1. Comparison of Computed and Acquired DWI in the Assessment of Rectal Cancer: Image Quality and Preoperative Staging.
- Author
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Xia, Yihan, Wang, Lan, Wu, Zhiyuan, Tan, Jingwen, Fu, Meng, Fu, Caixia, Pan, Zilai, Zhu, Lan, Yan, Fuhua, Shen, Hailin, Ma, Qianchen, and Cai, Gang
- Subjects
RECTAL cancer ,CANCER patients ,DIFFUSION magnetic resonance imaging ,SIGNAL-to-noise ratio ,DIAGNOSTIC imaging - Abstract
Objective: The aim of the study was to evaluate the computed diffusion-weighted images (DWI) in image quality and diagnostic performance of rectal cancer by comparing with the acquired DWI. Methods: A total of 103 consecutive patients with primary rectal cancer were enrolled in this study. All patients underwent two DWI sequences, namely, conventional acquisition with b = 0 and 1,000 s/mm
2 (aDWIb1,000 ) and another with b = 0 and 700 s/mm2 on a 3.0T MR scanner (MAGNETOM Prisma; Siemens Healthcare, Germany). The images (b = 0 and 700 s/mm2 ) were used to compute the diffusion images with b value of 1,000 s/mm2 (cDWIb1,000 ). Qualitative and quantitative analysis of both computed and acquired DWI images was performed, namely, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and signal intensity ratio (SIR), and also diagnostic staging performance. Interclass correlation coefficients, weighted κ coefficient, Friedman test, Wilcoxon paired test, and McNemar or Fisher test were used for repeatability and comparison assessment. Results: Compared with the aDWIb1,000 images, the cDWIb1,000 ones exhibited significant higher scores of subjective image quality (all P <0.050). SNR, SIR, and CNR of the cDWIb1,000 images were superior to those of the aDWIb1,000 ones (P <0.001). The overall diagnostic accuracy of computed images was higher than that of the aDWIb1,000 images in T stage (P <0.001), with markedly better sensitivity and specificity in distinguishing T1–2 tumors from the T3–4 ones (P <0.050). Conclusion: cDWIb1,000 images from lower b values might be a useful alternative option and comparable to the acquired DWI, providing better image quality and diagnostic performance in preoperative rectal cancer staging. [ABSTRACT FROM AUTHOR]- Published
- 2022
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