1. Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature.
- Author
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Leroy J, Cornu M, Deleplancque AS, Bart A, Loridant S, Fréalle E, Dutoit E, Gaillot O, van Gool T, Puisieux F, Labalette P, and Sendid B
- Subjects
- Cornea drug effects, Cornea microbiology, Cornea pathology, Cornea surgery, Debridement methods, Eye Infections, Fungal drug therapy, Eye Infections, Fungal microbiology, Eye Infections, Fungal surgery, France, Humans, India, Keratoconjunctivitis drug therapy, Keratoconjunctivitis microbiology, Keratoconjunctivitis surgery, Male, Microsporidiosis drug therapy, Microsporidiosis microbiology, Microsporidiosis surgery, Middle Aged, Travel, Vittaforma drug effects, Vittaforma growth & development, Vittaforma pathogenicity, Antifungal Agents therapeutic use, Eye Infections, Fungal diagnosis, Fluoroquinolones therapeutic use, Keratoconjunctivitis diagnosis, Microsporidiosis diagnosis
- Abstract
Microsporidia are protists close to the kingdom of fungi that may cause eye infections. Most cases are reported in Asia and affect both immunocompromised and immunocompetent patients. Here, we report a rare case of microsporidial keratoconjunctivitis in an immunocompetent French patient 3 weeks after returning from India. In our patient, Weber trichrome staining of conjunctival scrapings revealed rounded elements approximately 1-3 μm in size. Conventional polymerase chain reaction analysis by ribosomal RNA subunit sequencing showed 100% identity with Vittaforma corneae . Treatment by corneal debridement combined with fluoroquinolone eye drops allowed complete resolution of the lesions. Although rare, ocular microsporidiosis should be investigated in a patient who is native to Asia or has returned from an endemic area and presents with keratoconjunctivitis of undetermined etiology.
- Published
- 2018
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