1. Clinical Characteristics of Primary Vitreoretinal Lymphoma in an Indian Population.
- Author
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Mahajan, Sarakshi, Nijhawan, Raje, Rajwanshi, Aravind, Karkhur, Samendra, Mulkutar, Samyak, Dogra, Mohit, Lal, Vivek, Gupta, Vishali, and Gupta, Amod
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UVEITIS , *EYE inflammation , *METHOTREXATE , *VASCULITIS , *IRIDOCYCLITIS , *EYE diseases , *OPHTHALMOLOGY , *OPTIC nerve diseases , *IMMUNOSUPPRESSIVE agents , *ANGIOGRAPHY , *OPHTHALMIC surgery , *OCULAR tumors , *INJECTIONS , *VISUAL acuity , *VITREOUS body , *RETINA , *RETROSPECTIVE studies , *DIAGNOSIS , *TUMORS - Abstract
Purpose: Primary vitreoretinal lymphomas (PVRL) pose a major diagnostic challenge, especially in the countries with a high prevalence of infectious variety of uveitis. The present study aims to report the clinical characteristics and diagnostic difficulties in patients with PVRL in an Indian Population.Methods: Retrospective chart reviews of 12 patients with a diagnosis of PVRL.Results: The study included 6 men and 6 women, with a mean age of 55.66 ± 8.76 years. All had bilateral disease. The clinical signs included anterior uveitis (12 eyes; 50.0%); vitritis (18 eyes; 75%); vitreous clumps (16 eyes; 66.6%); subretinal deposits (11 eyes; 45.8%); retinal vasculitis (6 eyes; 25%); and optic disc swelling (2 eyes; 8.3%). The most commonly mistaken diagnosis was intraocular tuberculosis. The intraocular lesions responded to multiple intravitreal methotrexate injections.Conclusions: PVRL in India was likely to be mistaken for an infectious variety of uveitis. A high index of suspicion and thorough clinical examination is necessary to make the diagnosis. [ABSTRACT FROM AUTHOR]- Published
- 2017
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