1. Effect of a collaborative care model on anxiety symptoms among patients with depression and diabetes in India: The INDEPENDENT randomized clinical trial.
- Author
-
Kemp, Christopher G., Johnson, Leslie C.M., Sagar, Rajesh, Poongothai, Subramani, Tandon, Nikhil, Anjana, Ranjit Mohan, Aravind, Sosale, Sridhar, Gumpeny R., Patel, Shivani A., Emmert-Fees, Karl, Rao, Deepa, Narayan, K.M.V., Mohan, Viswanathan, Ali, Mohammed K., and Chwastiak, Lydia A.
- Subjects
- *
MEDICAL care , *PATIENTS , *TREATMENT effectiveness , *TYPE 2 diabetes , *RANDOMIZED controlled trials , *INTERPROFESSIONAL relations , *MENTAL depression , *PSYCHOSOCIAL factors , *DESCRIPTIVE statistics , *ANXIETY , *PEOPLE with diabetes - Abstract
We assessed the impact of a collaborative care intervention on anxiety symptoms among participants in India with comorbid depression, poorly controlled diabetes, and moderate to severe anxiety symptoms. We analyzed data from a randomized controlled trial conducted at four diabetes clinics in India. Participants received either collaborative care or usual care. We included only participants who scored ⩾10 on the Generalized Anxiety Disorder-7 (GAD-7) at baseline. We estimated the effect of the intervention on clinically significant reduction in anxiety symptoms; we considered several potential baseline moderators and mediation by anti-depressant use. One hundred and seventy-two participants scored 10 or above on the GAD-7 at baseline. Collaborative care participants were more likely than control participants to achieve a clinically significant reduction in anxiety symptoms at 6 and 12 months (65.7% vs. 41.4% at 12 months, p = 0.002); these differences were not sustained at 18 or 24 months. There was little evidence of moderation by participant characteristics at baseline, and effects were not mediated by anti-depressant use. Collaborative care for the treatment of depression and type 2 diabetes can lead to clinically significant reductions in anxiety symptoms among patients with anxiety. Effects were notable during the active intervention period but not over the year post-intervention. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF