1. The Association Between Lipoproteins, Disability, and Physical Function Among Older Costa Rican Adults.
- Author
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Chanti-Ketterl, Marianne, Gamaldo, Alyssa, Andel, Ross, and Thorpe Jr., Roland J.
- Subjects
CHOLESTEROL ,GERIATRIC assessment ,HIGH density lipoproteins ,LONGEVITY ,PULMONARY function tests ,SEX distribution ,TRIGLYCERIDES ,ACTIVITIES of daily living ,BODY movement - Abstract
Objective: To examine the relationship between total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) with disability and physical performance. Method: Wave 1 data were from Costa Rican Longevity and Healthy Aging Study (n = 2,827). Lipoprotein profiles were measured using blood samples. Disability and physical functioning were measured with activities of daily living/instrumental activities of daily living (ADLs/IADLs) and objective assessment of physical performance. Results: Lower HDL-C was associated with greater ADL disability, and lower TC with longer time to pick-a-pencil and Time-Up-Go (TUG) test. Age interacted between (a) TG and lung function, chair stands, and picka- pencil, and (b) HDL-C and TUG. Stratification showed lower TG and longer time picking up a pencil only for those above 84 years. Based on significant interactions with sex, lower TC was associated with slower chair stand time in women and higher HDL-C with slower chair stand time in men. Discussion: Lower levels of lipoproteins may suggest worse physical function, but the association may differ by sex. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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