1. Invasive group a streptococcal infections, Israel.
- Author
-
Moses AE, Goldberg S, Korenman Z, Ravins M, Hanski E, and Shapiro M
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cohort Studies, Humans, Incidence, Israel epidemiology, Jews, Middle Aged, Prospective Studies, Serotyping, Streptococcal Infections microbiology, Streptococcal Infections mortality, Streptococcus classification, Streptococcus genetics, Streptococcus isolation & purification, Streptococcus pathogenicity, Streptococcal Infections epidemiology
- Abstract
We conducted a prospective, nationwide, population-based study of invasive group A streptococcal infections in Israel. We identified 409 patients (median age 27 years; range <1-92), for an annual incidence of 3.7/100,000 (11/100,000 in Jerusalem). The mortality rate was 5%. Bacteremia occurred in 125 cases (31%). The most common illnesses were soft-tissue infection (63%) and primary bacteremia (14%). Thirty percent of patients had no identifiable risk factors for infection. Eighty-seven percent of pharyngeal carriers had the same serotype as the index patient. M types included M3 (25%), M28 (10%), and M-nontypable (33%). A marked paucity of M1 serotype (1.2%) was detected. The results highlighted concentrated pockets of invasive disease in the Jewish orthodox community (annual incidence 16/100,000).
- Published
- 2002
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