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Background: Objective assessment of hip dysplasia patients' functional hip joint status routinely involves gait analysis or isokinetic dynamometry. However, these methods have shown equivocal results and have not been employed in the same groups of patients and controls. Purpose: To assess hip flexor and abductor moments by isokinetic dynamometry in the dysplasia patient and controls, for which we previously reported smaller flexor and slightly larger abductor moments during gait in patients compared to controls. Methods: The study was designed as a prospective cohort study (Level of Evidence II) and conducted in a biomechanics laboratory at Aarhus University, Denmark, during 2011. Participants comprised 32 dysplasia patients and 32 age and gender matched controls. Outcome measures were static peak hip flexion moment at 15, 45 and 75° hip flexion; dynamic eccentric and concentric peak hip flexion moment at 60° and 120°/second; dynamic eccentric and concentric hip abductor moment at 30° and 60°/second. Results: Hip dysplasia patients had smaller eccentric peak flexion moments and smaller eccentric and concentric peak abduction moments at all tested velocities. Conclusion: Although dysplasia patients have weaker hip flexion and abductor muscles than controls, their abductor muscles are sufficiently strong to ensure normal function during gait. Hence, gait analysis alone might not reveal the true, subnormal hip joint status in dysplasia patients. We suggest that comprehensive assessment of hip joint function in dysplasia patients should include more strenuous activities than gait, particularly in young(er) patients who are likely to prefer a more active lifestyle. [ABSTRACT FROM AUTHOR]

The aim of the present study was to determine the severity and distribution of assessed muscle weakness and to relate muscle performance to measures of function and quality of life in long-term chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Fourteen patients with 8.7 years (3.3–11.5) of confirmed CIDP consecutively referred to the referral center for CIDP patients at Aarhus University Hospital, Denmark, during the period 1992–2002 were compared with matched healthy controls. The main outcome parameter was muscle performance assessed with isokinetic dynamometry. Overall disability sum score (ODSS), neurological symptom score (NSS), neuropathy impairment score (NIS), health-related quality-of-life survey (SF-36), nerve conduction studies, physical fitness, hand and walking performance, and quantitative sensory testing were secondary variables. The mean (95% CI) isokinetic strength of all measured muscles was reduced by 19.4% (5.9–32.8%) (p < 0.01). In the legs, distal weakness was predominant, strength at ankle being 37.0% (14.7–59.2%) reduced. Isokinetic strength was closely related to manual muscle strength, ODSS, NIS, walking performance, and physical components of SF-36. In conclusion, isokinetic strength relates to measures of function, impairments, gait performance, and physical components of health-related quality of life in long-term CIDP. Furthermore, a detailed characterization of severity and distribution of weakness has been provided using this technique. [ABSTRACT FROM AUTHOR]