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The article discusses the pollution of heavy metals, manifested by the occurrence of such in some edible fishes sampled from four stations in the Gangetic Delta, India. It informs the alarming effects of the metals that exert direct effects on consumers and select-tolerant bacteria inside the body of fishes and the consumers. A study at IGB- Neuglobsow, Germany wherein resistance to antibiotics and heavy metals were detected in various combinations of aquatic isolates is also presented.