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Objectives: The main goal of this study is to publish findings on the lifestyle factors of pregnant women in Hungary and their impact on early childhood health status by examining changes over time and regional/geographical disparities. Methods: The source of the data is the raw indicators reported by health visitors as per mandatory annual report data for the period of 1997–2019. To examine the association, we used indicators of pregnant women's states as explanatory variables (for example, pregnant women in very late care, prenatal smoking habits, and pregnant women without care), and the outcome indicators were prematurity, intrauterine malnutrition, and newborn babies with developmental disorders. A univariate Poisson regression was used to examine the correlations. Results: Our results show a decreasing trend in the proportion of pregnant women who smoke and of pregnant women who apply late for care (after 28 weeks of pregnancy), with an increasing indicator of regional differences. The research results of the prenatal and perinatal indicators show that the counties Borsod-Abaúj-Zemplén and Szabolcs-Szatmár-Bereg are the most critical areas in terms of health status in Hungary. The number of pregnancies attended very late (after 28 weeks) and the number of women who gave birth without health visitor care are associated with the number of preterm births (R2 = 0.7313; p < 0.001; R2 = 0.5519; p < 0.001) and intrauterine growth restrictions (R2 = 0.3306; p < 0.001; R2 = 0.2632; p < 0.001). Conclusion: Interventions to improve early childhood health in some counties of Hungary are urgently needed to reduce regional disparities. Such counties include Borsod-Abaúj-Zemplén, Szabolcs-Szatmár-Bereg, Heves, Somogy, Bács-Kiskun, and Nógrád. Health education for pregnant women and activities to strengthen the compliance of pregnant women are key to improving early childhood health outcomes. [ABSTRACT FROM AUTHOR]

This empirical research on children's poverty and the accompanying risk behavior was conducted in the Baktalórántháza micro-region, in one of the most disadvantaged micro-regions of Hungary. The study, completed in 2023, was conducted utilizing three methods, a questionnaire for families, interviews, and focus group interviews with social professionals working in the settlements. The region is one of the ten micro-regions with the highest poverty rate in the country. The majority of the population only has an elementary education, and the proportion of graduates is much lower than the national average. The proportion of households with three or more children is higher than the national average and the proportion of unemployed people in households with children is twice as high as the national average. Based on the experience of social workers working in the area, in addition to smoking and drinking alcohol, the consumption of psychoactive and psychotropic substances has increased among adolescents and young adults. Based on various indicators, children regularly consume illegal drugs. The origin and composition of these drugs are typically unknown. According to the reports by drug users, everyday life is easier, and they can escape from problems when under the influence of drugs. Based on the observations of experts, the consumption of various psychoactive substances has harmful effects on behavior, health, learning, and family life. School performance and the ability to think and learn decrease. Drug users are dissatisfied with their lives, have problems with social relationships, engage in partner violence, and may develop antisocial behavior in their lives. [ABSTRACT FROM AUTHOR]

Center-embedded recursion (CER) in natural language is exemplified by sentences such as "The malt that the rat ate lay in the house." Parsing center-embedded structures is in the focus of attention because this could be one of the cognitive capacities that make humans distinct from all other animals. The ability to parse CER is usually tested by means of artificial grammar learning (AGL) tasks, during which participants have to infer the rule from a set of artificial sentences. One of the surprising results of previous AGL experiments is that learning CER is not as easy as had been thought. We hypothesized that because artificial sentences lack semantic content, semantics could help humans learn the syntax of center-embedded sentences. To test this, we composed sentences from 4 vocabularies of different degrees of semantic content due to 3 factors (familiarity, meaning of words, and semantic relationship between words). According to our results, these factors have no effect one by one but they make learning significantly faster when combined. This leads to the assumption that there were different mechanisms at work when CER was parsed in natural and in artificial languages. This finding questions the suitability of AGL tasks with artificial vocabularies for studying the learning and processing of linguistic CER. (Contains 3 tables, 1 figure and 3 footnotes.)

