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A recent study conducted by researchers from Ain Shams University in Cairo, Egypt, explored the metabolic consequences of polycystic ovary syndrome (PCOS) and their impact on hepatic function in rats fed a high-fat diet. The study aimed to investigate the potential therapeutic role of moderate-intensity exercise in mitigating these PCOS-associated metabolic and hepatic complications. The results showed that moderate-intensity exercise significantly improved insulin resistance and lipid metabolism, reduced liver enzyme activity and inflammatory cytokine levels, and potentially prevented the development of non-alcoholic fatty liver disease (NAFLD) in PCOS rats, regardless of dietary fat content. These findings suggest that exercise may be beneficial in managing the metabolic and hepatic complications associated with PCOS. [Extracted from the article]

A study conducted at Cairo University in Egypt has found that a weekly topical estradiol peel-off mask may be an effective treatment for adult female acne. The study involved twenty female patients who applied the estradiol mask to one side of their face and a placebo mask to the other side for eight weeks. At the end of the treatment period, the side treated with estradiol showed significant improvement in acne lesions compared to the placebo side. The researchers concluded that the estradiol mask could be a convenient, safe, and effective treatment option for adult female acne. However, it is important to note that the study had limitations, including a small number of participants and a limited follow-up period. [Extracted from the article]

Keywords: Mansoura; Egypt; Africa; Cancer; Carcinomas; Drugs and Therapies; Estradiol Congeners; Estradiol Therapy; Estrogens; Genetics; Gonadal Hormones; Health and Medicine; Hormone Replacement Therapy; Liver Cancer; Oncology; Pharmaceuticals; Sex Hormones; Therapeutics; Therapy; Vaginal Agents; Vaginal Preparations EN Mansoura Egypt Africa Cancer Carcinomas Drugs and Therapies Estradiol Congeners Estradiol Therapy Estrogens Genetics Gonadal Hormones Health and Medicine Hormone Replacement Therapy Liver Cancer Oncology Pharmaceuticals Sex Hormones Therapeutics Therapy Vaginal Agents Vaginal Preparations 778 778 1 03/23/23 20230321 NES 230321 2023 MAR 21 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators publish new report on Oncology - Liver Cancer. According to the news reporters, the research concluded: "This study confirmed that lack of NLRP3 inflammasome is involved in HCC progression and 17 beta-estradiol-induced activation of NLRP3 inflammasome may be effective in HCC treatment as it inhibited tumor cell growth and proliferation by triggering CASP1-dependent pyroptosis in HCC cells.". [Extracted from the article]