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The article focuses the establishment of the South London and Maudsley Hospital, a psychiatric hospital established by psychiatrist Henry Maudsley to treat acute and voluntary patients with out-patient facilities and teaching/research facilities in London, England in 1915. Topics covered include role of cost overruns and the onset of World War I in the delay of the project, reopening of the hospital on January 31, 1923 with Edward Mapother as medical superintendent and status of the hospital.