1. Severe and fatal neonatal infections linked to a new variant of echovirus 11, France, July 2022 to April 2023.
- Author
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Grapin M, Mirand A, Pinquier D, Basset A, Bendavid M, Bisseux M, Jeannoël M, Kireche B, Kossorotoff M, L'Honneur AS, Robin L, Ville Y, Renolleau S, Lemee V, Jarreau PH, Desguerre I, Lacaille F, Leruez-Ville M, Guillaume C, Henquell C, Lapillonne A, Schuffenecker I, and Aubart M
- Subjects
- Infant, Newborn, Humans, Male, Female, Enterovirus B, Human genetics, France epidemiology, Echovirus Infections diagnosis, Echovirus Infections epidemiology, Enterovirus Infections diagnosis, Enterovirus Infections epidemiology, Enterovirus, Communicable Diseases
- Abstract
We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3-5 days-old and had severe sepsis and liver failure. This new variant, detected in France since April 2022, is still circulating and has caused more fatal neonatal enterovirus infections in 2022 and 2023 (8/496; 1.6%, seven associated with echovirus 11) compared with 2016 to 2021 (7/1,774; 0.4%). National and international alerts are warranted.
- Published
- 2023
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