, that are associated with an increased length of stay, re-operation rate, intensive care admissions rate, and higher mortality rate., Methods: G. Pini Orthopedics Institute implemented in the last two years a multimodal strategy for controlling and preventing HAIs, in particular for SSIs., Results: This paper describes the prevention's strategies adopted for prevention of HAIs, at G. Pini Orthopedic Institute., Conclusions: Our findings show that application of a multi modal promotion strategy was associated with an improvement in HAI prevention.
- Published
- 2015
- Full Text
- View/download PDF
21. Cost effectiveness of tibial nonunion treatment: A comparison between rhBMP-7 and autologous bone graft in two Italian centres.
- Author
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Giorgio Calori M, Capanna R, Colombo M, De Biase P, O'Sullivan C, Cartareggia V, and Conti C
- Subjects
- Clinical Protocols, Cost-Benefit Analysis, Female, Follow-Up Studies, Fracture Healing, Fractures, Ununited epidemiology, Fractures, Ununited therapy, Health Care Costs, Humans, Italy epidemiology, Male, Patient Readmission economics, Quality-Adjusted Life Years, Recombinant Proteins economics, Recombinant Proteins therapeutic use, Retrospective Studies, Tibial Fractures epidemiology, Tibial Fractures therapy, Treatment Outcome, Bone Morphogenetic Protein 2 economics, Bone Morphogenetic Protein 2 therapeutic use, Bone Transplantation economics, Fracture Fixation, Intramedullary economics, Fracture Fixation, Intramedullary methods, Fractures, Ununited economics, Length of Stay economics, Tibial Fractures economics
- Abstract
Current evidences show that recombinant human bone morphogenetic protein 7 (rhBMP-7, eptotermin alfa) can be considered an effective alternative to autologous bone graft (ABG) in the treatment of tibial nonunions. Few studies, so far, have analysed the costs of treating tibial nonunions with either rhBMP-7 or ABG and none of them has specifically considered the Italian situation. The aim of the present study was to capture, through observational retrospective methods, the direct medical costs associated with the treatment of tibial nonunions with rhBMP-7 or ABG in Italy and to compare the cost effectiveness of the two interventions. The secondary objective was to perform a cost-reimbursement analysis for hospitalisations associated with the two treatments. Data of 54 patients with indication for tibial nonunion were collected from existing data sources. Of these patients, 26 were treated with ABG and 28 with rhBMP-7. The study captured the direct medical costs for treating each tibial nonunion, considering both inpatient and outpatient care. The hospital reimbursement was calculated from discharge registries, based on diagnosis-related group (DRG) values. A subgroup of patients (n=30) was also interviewed to capture perceived health during the follow-up, and the quality-adjusted life years (QALYs) were subsequently computed. The two groups were similar for what concerns baseline characteristics. While the medical costs incurred during the hospitalisation associated with treatment were on average €3091.21 higher (P<0.001) in patients treated with rhBMP-7 (reflecting the product procurement costs), the costs incurred during the follow-up were on average €2344.45 higher (P=0.02) in patients treated with ABG. Considering all costs incurred from the treatment, there was a borderline statistical evidence (P=0.04) for a mean increase of €795.42, in the rhBMP-7 group. Furthermore, the study demonstrated that, without appropriate reimbursement, the hospital undergoes significant losses (P=0.003) when using rhBMP-7 instead of ABG. In contrast to these losses, in Italy, the average cost to achieve a successful outcome was €488.96 lower in patients treated with rhBMP-7 and, additionally, the cost per QALY gained was below the cost-utility threshold of $50,000., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
22. Micro HTA as a tool for clinical governance: the experience of the Breast Unit in "Santa Maria" Terni Hospital.
- Author
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Sanguinetti A, Lucchini R, Triola R, Avenia S, Bistoni G, Conti C, Santoprete S, and Avenia N
- Subjects
- Biomedical Technology methods, Clinical Governance, Female, Hospital Units, Hospitals, Humans, Italy, Biomedical Technology standards, Breast Neoplasms surgery, Mastectomy economics, Technology Assessment, Biomedical
- Abstract
The last decade has witnessed the affirmation of the paradigm Health Technology Assessment (HTA) as a tool for government innovation technology in health care. As is known, this is an approach of evaluation oriented policy making that, in addition to provide for the disclosure of its results, it is proposed to consider simultaneously the clinical, economic, organizational, ethical and social issues arising from the introduction or disposal of a health technology, understood in the broadest sense of the term. In order to reconstruct a realistic picture of its level of implementation we have reproduced a micro HTA which served to assess the Harmonic Focus® device usefulness in breast surgery.
