1. [HIV1 seropositivity and B and D viruses in West Africa].
- Author
-
Soubeyrand J, Niamkey EK, Ouattara SA, Diallo D, Leleu JP, and Beda BY
- Subjects
- Cote d'Ivoire, Female, HIV Seropositivity epidemiology, HIV-1, Hepatitis B epidemiology, Hepatitis D epidemiology, Humans, Male, Prevalence, Prospective Studies, Acquired Immunodeficiency Syndrome complications, HIV Seropositivity complications, Hepatitis B complications, Hepatitis D complications
- Abstract
This study was undertaken to investigate relationships between three widespread viruses in West Africa, i.e. HIV1 and viruses B and D, in Ivory Coast. Serologic tests for viruses B and D were carried out in a random sample of black adults of both sexes with asymptomatic HIV1 seropositivity. Coinfection by virus B or viruses B and D was a common finding. Coinfection with both viruses B and D, but not with virus B alone, was found to be significantly more frequent in these HIV1-infected adults than in a control group with acute viral hepatitis. Potential interactions between the HIV1 and viruses B and D as well as other viruses are discussed. These findings suggest that one or several cofactors acting alone or in combination play a major role in the clinical expression of HIV infection. The results of this study, together with the suggestion put forward by several investigators that B virus infection may increase the severity of AIDS, are evidence in support of the value of immunization against the B virus in the management of AIDS.
- Published
- 1990