1. Regional and physician specialty-associated variations in the medical management of atherosclerotic renal-artery stenosis.
- Author
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Folt DA, Evans KL, Brahmandam S, He W, Brewster PS, Yu S, Murphy TP, Cutlip DE, Dworkin LD, Jamerson K, Henrich W, Kalra PA, Tobe S, Thomson K, Holden A, Rayner BL, Grinfeld L, Haller ST, and Cooper CJ
- Subjects
- Aged, Antihypertensive Agents pharmacology, Atherosclerosis therapy, Canada, Disease Management, Europe, Female, Humans, Internationality, Linear Models, Male, Medicine, Middle Aged, Multivariate Analysis, New Zealand, Practice Patterns, Physicians', Prospective Studies, Renal Artery Obstruction pathology, Risk Assessment, Severity of Illness Index, South Africa, South America, United States, Antihypertensive Agents therapeutic use, Atherosclerosis pathology, Hypertension, Renal diagnosis, Hypertension, Renal drug therapy, Renal Artery Obstruction therapy
- Abstract
For people enrolled in Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL), we sought to examine whether variation exists in the baseline medical therapy of different geographic regions and if any variations in prescribing patterns were associated with physician specialty. Patients were grouped by location within the United States (US) and outside the US (OUS), which includes Canada, South America, Europe, South Africa, New Zealand, and Australia. When comparing US to OUS, participants in the US took fewer anti-hypertensive medications (1.9 ± 1.5 vs. 2.4 ± 1.4; P < .001) and were less likely to be treated with an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker (46% vs. 62%; P < .001), calcium channel antagonist (37% vs. 58%; P < .001), and statin (64% vs. 75%; P < .05). In CORAL, the identification of variations in baseline medical therapy suggests that substantial opportunities exist to improve the medical management of patients with atherosclerotic renal-artery stenosis., (Copyright © 2015 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.)
- Published
- 2015
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