1. Translation and linguistic validation of the FACT-EGFRI-18 quality of life instrument from English into Dutch.
- Author
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Boers-Doets CB, Gelderblom H, Lacouture ME, Bredle JM, Epstein JB, Schrama NA, Gall H, Ouwerkerk J, Brakenhoff JA, Nortier JW, and Kaptein AA
- Subjects
- Aged, Comprehension, Drug Eruptions diagnosis, Drug Eruptions etiology, Drug-Related Side Effects and Adverse Reactions, England, Epidermal Growth Factor adverse effects, Epidermal Growth Factor therapeutic use, Female, Humans, Linguistics methods, Male, Middle Aged, Netherlands, Risk Assessment, Self Report, Treatment Outcome, Epidermal Growth Factor antagonists & inhibitors, Neoplasms drug therapy, Neoplasms psychology, Quality of Life, Surveys and Questionnaires, Translating
- Abstract
Purpose: The Functional Assessment of Cancer Therapy-Epidermal Growth Factor Receptor Inhibitor 18 (FACT-EGFRI-18) is a patient-reported outcomes questionnaire developed to assess the effect of EGFRI on patients. The FACT-EGFR-18 was translated into Dutch and evaluated in order to document that the translation adequately captures the concepts of the original English-language version of the questionnaire and is readily understood by subjects in the target population., Method: Translation of the FACT-EGFRI-18 from English to Dutch was accomplished by employing the Functional Assessment of Chronic Illness Therapy (FACIT) multilingual translation methodology. Ten native-speaking residents of the target country who reported EGFRI associated dermatological adverse events (dAEs) were asked to review the translation of the harmonized FACT-EGFRI-18., Results: Participants generally found the Dutch FACT-EGFRI-18 easy to understand and complete. In addition, the translation retained the original meaning of the FACT-EGFRI-18 items and instructions. Based on the results of the cognitive debriefing interviews, no changes to improve clarity and comprehension of translations were identified., Conclusions: The Dutch FACT-EGFRI-18 demonstrates content validity and linguistic validity, and was found conceptually equivalent to its English source, thus confirming linguistic validation. The results suggest that the Dutch FACT-EGFRI-18 can be applied to measure dAE related health related quality of life in Dutch-speaking patients undergoing EGFRI therapy. Formal validation of the Dutch FACT-EGFRI-18 is ongoing., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2013
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