1. Inflammatory breast cancer: A review from our experience.
- Author
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Mele, Marco, Sørensen, Anne Schmidt, Bruun, Josephine, Funder, Jonas Amstrup, Tramm, Trine, Bodilsen, Anne, Nielsen, Hanne Melgaard, and Christiansen, Peer M.
- Subjects
BREAST cancer ,PROGRESSION-free survival ,LOG-rank test ,THERAPEUTICS ,UNIVERSITY hospitals - Abstract
INTRODUCTION: Inflammatory Breast Cancer (IBC) is a distinct and rare type of breast cancer accounting for up to 6% of all breast cancer cases in Europe. The aim of this study was to investigate diagnostic methods, treatments, and outcome after IBC in patients treated at a single institution in Denmark. METHOD: All patients treated for IBC at Aarhus University Hospital between 2000 and 2014 were identified and included in the cohort. Survival was assessed using Kaplan-Meier curves and log-rank statistics. RESULTS: A total of 89 patients were identified with a median follow up of 3.6 years. The overall survival at 5 and 10 years were 41% and 18%, respectively. The disease free survival at 5 and 10 years were 47% and 27%, respectively. Thirty-four percent had distant metastasis at time of diagnosis. Patients with ER positive tumors had a significantly better overall survival than patients with ER negative tumors (p = 0.01). CONCLUSION: Despite a more aggressive systemic and loco-regional treatment today, IBC is still a very serious disease with a high mortality. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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