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This article draws on learning from the YOUR World Research project in Ethiopia and Nepal, which uses the socioecological Change-scape framework to understand how participants in research need to be understood within a landscape of changing institutional, environmental, and political contexts. The article explores whether trustful relationships, ownership, and commitment can bring about more effective societal change through research. Through group discussion and reflective perspectives, the authors draw out possible indicators of successful partnership from the different contexts in which YOUR World Research was working. These include histories of interpersonal relationships; shared vision and motivations; building ownership; shared platforms and spaces for dialogue; and flexibility to respond to shocks and changes in context. The article suggests that whilst being realistic about the power and politics of partnership, there are mechanisms in partnership models that can help support high-quality rigorous research whilst creating impact at local, national, and international levels. [ABSTRACT FROM AUTHOR]