Chronic diseases are a major cause of mortality and morbidity globally, with non-communicable diseases being responsible for most deaths. Older adults are at a higher risk of developing chronic diseases due to various sociodemographic and lifestyle factors such as age, sex, income, education, employment, place of residence, dietary supplementation, tobacco use, and alcohol consumption. Understanding the relationship between these factors and chronic diseases is crucial for identifying vulnerable populations and improving healthcare delivery. Through both an online and an interview-based survey, this cross-sectional study aimed to examine these associations, focusing on adults aged 50 and above, with the goal of identifying potential areas for intervention and prevention. The study found that gender, area of residence, education status, employment status, nutritional supplementation, body mass index (BMI), alcohol usage, and age are associated with the risk of chronic disease, cardiovascular disease, and diabetes. Female gender, higher educational level, employment, normal BMI, and younger age were found to be protective factors, while living in rural areas, alcohol consumption, and older age were identified as risk factors. The study recommends targeted interventions and improved access to healthcare to reduce risk factors and enhance healthcare delivery for better health outcomes. [ABSTRACT FROM AUTHOR]

The Upper Pannonian (UP) sandstone formation has been utilised for thermal water production in Hungary for several decades. Although sustainable utilisation requires the reinjection of cooled geothermal brine into the host rock, only a fraction of the used water is reinjected in the country. UP sandstone formation is reported to exhibit low injectivity, making reinjection challenging, and its petrophysical properties are poorly known, which increases uncertainty in designing operational parameters. The goal of the study is to provide experimental data and to gain a better understanding of formation characteristics that control injectivity and productivity issues in Upper Pannonian sandstone layers. Petrographical characterisation and petrophysical laboratory experiments are conducted on cores retrieved from two wells drilled in the framework of an R&D project at the depth of between 1750 m and 2000 m. The experiments, such as grain density, porosity, permeability, and ultrasonic velocity, as well as thin section, grain size distribution, XRD, and SEM analyses, are used to determine Petrophysical Rock Types (PRT) that share distinct hydraulic (flow zone indicator, FZI) and petrophysical characteristics. These are used to identify well intervals with lower potential for injectivity issues. The results imply that fines migration due to formation erosion is one of the key processes that must be better understood and controlled in order to mitigate injectivity issues at the study area. Future investigation should include numerical and experimental characterisation of formation damage, including water–rock interaction tests, critical flow velocity measurements, and fines migration analysis under reservoir conditions. [ABSTRACT FROM AUTHOR]

The main objective of this study is to calculate the representative elementary volume (REV) according to voxels’ porosity. Physical properties of rock-forming components of a 5 m-long core sample of the Boda Claystone Formation (BCF) were acquired using 3D X-ray computed tomography images. The REV calculation was established using the Autoregressive Integrated Moving Average, Statistical Process Control (ARIMA SPC) technique. This method (ARIMA SPC) was five times iterated by varying positions of starting voxel volume in the core sample: upper left, upper right, lower left, lower right, and middle. The general average range of REV values was from 16.56 cm3 to 46.26 cm3. Monte Carlo simulation with 1,000 runs was used to simulate the long-run properties of REV and the normalized REV of voxel-porosity. The simulated REV values were 64.80 cm3 in the upper left position, 61.44 cm3 for the upper right, 55.59 cm3 for the lower right, 53.77 cm3 for the lower left, and 42.23 cm3 for the middle. According to the simulation of the normalised REVs, their volume percentages were as follows: 40 % for the upper left, 41.34 % in the lower right, 23.86 % for the lower left. Lastly, the upper right and the central (middle) positions had almost the same percentage volumes around 15.5 %. As the initial volume started from any core sample’s corners, the REV porosity range would be between 2.47 % and 2.58 %, which is close to the average voxel porosity of BCF (2.55%). However, a deviant (higher) REV porosity value was attained from the centre initiated volume (~ 2.8 %). Therefore, the middle part of the studied core sample might not be adequate to be considered as an initial voxel volume of the REV calculation. [ABSTRACT FROM AUTHOR]

