1. Evaluation of Antimicrobial and Antioxidant Properties of Pithecolobine Isolated from Albizia saman.
- Author
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Thippeswamy, Sreerangegowda, Mohana, Devihalli Chikkaiah, Abhishek, Rayasandra Umesh, and Manjunath, Kiragandur
- Subjects
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ANTI-infective agents , *ANTIOXIDANTS , *DRUG resistance in microorganisms , *DRUG side effects , *INFRARED spectroscopy , *MASS spectrometry , *MEDICINAL plants , *RESEARCH funding , *SPECTROPHOTOMETRY , *STATISTICS , *THIN layer chromatography , *DATA analysis , *DATA analysis software , *DESCRIPTIVE statistics , *IN vitro studies - Abstract
Pithecolobine isolated from alkaloid extract ofAlbizia samanshowed antimicrobial activity against seven human pathogenic bacteria and two yeasts with minimum inhibitory concentrations (MIC) values of 1.9–125 μg mL−1. In addition, it also exhibited antioxidant activity with IC50value at 250μg mL−1. Pithecolobine may be useful as a natural bioactive molecule for developing potent antimicrobial and antioxidant agents. [ABSTRACT FROM PUBLISHER]
- Published
- 2015
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