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3 results on '"Perez I"'

1. Reversed-phase high-performance liquid chromatographic study of thimerosal stability in Cuban recombinant hepatitis B vaccine.

Author

Tleugabulova D and González Perez I

Subjects
Adsorption, Calibration, Chromatography, High Pressure Liquid, Cuba, Drug Stability, Reference Standards, Spectrophotometry, Ultraviolet, Hepatitis B Vaccines analysis, Preservatives, Pharmaceutical analysis, Thimerosal analysis, Vaccines, Synthetic analysis
Abstract

Non-degraded thimerosal was determined in the presence of its decomposition products by directly assaying recombinant hepatitis B vaccine using a reversed-phase liquid chromatographic method. Methanol-water-orthophosphoric acid (65:35:0.9, v/v/v) was used as the eluent. Salicylic acid was employed as an internal standard. The calibration graph was linear (r = 0.99995) up to 2.5 micrograms of thimerosal. Interference from aluminium hydroxide was eliminated by centrifugation. Good stability of thimerosal in the hepatitis B vaccine was demonstrated. The results obtained were in agreement with the recently proposed mechanism of degradation.

Published
1996
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3. [Epidemiology of oral leukoplasia in tobacco industry workers in Havana].

Author

Rosabal López TE, Rodriguez Perez I, Bernal Baláez A, and Santana Garay JC

Subjects
Adult, Aged, Cuba, Female, Humans, Leukoplakia, Oral etiology, Male, Middle Aged, Occupational Diseases epidemiology, Occupational Diseases etiology, Precancerous Conditions epidemiology, Precancerous Conditions etiology, Smoking, Leukoplakia, Oral epidemiology, Plants, Toxic, Nicotiana
Published
1985

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