X-ray computed tomography (CT) can reveal internal, three-dimensional details of objects in a non-destructive way and provide high-resolution, quantitative data in the form of CT numbers. The sensitivity of the CT number to changes in material density means that it may be used to identify lithology changes within cores of sedimentary rocks. The present pilot study confirms the use of Representative Elementary Volume (REV) to quantify inhomogeneity of CT densities of rock constituents of the Boda Claystone Formation. Thirty-two layers, 2 m core length, of this formation were studied. Based on the dominant rock-forming constituent, two rock types could be defined, i.e., clayey siltstone (20 layers) and fine siltstone (12 layers). Eleven of these layers (clayey siltstone and fine siltstone) showed sedimentary features such as, convolute laminations, desiccation cracks, cross-laminations and cracks. The application of the Autoregressive Integrated Moving Averages, Statistical Process Control (ARIMA SPC) method to define Representative Elementary Volume (REV) of CT densities (Hounsfield unit values) affirmed the following results: i) the highest REV values corresponded to the presence of sedimentary structures or high ratios of siltstone constituents (> 60%). ii) the REV average of the clayey siltstone was (5.86 cm3) and (6.54 cm3) of the fine siltstone. iii) normalised REV percentages of the clayey siltstone and fine siltstone, on the scale of the core volume studied were 19.88% and 22.84%; respectively. iv) whenever the corresponding layer did not reveal any sedimentary structure, the normalised REV values would be below 10%. The internal void space in layers with sedimentary features might explain the marked textural heterogeneity and elevated REV values. The drying process of the core sample might also have played a significant role in increasing erroneous pore proportions by volume reducation of clay minerals, particularly within sedimentary structures, where authigenic clay and carbonate cement were presumed to be dominant. [ABSTRACT FROM AUTHOR]

This study aims to analyse the indicators of exclusive breastfeeding and breast-milk-feeding in Hungary for the period 1997--2019. According to the results, among one-year-old children the proportion of infants who were solely breastfed/received only breast milk in their first four months of life constantly declined from 2008 to 2017 (2007: 61.77% vs. 2017: 46.36%). The relevant ratio for infants exclusively breast-/breast-milk-fed in their first six months of life increased significantly between 1997 and 2007 (1997: 23.38% vs. 2007: 42.45%), then decreased with fluctuations (2008: 35.73% vs. 2019: 34.40%). The same indicator for 12-month infants peaked in 2004 (52.37%), but was only 35.63% in 2019. Hungary excels other European countries in terms of indicators defined in the World Health Organization's global nutrition targets for breastfeeding but the favourable national data cover significant disparities between regions (counties). [ABSTRACT FROM AUTHOR]

Continuous Wavelet Transformation (CWT) was applied to study the small-scale repetitive oscillations of porosity distribution patterns in a5m silty-claystone core sample of the Boda Claystone Formation. We handled the fluctuations in voxel porosity averages over unequal depth distributions as signals over uneven time intervals. The strength of wavelet analysis lies in the ability to study the fluctuation of a signal in detail, i.e., the wavelet transforms permit automatic localization of the cyclic attributes' sequences both in time (the depth domain) and according to theirfrequency (the frequency domain). Thereupon, three main frequency branches (cycles) were discerned: small scale (5,6.67, and 11 cm), intermediate scale (20,30 cm), and large scale (66.67 cm). Depending on the CWT coefficients magnitude plot, we were able to detect the developments of porosity oscillation according to the depth variable. Thus, small-scale cycles were seen throughoutthe core sample-, the intermediate-scale cycles were strong in the upper parts of the core sample and dwindled toward greater depths, and the large cycle was predominant in the lower part of the core sample. The cross-correlation of the wavelet coefficients of porosity and rock-forming components allows a detailed study of the inter-dependence of such parameters as their relationship changes over time. The distinct peaks at zero lag indicates that the measured wavelet coefficient series were contemporaneously correlated; their strong positive correlations suggest that both examined series respond similarly and simultaneously to other exogenous factors. The results emphasize that cyclical porosity fluctuations at all scales would concern three main factors, sediment deposition, diagenetic processes, and structural deformation (i.e., convolute laminations). [ABSTRACT FROM AUTHOR]

Abstract: The Boda Claystone Formation (BCF), explored as a possible geological disposal of HLW in Hungary, has peculiar physical and chemical characteristics. Due to the petrophysical behaviour many new methods and experimental development were applied, while the traditional methods, e.g. steady state flow test on the basis of Darcy’s law, are too time-consuming. The pressure pulse decay (PPD) technique destinated to estimating gas and water permeability is one of these new methods developed for the BCF study. The main advantage of the PPD permeability compared with traditional permeability measurements is that very fast (in case of k g ∼10−19 m2 15–25min, k w ∼10−21 m2 6–7h), only 0.1–0.5MPa pressure difference applied in the two sides of the examined core, quasi in situ circumstances can be provided and their uncertainty estimated. For the correct interpretation of results of the three cores originated from different underground boreholes of the formerly URL’s Alpha-1 drift, geochemical, minerological and petrophysical analysis were carried out. The time-consumption of drying, the fact that the dry core absorbed humidity of the atmosphere very fast, as well as the unsuccess of saturation under vacuum drew attention to the importance of the necessity of careful preparation and handling as well as the necessity of geochemical and mineralogical analysis. [Copyright &y& Elsevier]

