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Background: Many cases of multisystem inflammatory syndrome in children (MIS-C) are reported in post-COVID-19 cases. It is a serious complication of COVID-19, with a high mortality rate in low-income countries compared to high-income countries. This study was conducted to find out predictors of mortality in MIS-C. Subjects and Methods: In this prospective observational study, 81 children with MIS-C were enrolled. Detailed clinical features, laboratory parameters, treatment, and outcome of cases were recorded. After the determination of individual factors associated with mortality by univariate analysis, a binary logistic regression model of significant factors associated with mortality was developed. Results: Fever, breathlessness, conjunctivitis, and pain abdomen were major presenting complaints at admission. Fifty-seven (70.3%) were presented with shock, of which 31 (54.4%) had normotensive shock and 26 (45.6%) had hypotensive shock. There were 8 (9.8%) deaths in the study group. Association of pneumonia, acute respiratory distress syndrome, and acute kidney injury were significantly high among nonsurvivors. Levels of lactate dehydrogenase (LDH), interleukin-6, and prothrombin time (international normalized ratio) were significantly higher in nonsurvivors than survivors. On binary logistic regression, raised LDH and the use of a mechanical ventilator were found to be independent predictors of death (P < 0.05). Conclusions: Shock was the predominant manifestation in children with MIS-C. Raised LDH and the use of mechanical ventilators were found to be independent predictors of death in cases of MIS-C. [ABSTRACT FROM AUTHOR]

Chia (Salvia hispanica L.), of the mint family Lamiaceae, is one of the most highly nutritious crops in the world. It has a high economic value in both national and international markets. The present study was carried out with the prime objective of assessing Chia's morphological, biochemical, and nutritional characterization. An average yield of Chia (784 kg/ha) from the field experiment was observed. The biochemical studies showed the presence of higher amounts of carbohydrates, phenols, flavanols and antioxidants. The seed protein content of Chia was evaluated, and it was found to be 183 mg/g, which was greater than other major crops like wheat, rice and maize. The Carbohydrate content (371 mg/g) was also high in Chia seeds. High amounts of phenols (1.29 mgGAE/g) and flavonoids (0.48 mg/g) in Chia seeds were also observed. The mineral content estimated by ICP-OES showed the presence of micronutrients like Fe (11.7 mg/100g), Mg (335 mg/100g), Mn (5.97 mg/100g), Zn (12.01 mg/100g), Cu (1.94 mg/100g), Ca (397.78 mg/100g), Na (42.15 mg/100g) and K (605.83 mg/100g). The FTIR analysis showed the presence of the functional groups, and high peak banding was found related to protein, pectin (polysaccharides), PUFA (fatty acids), lipids etc. The HPTLC analysis indicated the presence of Gallic acid. Thus the present study unveils that the seeds of the Chia crop are a rich source of different essential elements. Hence this pseudo-cereal Chia can be used to provide good food supplements. As this is a newly introduced crop in India, there is very less study on the crop. To utilize the benefits of this crop, further research in various aspects to increase the environment adaptability and yield should be done. [ABSTRACT FROM AUTHOR]