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Objective: To search for a link between Chlamydia pneumoniae serological status and venous thromboembolic disease., Methods: From March 1992 to October 1999, we conducted a cross-sectional hospital-based study of consecutive unselected outpatients referred to us for clinical suspicion of venous thromboembolism. We compared the Chlamydia pneumoniae serological status with respectively, the venous thromboembolism, the deep vein thrombosis and the proximal deep vein thrombosis status., Results: Among 1193 patients registered for suspected venous thromboembolism, 1010 samples were available (499 negative and 511 positive patients for venous thromboembolism). Seventy-nine patients were Chlamydia pneumoniae positive. Our work failed to demonstrate any clear association between Chlamydia pneumoniae and venous thromboembolism status. Nevertheless, we identified a statistical difference regarding Chlamydia pneumoniae seropositivity and proximal vein thrombosis status (adjusted odds ratio of 1.70, CI95%: 1.05 to 2.77)., Conclusion: The presence of Chlamydia pneumoniae antibodies might be a minor risk factor for venous thrombosis.

Objective: We report the results of a systematic direct detection screening protocol for Chlamydia trachomatis in urine samples from young women., Material and Method: The study included 1026 patients aged 13 to 30 years. Urine samples were tested with a molecular biology assay: AMP-CT., Results: Thirty-five patients (3.4%) were positive: 80% of the positive patients were aged less than 25 years, 48.6% less than 20 years. All these patients were treated and post treatment controls were negative., Conclusion: This study suggests that national screening programs for Chlamydia trachomatis could be beneficial for women aged between 15 and 25 years and that the "Calmat" law could be modified in consequence.

A multicenter study has been done in France in order to assess the presence of C. trachomatis in the newborn and the young infant. The results show that 4.3% of the infants less than 2 month old are positive. This put forward the question of the screening of pregnant women.