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Purpose: To quantify implant displacement upon axial and oblique force application and comparethe effects of bone quality using an in vitro experimental setup. Materials and Methods: One hundred ninety-two implants were inserted into artificial bone block specimens using a drill guide. Ninety-six implants were placed in soft cancellous bone and loaded in 10-N increments up to 80 N in axial and oblique (30-degree angle) directions (n = 48 in each group). The other 96 implants were inserted in dense artificial bone and loaded in axial and oblique directions in the same force increments. Three-dimensional displacement data were recorded for all implants using a noncontact optical image correlation technique based on photogrammetric principles, and the absolute displacement vector was calculated. Results: There were significant differences in the absolute implant displacement in the different bone densities over all load increments. Implant displacement was significantly higher in soft cancellous bone than in dense bone. Axial and oblique loading revealed significant differences in implant displacement in the cancellous specimens, whereas oblique loading showed increased displacement (339 ± 47 ?m at 80 N) compared to axial loading (266 ± 39 ?m at 80 N). However, axial and oblique loading showed no significant differences over all load increments when implants were inserted in dense specimens (absolute displacement with an 80-N load: 147 ± 10 ?m axial and 126 ± 17 ?m oblique). Conclusions: Bone density influenced implant displacement. The loading character (axial versus oblique) significantly influenced implant displacement in soft cancellous bone block specimens only. However, the limitation of the measured displacement values to an in vitro application that did not represent the complexity of vital bone has to be considered. [ABSTRACT FROM AUTHOR]