- Published
- 2013
23. Specific language disorders and season of birth: underlying environmental factors or chance findings?
- Author
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Ghezzo A, Chiappedi M, Ballerini A, Seragni G, Zanette M, Conti C, Stefanini MC, Ferrari-Ginevra O, Spelta P, Angelini L, and Beghi E
- Subjects
- Adolescent, Age Factors, Birth Order psychology, Child, Child, Preschool, Confidence Intervals, Female, Humans, Italy, Male, Odds Ratio, Developmental Disabilities epidemiology, Environment, Language Disorders epidemiology, Parturition, Seasons
- Abstract
The medical records of 358 children and adolescents with specific language disorders (SLD; 122 girls and 236 boys) seen in rehabilitation centers from Northern and Central Italy were examined to compare season of birth in these cases to those of the Italian population. Exposure was calculated using univariate and multivariate odds ratios (ORs) and 95% confidence intervals (CIs). Compared to the Italian population, patients with SLD had a 1.67 (95% CI [1.35-2.07]) chance of birth in October-December. Independent predictors were younger age at inclusion and being firstborn. Different neurobiological hypotheses can be drawn to explain these findings.
- Published
- 2012
- Full Text
- View/download PDF
24. Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.
- Author
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Allanore Y, Saad M, Dieudé P, Avouac J, Distler JH, Amouyel P, Matucci-Cerinic M, Riemekasten G, Airo P, Melchers I, Hachulla E, Cusi D, Wichmann HE, Wipff J, Lambert JC, Hunzelmann N, Tiev K, Caramaschi P, Diot E, Kowal-Bielecka O, Valentini G, Mouthon L, Czirják L, Damjanov N, Salvi E, Conti C, Müller M, Müller-Ladner U, Riccieri V, Ruiz B, Cracowski JL, Letenneur L, Dupuy AM, Meyer O, Kahan A, Munnich A, Boileau C, and Martinez M
- Subjects
- Adult, Case-Control Studies, Europe, Female, France, Genetic Predisposition to Disease, Genome-Wide Association Study, Germany, HLA-DQ beta-Chains immunology, Humans, Italy, Linkage Disequilibrium, Major Histocompatibility Complex, Male, Polymorphism, Single Nucleotide, Proteins immunology, Scleroderma, Systemic immunology, rhoB GTP-Binding Protein immunology, DNA-Binding Proteins genetics, DNA-Binding Proteins immunology, HLA-DQ beta-Chains genetics, Proteins genetics, Scleroderma, Systemic genetics, rhoB GTP-Binding Protein genetics
- Abstract
Systemic sclerosis (SSc) is an orphan, complex, inflammatory disease affecting the immune system and connective tissue. SSc stands out as a severely incapacitating and life-threatening inflammatory rheumatic disease, with a largely unknown pathogenesis. We have designed a two-stage genome-wide association study of SSc using case-control samples from France, Italy, Germany, and Northern Europe. The initial genome-wide scan was conducted in a French post quality-control sample of 564 cases and 1,776 controls, using almost 500 K SNPs. Two SNPs from the MHC region, together with the 6 loci outside MHC having at least one SNP with a P<10(-5) were selected for follow-up analysis. These markers were genotyped in a post-QC replication sample of 1,682 SSc cases and 3,926 controls. The three top SNPs are in strong linkage disequilibrium and located on 6p21, in the HLA-DQB1 gene: rs9275224, P = 9.18×10(-8), OR = 0.69, 95% CI [0.60-0.79]; rs6457617, P = 1.14×10(-7) and rs9275245, P = 1.39×10(-7). Within the MHC region, the next most associated SNP (rs3130573, P = 1.86×10(-5), OR = 1.36 [1.18-1.56]) is located in the PSORS1C1 gene. Outside the MHC region, our GWAS analysis revealed 7 top SNPs (P<10(-5)) that spanned 6 independent genomic regions. Follow-up of the 17 top SNPs in an independent sample of 1,682 SSc and 3,926 controls showed associations at PSORS1C1 (overall P = 5.70×10(-10), OR:1.25), TNIP1 (P = 4.68×10(-9), OR:1.31), and RHOB loci (P = 3.17×10(-6), OR:1.21). Because of its biological relevance, and previous reports of genetic association at this locus with connective tissue disorders, we investigated TNIP1 expression. A markedly reduced expression of the TNIP1 gene and also its protein product were observed both in lesional skin tissue and in cultured dermal fibroblasts from SSc patients. Furthermore, TNIP1 showed in vitro inhibitory effects on inflammatory cytokine-induced collagen production. The genetic signal of association with TNIP1 variants, together with tissular and cellular investigations, suggests that this pathway has a critical role in regulating autoimmunity and SSc pathogenesis., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2011
- Full Text
- View/download PDF
25. Deliberate self-harm in substance-dependent patients and relationship with alexithymia and personality disorders: a case-control study.
