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Indonesia resides on most earthquake region with more than 100 active volcanoes, and high number of seismic activities per year. In order to reduce the casualty, some method to predict earthquake have been developed to estimate the seismic movement. However, most prediction use only short term of historical data to predict the incoming earthquake, which has limitation on model performance. This work uses medium to long term earthquake historical data that were collected from 2 local government bodies and 8 legitimate international sources. We make an estimation of a mediumto- long term prediction via machine learning algorithms, which are multinomial logistic regression, support vector machine and Na¨ıve Bayes, and compares their performance. This work shows that the support vector machine outperforms other method. We compare the root mean square error computation results that lead us into how concentrated data is around the line of best fit, where the multinomial logistic regression is 0.777, Na¨ıve Bayes is 0.922 and support vector machine is 0.751. In predicting future earthquake, support vector machine outperforms other two methods that produce significant distance and magnitude to current earthquake report. [ABSTRACT FROM AUTHOR]

Background: The etiology of unexplained infertility has not been fully understood. This study aimed to determine the effect of antisperm antibody (ASA) from infertile women on viability, motility, plasma membrane integrity, and status of tyrosine phosphorylation in the human spermatozoa. Methods: An experimental in vitro study was conducted at the Department of Biology, Faculty of Medicine, Universitas Indonesia from February to November 2014. Spermatozoa from normal fertile donors was incubated with serum containing ASA from infertile women at several dilutions (1/1000, 1/100, 1/10, and without dilution) for 1 and 2 hours. The plasma membrane integrity was assessed with hypoosmotic swelling (HOS) test, whereas the status of tyrosine phosphorylation was analyzed using Western immunoblotting and immunocytochemistry. Results: After 1 hour incubation time, ASA caused a decrease in sperm viability, motility, plasma membrane integrity, and inhibit sperm tyrosine phosphorylation. ASA caused a decrease in viability, motility, sperm plasma membrane integrity, and tyrosine phosphorylation of sperm after 1 hour incubation time. Conclusion: ASA from infertile women reduced the sperm viability, motility, plasma membrane integrity, and capacitation in dose and time dependent manner. [ABSTRACT FROM AUTHOR]