1. Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA.
- Author
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Mendichovszky I, Pullens P, Dekkers I, Nery F, Bane O, Pohlmann A, de Boer A, Ljimani A, Odudu A, Buchanan C, Sharma K, Laustsen C, Harteveld A, Golay X, Pedrosa I, Alsop D, Fain S, Caroli A, Prasad P, Francis S, Sigmund E, Fernández-Seara M, and Sourbron S
- Subjects
- Biomarkers metabolism, Consensus, Delphi Technique, Europe, Expert Testimony, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging instrumentation, Magnetic Resonance Imaging trends, Nephrology trends, Reference Standards, Surveys and Questionnaires, Translational Research, Biomedical trends, United States, Kidney diagnostic imaging, Magnetic Resonance Imaging standards, Nephrology standards, Translational Research, Biomedical standards
- Abstract
Purpose: The potential of renal MRI biomarkers has been increasingly recognised, but clinical translation requires more standardisation. The PARENCHIMA consensus project aims to develop and apply a process for generating technical recommendations on renal MRI., Methods: A task force was formed in July 2018 focused on five methods. A draft process for attaining consensus was distributed publicly for consultation and finalised at an open meeting (Prague, October 2018). Four expert panels completed surveys between October 2018 and March 2019, discussed results and refined the surveys at a face-to-face meeting (Aarhus, March 2019) and completed a second round (May 2019)., Results: A seven-stage process was defined: (1) formation of expert panels; (2) definition of the context of use; (3) literature review; (4) collection and comparison of MRI protocols; (5) consensus generation by an approximate Delphi method; (6) reporting of results in vendor-neutral and vendor-specific terms; (7) ongoing review and updating. Application of the process resulted in 166 consensus statements., Conclusion: The process generated meaningful technical recommendations across very different MRI methods, while allowing for improvement and refinement as open issues are resolved. The results are likely to be widely supported by the renal MRI community and thereby promote more harmonisation.
- Published
- 2020
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