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Purpose: To report the early postoperative causes of intraocular pressure (IOP) spikes after complete circumferential gonioscopy-assisted transluminal trabeculotomy (GATT) using anterior segment optical coherence tomography (ASOCT). Methods: This was retrospective interventional case series of patients who underwent circumferential GATT by a single surgeon (APR) from 2021 to 2022 at a tertiary eye care in East India and who developed IOP spikes at 1 day-2 weeks (immediate) or early (> 2 weeks– 2 months) after GATT. The intraocular pressure (IOP), glaucoma medications, and angle evaluation by ASOCT at 1 week, and 1 month were compared between the two groups. Results: Thirty-two eyes of 32 consecutive patients, aged 40± 20.1 years (20 exfoliation glaucoma, 9 juvenile open-angle, and 3 developmental glaucoma), that developed IOP spikes between immediate (n=20) or early (n=12) IOP spikes after GATT, were included. Immediate postoperative spikes were seen in 20 eyes due to retained viscoelastic (n=8), hyphema (n=8) in uncontrolled hypertension, and peripheral anterior synechiae (PAS) (n=6) of which only one eye required medication at 2 months. Causes of immediate IOP spikes on ASOCT included an inverted/reattached trabecular shelf, iris strands in eyes with abnormal iris in developmental glaucoma, and PAS in 1– 2 quadrants. Causes of early IOP spikes included PAS > 3 quadrants (n=8), and hyperreflective fibrotic tissue over TM (n=4) with 50% requiring medications at 2 months. The ASOCT features predicting the need for medications were PAS > 3 quadrants (OR=8.4[2.2– 14.3], p=0.03) and fibrotic TM closure (OR=5.4, [3.6– 10.2], p=0.003). One eye with macrohyphema 3 days after surgery owing to uncontrolled hypertension (owing to the stoppage of medicines), required additional incisional trabeculectomy within 1 month of surgery. Conclusion: Immediate IOP spikes are mostly self-resolving as opposed to early IOP spikes > 2 weeks that require medications after GATT. Gonioscopic PAS > 3 quadrants, and fibrotic TM closure were the main identifiable ASOCT causes predicting the need for medications after GATT. [ABSTRACT FROM AUTHOR]

"Trade has the benefits which no country can deny. It is the lifeline of the people living across different boundaries. In the absence of trade, the happiness of the world would be at least reduced to half if not vanish". The role played by foreign trade in the development of the economies of different nations can never be overstated. Foreign trade has been rightly called upon as the engine of economic growth by many prominent economists of international repute. In the absence of international trade, nations would find it not only difficult to utilise their economic resources to the optimum level, but also will not be able to fulfil all the demands of consumption of the people in their economies. Present paper endeavours to present the utility of international trade in the development of any economy and volume of foreign trade in pre-reforms and post-reforms periods. [ABSTRACT FROM AUTHOR]

In the 1980s the US government sought to encourage India to liberalize its trade regime in services and foreign investment. US officials sought to achieve their objective by naming India to the 1988 Trade Act's 'Super 301' list of target countries for mandatory market-opening negotiations under threat of retaliation while at the same time also pursuing Indian trade liberalization multilaterally under the General Agreement on Tariffs and Trade (GATT) Uruguay Round negotiations. The two policies were uncoordinated and incompatible, and ultimately the Super 301 cases against India were terminated when US officials realized that they risked damaging prospects of success under the Uruguay Round talks. As a case study the US-India case exposes weaknesses in the ability of state actor-based theories of hegemonic stability as well as domestic politics and institutions-based explanations alone to yield a full account of interest formation and policy formulation. An integrative theoretical approach taking account of the role of epistemic communities is required to provide the fullest explanation both of individual decision making and institutional and structural factors. [ABSTRACT FROM AUTHOR]