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Many autistic people do not learn they are autistic until adulthood. Parents may wait to tell a child they are autistic until they feel the child is "ready." In this study, a participatory team of autistic and non-autistic researchers examined whether learning one is autistic at a younger age is associated with heightened well-being and Autism-Specific Quality of Life among autistic university students. Autistic students (n = 78) completed an online survey. They shared when and how they learned they were autistic, how they felt about autism when first learning they are autistic and now, and when they would tell autistic children about their autism. Learning one is autistic earlier was associated with heightened quality of life and well-being in adulthood. However, learning one is autistic at an older age was associated with more positive emotions about autism when first learning one is autistic. Participants expressed both positive and negative emotions about autism and highlighted contextual factors to consider when telling a child about autism. Findings suggest that telling a child that they are autistic at a younger age empowers them by providing access to support and a foundation for self-understanding that helps them thrive in adulthood.

Until now, over 30 loci have been identified by linkage analysis of affected families that segregate non-syndromic and dominantly inherited forms of hearing impairment (DFNA). A German family with a nonsyndromic progressive hearing impairment transmitted in autosomal dominant mode was linked to 19q13.3q13.4 by a genome-wide scan. Due to the low Iod-score (1.85 at θ=0.05) for APOC2-locus we extended the fine mapping attempt with further markers in the same chromosomal region. This resulted in significant evidence for linkage to the markers D19S246 and D19S553 (two-point Iod-score of 4.05 and 3.55 at θ=0.0) and a candidate critical region of 14 cM between markers D19S412 and D19S571. This region shows partial overlap with the previously reported DFNA4 critical region. The human gene BAX is orthologous to the rodent Bcl2related apoptosis gene that is temporally expressed during the postnatal period in the developing inner ear of the mouse. BAX, mapping at a distance of no more than 0.73 cM distally to marker D19S553 appeared a likely candidate in our pedigree but genomic sequencing of coding regions and exon/intron boundaries excluded disease-related mutations. However, additional ESTs in the same region remain to be tested. [ABSTRACT FROM AUTHOR]

The retrieval of soil surface parameters, in particular soil moisture and roughness, based on Synthetic Aperture Radar (SAR) data, has been the subject of a large number of studies, of which results are available in the scientific literature. However, although refined methods based on theoretical/analytical scattering models have been proposed and successfully applied in experimental studies, at the operative level very simple, empirical models with a number of adjustable parameters are usually employed. One of the reasons for this situation is that retrieval methods based on analytical scattering models are not easy to implement and to be employed by non-expert users. Related to this, commercially and freely available software tools for the processing of SAR data, although including routines for basic manipulation of polarimetric SAR data (e.g., coherency and covariance matrix calculation, Pauli decomposition, etc.), do not implement easy-to-use methods for surface parameter retrieval. In order to try to fill this gap, in this paper we present a user-friendly computer program for the retrieval of soil surface parameters from Polarimetric Synthetic Aperture Radar (PolSAR) imageries. The program evaluates soil permittivity, soil moisture and soil roughness based on the theoretical predictions of the electromagnetic scattering provided by the Polarimetric Two-Scale Model (PTSM) and the Polarimetric Two-Scale Two-Component Model (PTSTCM). In particular, nine different retrieval methodologies, whose applicability depends on both the used polarimetric data (dual- or full-pol) and the characteristics of the observed scene (e.g., on its topography and on its vegetation cover), as well as their implementation in the Interactive Data Language (IDL) platform, are discussed. One specific example from Germany's Demmin test-site is presented in detail, in order to provide a first guide to the use of the tool. Obtained retrieval results are in agreement with what was expected according to the available literature. [ABSTRACT FROM AUTHOR]