1. Computational methods for exon detection.
- Author
-
Claverie JM
- Subjects
- Animals, Base Sequence, Conserved Sequence, Europe, Humans, Internet, Japan, Molecular Sequence Data, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid, United States, User-Computer Interface, Vertebrates genetics, Computing Methodologies, Databases, Factual, Exons, Genes
- Abstract
Computer methods for the complete and accurate detection of genes in vertebrate genomic sequences are still a long way to perfection. The intermediate task of identifying the coding moiety of genes (coding exons) is now reasonably well achieved using a combination of methods. After reviewing the intrinsic difficulties in interpreting vertebrate genomic sequences, this article presents the state-of-the-art, with an emphasis on similarity search methods and the resources available through Internet.
- Published
- 1998
- Full Text
- View/download PDF