- Author
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Verrocchio MC, Conti C, and Fulcheri M
- Subjects
- Adult, Case-Control Studies, Humans, Italy, Male, Substance-Related Disorders therapy, Surveys and Questionnaires, Young Adult, Affective Symptoms complications, Affective Symptoms psychology, Personality Disorders complications, Personality Disorders psychology, Self-Injurious Behavior complications, Self-Injurious Behavior psychology, Substance-Related Disorders complications, Substance-Related Disorders psychology
- Abstract
The aim of this study Is to evaluate differences in the prevalence of deliberate self-harm (DSH), alexithymia, and clinical personality patterns and syndromes between treatment-seeking substance-dependents and a comparison group, and to investigate the relationship of DSH with alexithymia, and personality disorders. One hundred and fifty-four subjects participated in the study (77 substance-dependent inpatients and 77 comparison group). DSM-IV diagnoses of substance dependence were made by the clinicians of the Addiction Services following assessment that included clinical observation. Participants were evaluated by the Deliberate Self Harm Inventory, Toronto Alexithymia Scale, and Millon Clinical Multiaxial Inventory. An Identifying Information Form was used to collect demographic information (e.g. age, educational history, marital status, and employment status). Only to the clinical sample information was added on: types of substance used, age at first substance use, age at regular substance use, and previous treatment attempts. Significant group differences were found for all measures (DSH, TAS-20, MCMI-III). Among substance-dependent patients there was a significant difference between groups with and without DSH in terms of previous treatment attempts, Hypomania and Borderline personality disorder. DSH were significantly correlated with difficulty in identifying feelings in all cases in both the comparison group and in the personality disorders group, and with difficulty describing feelings in the personality disorders group. Personality disorder and drug dependency were predictors for DSH. This study suggests that treatment of substance-dependents should involve screening for deliberate self-harm behavior, difficulty identifying and describing feelings, and personality disorders. Probably, when these problems are detected, specific psychological intervention should be integrated to usual treatment for substance-dependent patients.
