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Background: pituitary gland tumors are common in geriatric horses and adenomas of the Pars Intermedia are the most frequent. Active adenomas secrete excessive adrenocorticotropic hormone (ACTH) causing equine Cushing’s disease. This neoplasia has not been described in horses in Colombia. Objective: to describe a pituitary adenoma of the Pars Intermedia in a horse. Anamnesis: a 32-year-old neutered male equine of the Silla Argentina breed located in Bogotá‚ Colombia was reported in distress‚ weak condition and pathological decubitus without response to stimulation. The animal was euthanized and sent for veterinary diagnosis. Necropsy findings: severe hirsutism‚ bilateral hyperplasia of the adrenal glands‚ and an enlarged pituitary gland that measured 2.0 × 2.8 × 3.0 cm in size and protruded into the sella turcica. The body of the pituitary gland was flattened when the base of the brain was subjected to tactile pressure. The cut surface of the pituitary gland was yellow and black in color with a nodule of 0.3 × 0.6 × 0.7 cm. Tissue samples from the pituitary and adrenal glands and the skin were collected. Histopathology: an adenoma originated in the Pars Intermedia of the pituitary gland was observed. Skin hormonal dermatosis was also observed. In addition‚ the adrenal glands showed bilateral diffuse hyperplasia of cortical cells arranged in nodules. Immunohistochemistry: ACTH‚ prolactin‚ neural specific enolase (NSE) and glial fibrillary acidic protein (GFAP) were made on pituitary sections. ACTH was prominently detected and appeared as diffuse intracytoplasmic immunostaining in cells of the Pars intermedia. Prolactin‚ NSE and GFAP were negative. Electron microscopy: the adenoma was composed of round or polyhedral cells with intermediate filaments in moderate quantity. There were also reduced number of identifiable secretory granules and moderate accumulation of mitochondria with variable density. The ultrastructure identified adenoma cells with reduced granularity and secretory functions. Conclusion: a pituitary Pars Intermedia adenoma with associated clinical signs is described in a neutered horse. [ABSTRACT FROM AUTHOR]

A 34 months old Colombian creole mare was referred to veterinary clinic of CES University, in Medellin (Colombia), for the surgical extraction of chondroids in both guttural pouch. The patient was intervened by standing surgery using neuroleptanalgesia. The modified Whitehouse technique was subsequently performed on each guttural pouch to extract all the chondroids. Antibiotic and anti-inflammatory treatment, pre and postsurgical, was systemically administered using trimethoprim/sulfadiazine and flunixin meglumine, as well as local sodium penicillin G. After the intervention, the patient was discharged without complications and its respiratory condition came to complete solution. This case report will allow knowing in detail the modified Whitehouse surgical technique along with its surgical challenges and considerations. In Colombia, to date, there are no reports of its use in CCH. [ABSTRACT FROM AUTHOR]

Anamnesis: eight Silla Argentina breed horses imported from Argentina presented with an abnormal gait and skin lesions. Clinical and laboratory findings: all cases showed different degrees of hind limb hyperflexion, atrophy of the lateral digital muscles, skin lesions, and poor body condition. They underwent several clinical and laboratory examinations, including endoscopy of the upper respiratory tract, skin and liver biopsy, blood count, biochemical profile, and electromyography that showed evidence of a neuropathy and dermatitis. Treatment approach: the horses were treated with phenylbutazone and thiamine. The response was patient dependent with different degrees of recovery resulting. Conclusion: this is the first report of an outbreak of bilateral Australian Stringhalt in Colombia and the first associated to skin lesions according to the veterinary medicine scientific literature. [ABSTRACT FROM AUTHOR]

A case of Wooblers syndrome is described in a complete male 14-year-old horse from the town of Cereté (Cordoba, Colombia). This condition is also known as equine cervical vertebral stenotic myelopathy (CVSM), which is a disease characterized by developmental cervical spinal canal stenosis resulting in intermittent or continuous compression of the spinal cord. This patient showed to have signs of incoordination which included stumbling, symmetrical ataxia, paresis or weakness, spasticity and loss of propioception, particularly in the hindquarters, so that radiology was performed to detect cervical spinal canal stenosis at the level of the cervical vertebrae C4. These findings are related as Wooblers syndrome. [ABSTRACT FROM AUTHOR]