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Describes a curriculum development pilot study in a rural village in India, designed to develop and test application of an ecological inventory approach to curriculum development integrating academic and functional skill training. Describes an Integrated Core Curriculum Structure as a guide for designing curricula based on ecological inventories. (Contains 21 references.) (VWC)

Anti-tumor necrosis factor-alpha (TNF-α) immunotherapy has revolutionized the treatment of inflammatory diseases, such as psoriasis and psoriatic arthritis. However, a major concern is that patients receiving this therapy have an increased risk of infection, particularly of reactivation of latent tuberculosis (TB). There were an estimated 10.4 million new cases of tuberculosis in 2016, worldwide, and India has one of the largest TB case burden with an estimated incidence of 2.79 million cases of TB in the same year. Anti-TNF agents like etanercept and infliximab are available in India approved for psoriasis and psoriatic arthritis. But long-term use of these agents possesses a risk of reactivation of latent TB. In this review article, we assessed the risk of TB with anti-TNF therapy especially in patients with psoriasis and psoriatic arthritis in India. At the end of the article, we have also suggested a recommendation for screening of latent tuberculosis and its management, before starting anti-TNF-α therapy. [ABSTRACT FROM AUTHOR]

Chilika Lake, Asia's largest brackish water lagoon, is located in the state of Odisha on the east coast of India. It was designated as a Ramsar site in 1981, being the first Indian wetland of international importance under the Ramsar convention. Siltation of the lake is become a major concern, because it is leading to various geomorphic changes that are affecting the shape and size of the lagoon, which receives a major silt load through the Daya and Bhargovi rivers (both being branches of the Mahanadi river) via the Kathajodi and Kuakhai rivers. The Naraj barrage was constructed at the mouth of the Kathajodi river to regulate its inflow, and also its silt load, into the lagoon. Two observatories are established in the Daya and Bhargovi rivers to determine the quantity of silt entering Chilika Lake through the rivers, with the bed load and suspended (total solids) being measured. Various effects of siltation in the lagoon because of the barrage are analysed in this study, to include the pre- and postconstruction situation. By considering different flood situations in the Mahanadi river, various alternate strategies for operation of the Naraj barrage were studied, with the goal of minimizing the siltation in Chilika Lake. These alternate operation strategies, and their potential effects on the inflow into the lagoon, are analysed and discussed in this report. [ABSTRACT FROM AUTHOR]

The article describes the case of a 10-year-old boy who showed progressive painless dimness of vision which was preceded by difficulty in reading and handwriting, difficulty in using the left side of the body, and continual falling over, and was later diagnosed with neurofibromatosis type 1 (NF1).