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1. Clonal expansion of a globally disseminated lineage of Mycobacterium tuberculosis with low IS6110 copy numbers.

Author

Warren RM, Victor TC, Streicher EM, Richardson M, van der Spuy GD, Johnson R, Chihota VN, Locht C, Supply P, and van Helden PD

Subjects
Europe epidemiology, Humans, Minisatellite Repeats, Oligonucleotides analysis, Phylogeny, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, South Africa epidemiology, Tuberculosis microbiology, United States epidemiology, DNA Transposable Elements, Evolution, Molecular, Gene Dosage, Mycobacterium tuberculosis classification, Mycobacterium tuberculosis genetics, Tuberculosis epidemiology
Abstract

Knowledge of the clonal expansion of Mycobacterium tuberculosis and accurate identification of predominant evolutionary lineages in this species remain limited, especially with regard to low-IS6110-copy-number strains. In this study, 170 M. tuberculosis isolates with

Published
2004
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