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Introduction: Cardiovascular disorders have long been considered as one of the leading causes of mortality in India, which when presented with concurrent Coronavirus Disease (COVID-19) infection becomes even more fatal. Evidence suggests that COVID-19 affects the cardiovascular system by causing exuberant cytokinaemia, which results in endothelial inflammation and microvascular thrombosis, leading to multiorgan failure. Aim: To analyse the outcome of the asymptomatic COVID-19 patients presenting with cardiac angina during the second wave of COVID-19 in India. Materials and Methods: This is a retrospective data analysis of asymptomatic COVID-19 patients hospitalised with angina was conducted between April 2021 to June 2021 at Bardhhaman Medical College and Hospital located at Bardhdhaman district of West Bengal, India. A total of 1235 patients underwent all regular biochemical, haematological and cardiac investigations after undergoing test for COVID-19 test. Data was retrospectively collected. The outcome of these patients was analysed. Estimation of mean, standard deviation, percentage, p-value (from Pearson's correlation) was performed to establish the aim of the study. Results: Seventy six out of 1235 patients tested positive for asymptomatic COVID-19. The mean age of this study population was 55.075±10.95 years, of which were 55 male and 21 female. Hypertension was the most prevalent co-morbidity followed by diabetes, 73 (96%) presented with chest pain. A total of 47(62%) of these 76 patients had ST Elevated Myocardial Infarction (STEMI). Eleven (14.4%) underwent Percutaneous Coronary Intervention (PCI) whereas 36 (47.3%) underwent fibrinolytic therapy with tenecteplase, followed by secondary PCI in 27 (75%) of them. Rest 29 (38%) were medically managed for unstable angina. Mortality rate was as low as 6.5%. Age and comorbidity were the contributing factors for STEMI among asymptomatic COVID-19 patients. Conclusion: The results indicate that age and comorbidity are the factors, which lead to death or increases the life risk among patients with asymptomatic COVID-19. In this study, we have established that for the current patient population STEMI and age are negatively corelated. Medical management with thrombolytic agent became a lot more accepted in this scenario. PCI still remains the gold standard to treat myocardial infarction. It is recommended that there should be an ICMR guided protocol for the management of such cases with the concurrent COVID-19. [ABSTRACT FROM AUTHOR]

Aim: We assessed whether women were more affected by the dramatic drop in hospital admissions for ACS during the Covid-19 pandemic. Methods: This evaluation is an Institutional Review Board (IRB) exempt retrospective, observational study performed inBurdwan Medical College, Burdwan, West Bengal, India. We performed chart review of 1000 patients who presented to Burdwan Medical College, Burdwan, West Bengal, India Catheterization lab for elective and emergency catheterization for non ACS and ACS [NSTEMI, Unstable angina (UA), STEMI] during a 4-week period from February 26 to March 10 and from March 25 to April 8 and compared with the equivalent weeks in the last year. Results: Out of 1000, only 450 patients underwent cardiac catheterization for acute coronary syndrome. Remaining patients underwent cardiac catheterization for causes other than acute coronary syndrome, such as atrial septal defect closure, pulmonary arterial hypertension to assess hemodynamics in the heart chambers, cardiac myxoma, treatment of valvular heart disease (e.g., transcatheter mitral valve repair), assessment of the congenital heart diseases like cor triatriatum. Conclusion: In conclusion, the pandemic period reduced the gap between men and women in ACS: the extraordinary reduction in admission rates observed during the Covid-19 pandemic seems to have strongly affected women as men, with similar rates of reduction of hospitalized STEMI and NSTEMI and a trend toward greater reduction in UA admission among women. [ABSTRACT FROM AUTHOR]

Aim: The aim of the present study was to evaluate ST elevation myocardial infarction of inferior wall and right ventricle in rheumatic mitral stenosis due to thrombus at right coronary sinus. Methods: The present study was conducted in the Department of cardiology, Burdwan medical college and hospital, West Bengal, India. Acute MI was diagnosed by the presence of at least 2 of the following criteria: electrocardiographic changes, significant rises in myocardial bound creatine kinase fraction, and typical chest pain. Inferior wall MI was diagnosed by electrocardiography, echocardiography and coronary angiography. In patients with non-ST elevation MI, echocardiography and coronary angiographic findings were used for determination of the diagnosis of inferior wall MI. There was total 100 patients included in the present study. Results: Echocardiography was performed within 1.7±1.4 days (range 0-5) after acute MI. There were no differences in age, sex and other frequencies of underlying diseases among the 3 groups. There were no differences in the modality of intervention, severity of coronary artery disease. Fifty-five (73.34%) patients had the culprit lesion in the right coronary artery and 20 (26.6%) patients had the culprit lesion in the left circumflex artery. Patients whose culprit lesion in the left circumflex artery had an increased frequency of more severe MR than those with the culprit lesion in the right coronary artery, but this difference did not reach statistical significance (P=0.420). Conclusion: In the acute phase of inferior wall MI, MR was associated with LV systolic dysfunction with tethering. Therefore, it can be suggested that reduced closing force as a consequence of LV systolic dysfunction in the presence of leaflet tethering would play a more pivotal role in the development of MR in the acute phase of inferior MI, whereas increased tethering forces through a combination of annular dilation and geometric remodeling of the LV would be more important contributor in the chronic phase. [ABSTRACT FROM AUTHOR]