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The tropical region is a key area for the interaction between the stratosphere and troposphere. The strong convective activity in the troposphere produces a series of gravity wave activities, which result in strong and widespread turbulence over the region. Therefore, studying the turbulent activity in the western Pacific is essential for understanding the characteristics of atmospheric disturbance over this region, which has the world's most complex circulation system. In this paper, we explore the characteristics of atmospheric turbulence distribution over Guam in this region, and the Thorpe sorting method is used to study one-second resolution radiosonde data from the US. On the basis of the background field and local instability, the turbulence generation mechanism is discussed in detail. Results show that the US high-resolution balloon data are efficacious for tropospheric turbulence retrieval but increasingly affected by instrument noise as altitude increases. It is also found that there is a strong turbulent mixing band caused by both shear instability and static instability near the tropopause, where the turbulence activity is markedly enhanced and characterized by annual oscillation, reaching the maximum from July to September. [ABSTRACT FROM AUTHOR]