1. Genotyping of Porcine teschovirus from nervous tissue of pigs with and without polioencephalomyelitis in Indiana.
- Author
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Bangari DS, Pogranichniy RM, Gillespie T, and Stevenson GW
- Subjects
- Animals, Encephalomyelitis epidemiology, Encephalomyelitis virology, Genotype, Indiana epidemiology, Phylogeny, Picornaviridae Infections epidemiology, Picornaviridae Infections virology, Swine, Swine Diseases epidemiology, Brain virology, Encephalomyelitis veterinary, Picornaviridae Infections veterinary, Spinal Cord virology, Swine Diseases virology, Teschovirus genetics
- Abstract
Porcine teschovirus (PTV) was isolated in cell culture and/or demonstrated by polymerase chain reaction in samples of brain and/or spinal cord in pigs in Indiana during the 2002-2007 period. Testing was initiated on pigs originating from populations exhibiting nervous clinical disease and/or pigs with microscopic lesions in central nervous tissues, indicating viral encephalitis and/or myelitis. Virus was demonstrated in pigs with and without lesions as well as with and without nervous clinical disease. Nucleotide sequence analysis of the 5'-nontranslated region of the viral genome revealed that these isolates had low-level genetic heterogeneity but were homologous to porcine PTV serotype 1 (PTV-1). These findings indicate that low-to-moderate virulence strains of PTV with some homology to PTV-1 are endemic in many swineherds of Indiana and are associated with subclinical and clinical nervous disease in weaned pigs.
- Published
- 2010
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