- Published
- 2010
26. Patients with moderate head injury: a prospective multicenter study of 315 patients.
- Author
-
Compagnone C, d'Avella D, Servadei F, Angileri FF, Brambilla G, Conti C, Cristofori L, Delfini R, Denaro L, Ducati A, Gaini SM, Stefini R, Tomei G, Tagliaferri F, Trincia G, and Tomasello F
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Confidence Intervals, Craniocerebral Trauma diagnostic imaging, Craniocerebral Trauma epidemiology, Disability Evaluation, Disease Progression, Female, Forecasting, Glasgow Outcome Scale, Humans, Italy, Male, Middle Aged, Odds Ratio, Outcome Assessment, Health Care, Prospective Studies, Tomography, X-Ray Computed methods, Young Adult, Craniocerebral Trauma etiology, Craniocerebral Trauma surgery, Craniotomy methods, Neurosurgery methods
- Abstract
Objective: To analyze the risk factors of worst outcome associated with moderate head injury., Methods: Data on patients with moderate head injury were collected prospectively in 11 Italian neurosurgical units over a period of 18 months. Patients older than 18 years with blunt head injury and at least one Glasgow Coma Scale (GCS) score between 9 and 13 were enrolled. The outcome was determined at 6 months using the Glasgow Outcome Scale., Results: We analyzed 315 patients. Initial computed tomographic scans showed a diffuse injury type I or II in 63%, a mass lesion in 35%, and traumatic subarachnoid hemorrhage in 42% of the patients. The risk of progression toward a mass lesion was 23% when the admission computed tomographic scan showed diffuse injury type I or II. An emergency craniotomy was performed in 22% of the patients, delayed surgery was performed in 14%, and both were performed in 25%. A favorable outcome was obtained in 74% of the patients. When the GCS score was 9 or 10, the predictor of worst outcome was a motor GCS score of 4 or lower (odds ratio [OR], 8.08; 95% confidence interval [CI], 1.22-67.35; P = 0.008), but when the GCS score was 11 to 13, the factors associated with worst outcome were neuroworsening (OR, 3.43; 95% CI, 1.45-8.17; P = 0.002), seizures (OR, 7.94; 95% CI, 1.18-64.48; P = 0.02), and medical complications (OR, 4.24; 95% CI, 1.74-10.33; P = 0.0006)., Conclusion: There is a high percentage of surgery and worsening on computed tomographic scans in patients with moderate head injury. Neuroworsening, seizures, and medical complications as outcome predictors were more strongly associated with a GCS score of 11 to 13, whereas a low motor GCS score was more outcome-related in patients with GCS scores of 9 and 10.
- Published
- 2009
- Full Text
- View/download PDF
27. Does hospital work constitute a risk factor for Helicobacter pylori infection?
- Author
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Mastromarino P, Conti C, Donato K, Strappini PM, Cattaruzza MS, and Orsi GB
- Subjects
- Adult, Aged, Antigens, Bacterial isolation & purification, Enzyme-Linked Immunosorbent Assay, Female, Helicobacter pylori immunology, Humans, Italy epidemiology, Logistic Models, Male, Middle Aged, Prevalence, Risk Factors, Helicobacter Infections etiology, Helicobacter pylori isolation & purification, Occupational Exposure adverse effects, Personnel, Hospital
- Abstract
The aim of this study was to assess whether clinical work constitutes a risk factor for Helicobacter pylori infection among employees in hospitals. The prevalence of H. pylori infection was analysed in 249 individuals employed in a university teaching hospital according to three categories of hospital workers: (A) personnel from gastrointestinal endoscopy units (N=92); (B) personnel from other hospital units with direct patient contact (N=105); and (C) staff from laboratories and other units with no direct patient contact (N=52). Stool samples from each subject were examined with a validated enzyme-linked immunosorbent assay for the presence of H. pylori antigens. A questionnaire inquiring about sociodemographic and occupational characteristics was completed by each participant. The prevalence of H. pylori infection was 37.0% in group A, 35.2% in group B and 19.2% in group C (P<0.05). Among the different healthcare categories, nurses had a significant higher prevalence of H. pylori infection (P<0.01). No significant association was found between the length of employment or exposure to oral and faecal secretions, and H. pylori infection. Hospital work involving direct patient contact seems to constitute a major risk factor for H. pylori infection compared with hospital work not involving direct patient contact.
- Published
- 2005
- Full Text
- View/download PDF
28. Inorganic particles in bronchoalveolar lavage fluids from nonoccupationally exposed subjects.
- Author
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Falchi M, Biondo L, Conti C, Cipri A, de Marinis F, Gigli B, and Paoletti L
- Subjects
- Adult, Asbestos analysis, Carcinoma chemistry, Cohort Studies, Female, Humans, Italy, Life Style, Lung Neoplasms chemistry, Male, Microscopy, Electron, Middle Aged, Occupations, Smoking, Surveys and Questionnaires, Urban Health, Air Pollutants analysis, Bronchoalveolar Lavage Fluid chemistry, Minerals analysis
- Abstract
This study comprised 30 patients who had not been exposed occupationally to dusts, but for whom a diagnosis of suspected pulmonary carcinoma had been made. Bronchoalveolar lavage fluids from these patients were analyzed by transmission electron microscopy and by energy-dispersive x-ray microanalysis in an effort to study the mineral particulate present in the alveolar region. Particles of silica, silicates, oxides, sulphates, and metal alloys were detected in various percentages in each subject. The smoking habits of two groups of patients that were defined by their bronchoalveolar lavage particulate concentrations (i.e., lower or higher than the median of the distribution) differed significantly.
