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1. Metal/N-Heterocyclic Carbene Complexes: Opportunities for the Development of Anticancer Metallodrugs.

Author

Cisnetti, Federico and Gautier, Arnaud

Subjects
*CARBENES, *CANCER treatment, *MITOCHONDRIA, *CANCER cells
Abstract

Death trap: The rational design of metal/N‐heterocyclic carbene complexes allows mitochondria to be targeted. Activation of several apoptotic processes (which do not include direct DNA damage) induces cell death and significant tumor suppression. [ABSTRACT FROM AUTHOR]

Published
2013
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