1. Diabetes risk score in the diagnostic categories of polycystic ovary syndrome.
- Author
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Moran LJ, Strauss BJ, and Teede HJ
- Subjects
- Adolescent, Adult, Algorithms, Case-Control Studies, Cross-Sectional Studies, Diabetes Mellitus, Type 2 diagnosis, Diabetes Mellitus, Type 2 epidemiology, Female, Finland epidemiology, Humans, Middle Aged, Polycystic Ovary Syndrome complications, Polycystic Ovary Syndrome epidemiology, Research Design, Risk Factors, Young Adult, Diabetes Mellitus, Type 2 etiology, Diagnostic Techniques, Endocrine, Polycystic Ovary Syndrome classification, Polycystic Ovary Syndrome diagnosis
- Abstract
Objective: To assess the Finnish Diabetes Risk Score in polycystic ovary syndrome (PCOS) and in different phenotypes of PCOS and controls., Design: Cross-sectional study., Setting: General community., Patient(s): Overweight premenopausal women with National Institutes of Health (NIH) PCOS (n = 29), non-NIH PCOS (n = 25), or controls (n = 27)., Intervention(s): No intervention provided., Main Outcome Measure(s): Finnish Diabetes Risk Score, anthropometrics, oral glucose tolerance test (OGTT), glucose, insulin, and reproductive hormone levels., Result(s): The women with NIH PCOS had higher adiposity, abdominal adiposity and 120-minute OGTT glucose. The women with NIH and non-NIH PCOS had elevated 120-minute OGTT insulin compared with controls. The women with NIH (11.3 ± 0.7) and non-NIH PCOS (10.4 ± 0.7) had similar diabetes risk scores, but both had higher diabetes risk score compared with controls (7.6 ± 0.8) maintained on adjustment for age and body mass index (BMI). The women with NIH (4%) and non-NIH PCOS (12%) had a lower prevalence of low risk of diabetes scores compared with controls (50%)., Conclusion(s): We report for the first time that women with NIH and non-NIH PCOS have similar Finnish Diabetes Risk Scores and elevated scores relative to controls independent of age and adiposity. Similar clinical screening and treatment practices for type 2 diabetes are warranted for both phenotypes of PCOS., (Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)
- Published
- 2011
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