- Published
- 1996
- Full Text
- View/download PDF
29. [Clinico-statistical studies on 473 cases of epidemic parotitis].
- Author
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Ulivelli A, Gatta AM, Pecchioli A, Conti CA, and Calandi C
- Subjects
- Child, Child, Preschool, Female, Humans, Infant, Italy, Male, Mumps complications, Mumps diagnosis, Orchitis etiology, Pancreatitis etiology, Mumps epidemiology
- Published
- 1977
30. [Epidemiological and clinico-statistical findings on tuberculosis in children in the Firenze province. II. Data relating to morbidity and infectivity 1971-1980].
- Author
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Calandi C, Alfaioli G, Bianchera R, Montanari E, Ahmad Y, and Adami-Lami Conti C
- Subjects
- Adolescent, Age Factors, Child, Child, Preschool, Epidemiologic Methods, Female, Humans, Infant, Italy, Male, Sex Factors, Tuberculin Test, Tuberculosis, Pulmonary epidemiology, Tuberculosis, Pulmonary mortality
- Published
- 1982
31. [The incidence of the X-linked progressive muscular dystrophies in Tuscany from 1966 to 1974 (author's transl)].
- Author
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Pizzi A, Taiuti R, Calandi C, Adami-Lami Conti C, Ghezzi M, Fratiglioni L, and Marconi G
- Subjects
- Female, Humans, Italy, Muscular Dystrophies epidemiology, Mutation, X Chromosome, Muscular Dystrophies genetics
- Abstract
An investigation was carried out to establish the incidence of X-linked progressive muscular dystrophies in Tuscany from 1966 to 1974. 52 cases were identified, the incidence being 23,95 X 10(-5) with reference to live-born males. The frequency of new mutations calculated according to Haldane's method was 7,97 X 10(-6). These data practically correspond to those reported by other AA. in Italy and abroad. There was also a remarkable variability in the incidence among individual districts with values ranging from 7,60 X 10(-5) to 41,91 X 10(-5). It was noticed that the number of new cases tended to decrease in the last few years.
- Published
- 1981
32. [Epidemiologic and clinico-statistical data on infantile tuberculosis in the province of Florence with special reference to morbidity related to the 10-year period of 1962-1971].
- Author
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Calandi C, Gatta AM, Conti CA, Pecchioli A, and Pieroni P
- Subjects
- Adolescent, Adult, Child, Child, Preschool, Disease Outbreaks, Europe, Humans, Infant, Infant, Newborn, Italy, Retrospective Studies, Tuberculosis, Pulmonary epidemiology, Tuberculosis, Pulmonary mortality, Tuberculosis epidemiology
- Published
- 1973
33. [Schoenlein-Henoch disease in the case records of the Clinica Pediatrica di Florence].
- Author
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Adami-Lami Conti C, Martinucci M, Gatta AM, Nistri R, and Calandi C
- Subjects
- Age Factors, Child, Child, Preschool, Female, Humans, IgA Vasculitis complications, Italy, Kidney Diseases etiology, Male, Seasons, IgA Vasculitis epidemiology
- Published
- 1977
34. Goffredo Gensini, MD (1928-1986).
- Author
-
Conti CR
- Subjects
- Angiography history, Cardiology history, Catheterization history, Catheterization instrumentation, History, 20th Century, Italy, United States
- Published
- 1987
- Full Text
- View/download PDF
35. [Morbidity and mortality in the offspring of 300 consanguineous couples in Florence].
- Author
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Bigozzi U, Conti C, Guazzelli R, Montali E, and Salti F
- Subjects
- Adult, Congenital Abnormalities genetics, Female, Genes, Lethal, Genes, Recessive, Humans, Italy, Male, Middle Aged, Pregnancy, Abortion, Spontaneous, Consanguinity, Fetal Death, Genetic Diseases, Inborn genetics, Infant Mortality, Intellectual Disability genetics
- Published
- 1970
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