1. DNA indicative of human bocaviruses detected in non-human primates in the Democratic Republic of the Congo.
- Author
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Kumakamba C, Ngay Lukusa I, Mbala Kingebeni P, N'Kawa F, Atibu Losoma J, Mulembakani PM, Makuwa M, Muyembe Tamfum JJ, Belais R, Gillis A, Harris S, Rimoin AW, Hoff NA, Fair JN, Monagin C, Ayukekbong J, Rubin EM, Wolfe ND, and Lange CE
- Subjects
- Animals, DNA, Viral blood, Democratic Republic of the Congo, Genome, Viral, Phylogeny, Polymerase Chain Reaction, DNA, Viral isolation & purification, Human bocavirus genetics, Parvoviridae Infections veterinary, Primates virology
- Abstract
Bocaparvoviruses are members of the family Parvovirinae and human bocaviruses have been found to be associated with respiratory and gastrointestinal disease. There are four known human bocaviruses, as well as several distinct ones in great apes. The goal of the presented study was to detect other non-human primate (NHP) bocaviruses in NHP species in the Democratic Republic of the Congo using conventional broad-range PCR. We found bocavirus DNA in blood and tissues samples in 6 out of 620 NHPs, and all isolates showed very high identity (>97 %) with human bocaviruses 2 or 3. These findings suggest cross-species transmission of bocaviruses between humans and NHPs.
- Published
- 2018
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