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Background: In poor nations like India, enteric fever is a severe health issue. For the purpose of diagnosing enteric fever, the Widal test is frequently utilized. In the Western Region of India, this study attempted to measure the baseline antibody titers for Salmonella typhi and paratyphi A, B in healthy persons. Methods: A total of 150 blood samples from healthy persons were taken, and the pattern of antibody titer was determined using the conventional quantitative tube method. Results: Among 150 blood samples, 103 had shown significant antibody titers (≥ 1:20). The significant proportion (10.7%) of the individuals had anti-O titer ≥ 1:80. Similarly, 86 had anti-H titers of ≥ 1:20 to S. enteric serotype typhi, 23 had a titer of ≥1:80 and 4 had a titer of ≥1:160 respectively. We found 10% and 1.3% for paratyphi A and B, anti-H titers of ≥ 1:20respectively. Conclusion: The study's findings suggest that the Western Development Region of India should modify the threshold values for antibody titers against S. typhi to > 1:80 for both anti-O and anti-H titers. [ABSTRACT FROM AUTHOR]