Surgical complications (SCs) are still high potential causes of graft loss. The incidence has a huge amount of variations depending on many factors. Our aim was to study the postoperative technical complications following kidney transplantations (KTs) during a 5-year period between 2011 and 2015. In the observed time frame there were 47 SCs occurring in 32 (19.4%) patients of 165 KTs. Every complication was classified into 3 groups: vascular (11; 6.6%), urologic (16; 9.7%), and any others (20; 12.1%). The most common postoperative SCs in our center were hemorrhage (14; 8.5%), urinary leakage (12; 7.2%), and renal artery stenosis (6; 3.6%). Twenty-seven patients, 84% of those having had a SC, needed an intervention, mainly a surgical correction (28; 62%). Half of these interventions (21; 51%) were performed due to urologic reasons. As possible predicting factors, we studied the type of arterial and ureter anastomosis in relation to onset of vascular and urologic complications. There was no significant correlation. The same was true for any donor and/or recipient demographic parameters. However, the presence of SCs impaired both patient and graft survival. The cumulative 6-month, 1-, 3-, and 5-year patient survival rates were 97% versus 99%, 93% versus 99%, 84% versus 97%, and 84% versus 97% for patients with/without (w/wo) a SC, respectively ( P = .028). The cumulative 6-month, 1-, 3-, and 5-year graft survival rates were 81% versus 96%, 77% versus 94%, 68% versus 86%, and 54% versus 86% for the same 2 groups, respectively ( P = .003). [ABSTRACT FROM AUTHOR]

Background To ease organ shortage, many transplant centers accept kidneys from expanded-criteria donors (ECDs). Our aim was to analyze the results of ECD grafts in our center. Methods Data on cadaveric donors were retrospectively analyzed between January 2011 and September 2014. Definition of ECD was: (1) donor age ≥60 years, (2) donor age 50 to 59 years, and (3) the presence of 2 among the following criteria: hypertension, serum creatinine >1.5 mg/dL, or death from cerebrovascular accident. Standard-criteria donors (SCDs) were those who did not meet the criteria for an ECD. Results During the observation period, 215 cadaveric donors were reported within our region, and 14 kidneys were offered to our center from Eurotransplant. Ninety-one (40%) among the reported donors were ECDs and 123 (54%) were SCDs. The rates of delayed graft function (DGF) and acute rejection (ARE) were not influenced by transplantation of an ECD graft. The cumulative patient and graft survival rates for ECDs were comparable with those of patients who received an optimal graft. Conclusions ECD grafts can be transplanted safely, without the increased risk of DGF, ARE, and inferior patient and graft survival, in the case of careful patient allocation, and with the use of induction therapy. [ABSTRACT FROM AUTHOR]

Background Organ transplantation has become an organized, routine, widely used method in the treatment of several end-stage diseases. Kidney transplantation means the best life-quality and longest life expectancy for patients with end-stage renal diseases. Transplantation is the only available long-term medical treatment for patients with end-stage liver, heart, and lung diseases. Despite the number of transplantations increasing worldwide, the needs of the waiting lists remain below expectations. Methods One of the few methods to increase the number of transplantations is public education. In cooperation with the University of Debrecen Institute for Surgery Department of Transplantation, the Hungarian National Blood Transfusion Service Organ Coordination Office, and the Local Committee Debrecen of Hungarian Medical Students' International Relations Committee (HuMSIRC), the Gerundium, a new educational program, has been established to serve this target. Gerundium is a special program designed especially for youth education. Peer education means that age-related medical student volunteers educate their peers during interactive unofficial sessions. Results Volunteers were trained during specially designed training. Medical students were honored by HuMSIRC, depending on their activity on the basis of their own regulations. Uniform slides and brochures to share were designed. Every Hungarian secondary school was informed. The Local Committee Budapest of HuMSIRC also joined the program, which helps to expand our activity throughout Hungary. The aim of the program is public education to help disperse disapproval, if presented. Conclusions As a multiple effect, our program promotes medical students to have better skills in the field of transplantation, presentation, and communication skills. Our program is a voluntary program with strong professional support and is free of charge for the community. [ABSTRACT FROM AUTHOR]